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Study reveals contrasting effects of sucralose on insulin and glucose control

Sucralose, a commonly used artificial sweetener, has contrasting effects on insulin secretion and glucose homeostasis. While bolus administration of sucralose enhances insulin secretion and decreases glucose levels, long-term consumption exacerbates insulin resistance and glucose intolerance, particularly in combination with a high-fat diet. The study highlights the involvement of the T1R3-ERK1/2 pathway in sucralose-induced insulin resistance in the liver.

22 Jun 2023

Hypertension drug shown to prevent post-traumatic headaches

A study led by VA Puget Sound Health Care System researchers has shown that prazosin, a drug used to treat high blood pressure, can prevent posttraumatic headaches.

21 Jun 2023

3D-printed vaginal ovules offer promising treatment for endometriosis

3D-printed vaginal ovules offer controlled release and targeted treatment, showing promise for conditions like endometriosis.

20 Jun 2023

Targeting Phage Therapy 2023 showcased the progress and possibilities of phage therapy in future

The 6th World Congress on Targeting Phage Therapy 2023 that was held on June 1-2 in Paris, and gathered more than 150 attendees from 30+ different countries. Targeting Phage Therapy 2023 included more than 71 presentations between major talks, short orals, and posters.

20 Jun 2023

The contribution of transcription factor ROB1 to the pathophysiology of C. albicans-induced candidal infections

Researchers evaluated the function of the zinc finger transcription factor ROB1 and its two phenotypically distinct alleles in the pathogenesis of Candida albicans infections.

20 Jun 2023

Study reveals that wine consumption has an inverse relationship to cardiovascular mortality

Researchers aimed to understand the association between wine consumption and cardiovascular health.

20 Jun 2023

Oral probiotic bacterial strain found to improve dry eye disease in animal model

In a study by a research group at Baylor College of Medicine, oral administration of a commercially available probiotic bacterial strain was found to improve dry eye disease in an animal model.

18 Jun 2023

Injectable osteoporosis drug can be safely administered orally using a novel 'robotic pill'

A proven and effective medication for osteoporosis, which is currently only available as an injection, can be administered orally using a novel "robotic pill," according to a study presented Saturday at ENDO 2023, the Endocrine Society's annual meeting in Chicago, Ill.

18 Jun 2023

Adagrasib shows promise for the treatment of patients with KRAS G12C-mutated non-small cell lung cancer

Researchers from The University of Texas MD Anderson Cancer Center found the KRAS G12C inhibitor adagrasib showed promising activity suppressing cancer growth not only within the lungs but also in brain metastases for patients with KRAS G12C-mutated non-small cell lung cancer.

16 Jun 2023

Trained immunity: its role in COVID-19 and potential in preparing for future infectious outbreaks

Researchers reported on the contribution of trained immune responses to protection against SARS-CoV-2 infections and future pandemics.

16 Jun 2023

$Fruquintinib improved survival in patients with refractory metastatic colorectal cancer$

Fruquintinib improved survival in patients with refractory metastatic colorectal cancer

Researchers from The University of Texas MD Anderson Cancer Center reported study results showing that the targeted therapy fruquintinib significantly improved overall survival (OS) and progression-free survival (PFS) in patients with refractory metastatic colorectal cancer.

16 Jun 2023

New selective targeted therapy for metastatic colorectal cancer prolongs overall survival

A new therapy is on the horizon for patients with metastatic colorectal cancer who have run out of treatment options.

16 Jun 2023

$11.7M from Department of Defense to fund research on discovering a treatment for hydrocephalus

Researchers at the School of Science at IUPUI will lead two grants totaling $11.7 million from the U.S. Department of Defense to fund research on discovering a drug treatment for hydrocephalus, a condition commonly associated with complications from traumatic brain injury that causes cerebrospinal fluid to accumulate in the brain.

15 Jun 2023

Substance P neuropeptides' role in post-COVID-19 conditions suggested in recent study

Scientists review available evidence on the association between post-COVID-19 conditions and tachykinins.

15 Jun 2023

Montana clinics chip away at refugees’ obstacles to dental care

Yu Yu Htwe had never had dental problems, so she was surprised when a dentist told her she had three cavities at her first appointment in this small city in western Montana.

15 Jun 2023

New method of insulin delivery lowers the risk of hypoglycemia compared to current diabetes treatments

Insulin production has, for the last 50 or so years, come with some risks to the patient. Even so, the medication is lifesaving for the estimated 537 million adults living with diabetes worldwide, with that number expected to grow.

15 Jun 2023

Study reveals impressive skin benefits of blueberries

The benefits of topical and dietary blueberry supplementation in preventing environmental stressor-mediated skin damage and preserving skin health.

14 Jun 2023

First population-based food allergy study explores racial and ethnic differences in all age groups

Food allergy has not been on the radar of most racial and ethnic communities. But a new Northwestern Medicine study - the first population-based food allergy study in the U.S. to explore racial and ethnic differences in all age groups - shows why it should be.

14 Jun 2023

Scientists develop two novel oral polio vaccines to bolster WHO's push to eradicate polio

Despite some of the most successful international vaccination campaigns in history, the poliovirus continues to circulate around the world, posing a threat of neurological damage and even paralysis to anyone who is not vaccinated.

14 Jun 2023

From delicacy to danger: The rising tide of shellfish allergies in children revealed

Shellfish consumption is on the rise, but so are shellfish allergies, particularly among children. A recent review delves into the epidemiology, symptoms, diagnosis, and management of shellfish allergies, highlighting the need for improved diagnostic tools and potential allergen immunotherapy.

13 Jun 2023

Oral News and Research

Study reveals contrasting effects of sucralose on insulin and glucose control

Hypertension drug shown to prevent post-traumatic headaches

3D-printed vaginal ovules offer promising treatment for endometriosis

Targeting Phage Therapy 2023 showcased the progress and possibilities of phage therapy in future

The contribution of transcription factor ROB1 to the pathophysiology of C. albicans-induced candidal infections

Study reveals that wine consumption has an inverse relationship to cardiovascular mortality

Oral probiotic bacterial strain found to improve dry eye disease in animal model

Injectable osteoporosis drug can be safely administered orally using a novel 'robotic pill'

Adagrasib shows promise for the treatment of patients with KRAS G12C-mutated non-small cell lung cancer

Trained immunity: its role in COVID-19 and potential in preparing for future infectious outbreaks

Fruquintinib improved survival in patients with refractory metastatic colorectal cancer

New selective targeted therapy for metastatic colorectal cancer prolongs overall survival

$11.7M from Department of Defense to fund research on discovering a treatment for hydrocephalus

Substance P neuropeptides' role in post-COVID-19 conditions suggested in recent study

Montana clinics chip away at refugees’ obstacles to dental care

New method of insulin delivery lowers the risk of hypoglycemia compared to current diabetes treatments

Study reveals impressive skin benefits of blueberries

First population-based food allergy study explores racial and ethnic differences in all age groups

Scientists develop two novel oral polio vaccines to bolster WHO's push to eradicate polio

From delicacy to danger: The rising tide of shellfish allergies in children revealed

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