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Experimental drug ozanimod moderately effective in treatment of ulcerative colitis

Researchers at University of California San Diego School of Medicine have shown that ozanimod (RPC1063), a novel drug molecule, is moderately effective in the treatment of ulcerative colitis. Results of the Phase II clinical trial will appear in the May 5 issue of the New England Journal of Medicine.

5 May 2016

Study emphasizes benefits of newborn screening for CF patients

A new study led by a team from the Research Institute of the McGill University Health Centre and Cystic Fibrosis Canada reinforces the benefits of newborn screening for cystic fibrosis (CF) patients.

5 May 2016

New AVERT system can reduce radiographic dye volume in patients at risk of AKI

In the largest study of its kind, a new device has been found to significantly reduce the volume of radiographic dye without decreasing image quality in patients who are at risk of developing acute kidney injury (AKI) after undergoing a coronary angiography or percutaneous coronary intervention (PCI).

5 May 2016

LifeBridge Health study to explore potential benefits of wireless heart monitoring system

The LifeBridge Health Cardiovascular Institute has launched a pilot study to evaluate the potential benefits of a wireless heart monitoring system for patients with moderate to severe heart failure. The system tracks weight, blood pressure and other measures, and automatically sends the information to doctors and staff at the Cardiovascular Institute. The study is looking at whether this approach, designed to be simple and easy-to-use, can result in better outcomes for patients with heart failure.

5 May 2016

Human milk hormones may play vital role in shaping healthy infant microbiome

A new University of Colorado Anschutz Medical Campus study finds that hormones in breast milk may impact the development of healthy bacteria in infants' guts, potentially protecting them from intestinal inflammation, obesity and other diseases later in life.

5 May 2016

Promising specialty medical home approach to patient-centered, cost-effective care for IBD patients

A specialty medical home--providing expert medical care coordinated with attention to social support and mental health--is a promising new approach to patient-centered, cost-effective care for patients with Crohn's disease and ulcerative colitis, according to a special "Future Directions" paper in the May issue of Inflammatory Bowel Diseases, official journal of the Crohn's & Colitis Foundation of America. The journal is published by Wolters Kluwer.

5 May 2016

High prevalence of depression alongside COPD can impact overall health, treatment effectiveness

Although there have been discussions about chronic obstructive pulmonary disease (COPD), a condition impacting 24 million Americans, and depression, there has been little research showing the impact depression has on patients with COPD. Two studies published in the April issue of the journal CHEST found one in four patients with COPD suffer from depressive symptoms, and if not treated, those symptoms can have a negative effect on their overall health and treatment effectiveness.

4 May 2016

Oral administration of Jakinibs reduces Parkinson's disease pathogenesis in rat model

University of Alabama at Birmingham researchers report the first documentation that suppressing a key cell-signaling pathway in a rat model of Parkinson's disease reduces pathogenesis. Oral administration of AZD1480 — one of the JAK/STAT pathway inhibitors generally known as Jakinibs — lessened the destructive inflammation and nerve cell degradation in the area of the brain affected by Parkinson's.

4 May 2016

LALES study analyzes risk, prevalence of early and late stage AMD among Latinos

The University of Southern California Roski Eye Institute researchers and clinicians published results of the largest population-based study of adult Latinos and age-related macular degeneration (AMD) in the National Eye Institute-funded "Los Angeles Latino Eye Study." The study, published in JAMA Ophthalmology, is the first to analyze the risk and prevalence of early and late stage AMD and its impact on quality of life for older Latinos.

4 May 2016

Study shows syringe-like device acts as traffic cop directing bacteria to carry out infection

A study has found that a syringe-like device used to invade intestinal cells also acts as a traffic cop -- directing bacteria where to go and thereby enabling them to efficiently carry out infection.

4 May 2016

Hepatitis B virus screening for Asian American adults can help prevent onset of liver diseases

A community-based hepatitis B virus screening effort led by UC Davis researchers found that targeted outreach to Asian American populations can identify groups at high risk for infection and direct them to appropriate follow-up care to help prevent the onset of liver diseases, including cancer.

3 May 2016

Yoga, aquatic exercise have positive influence on multiple sclerosis symptoms

Exercise can have a positive influence on certain symptoms of multiple sclerosis: Patients who do yoga and aquatic exercise suffer less from fatigue, depression and paresthesia, as reported by researchers from the University of Basel and the Psychiatric University Clinics Basel in a joint study with colleagues in Iran.

3 May 2016

$Ibrutinib shows added benefit for refractory mantle cell lymphoma patients$

Ibrutinib shows added benefit for refractory mantle cell lymphoma patients

Ibrutinib is a drug for the treatment of rare diseases. It has been approved for the treatment of adults with chronic lymphocytic leukaemia (CLL) or with relapsed or refractory mantle cell lymphoma (MCL) since 2014, and since 2015 also for the treatment of adults with Waldenström macroglobulinaemia. Regarding the treatment of patients with CLL or MCL, the Federal Joint Committee (G-BA) already conducted a benefit assessment and made a decision in 2015.

3 May 2016

Researchers develop SpiroCall that can accurately measure lung function over simple phone call

Most people in the developing world who have asthma, cystic fibrosis or other chronic lung diseases have no way to measure how well their lungs are functioning outside of a clinic or doctor visit.

3 May 2016

Lack of ready financial resources in family affects overall health of children

The connection between a family's income and childhood health has been well-established, with lower income linked to poorer health and a greater likelihood of more chronic conditions. Now a new study by UCLA researchers shows that the size of the paycheck is not all that matters when it comes to children's health risks. So does the amount that a family has tucked away in savings.

30 Apr 2016

Small doses of cancer drug may be potential treatment for sepsis and other pandemics

Results from laboratory experiments and mouse studies suggest that small doses of drugs from a specific class of approved cancer medications called topoisomerase 1 (top1) inhibitors may protect against the overwhelming immune response to infection that sometimes leads to sepsis, a bacterial condition that kills as many as 500,000 people in the United States each year.

30 Apr 2016

Modified surgical technique may be effective treatment option for chronic temporal headache

A modified surgical technique may provide a simpler approach to the surgical treatment for one type of chronic headache, according to an "Ideas and Innovations" paper in the May issue of Plastic and Reconstructive Surgery, the official medical journal of the American Society of Plastic Surgeons (ASPS).

30 Apr 2016

NCCN publishes series of patient education materials for Non-Hodgkin's Lymphoma

It is estimated that more than 72,000 people in the United States will be diagnosed with Non-Hodgkin's Lymphomas (NHL) in 2016. The sixth leading cancer diagnosis in U.S. men and women, NHL has more than 30 sub-types, each featuring unique treatment choices and challenges.

30 Apr 2016

Older women with chronic health problems more likely to have lower quality of life

Researchers writing in the Journal of the American Geriatrics Society recently learned that older women who are frail, and who have six or more chronic health conditions, are twice as likely to have a lower quality of life compared to women with less than three risk factors.

30 Apr 2016

Study sheds light on several aspects of Ebola virus flare-ups in Liberia

Ebola virus samples taken from patients in Liberia in June 2015 are strikingly similar in their genetic makeup to other Ebola virus sequences from Western Africa, according to research published online today in the journal Science Advances. The study sheds light on several aspects of the "flare-ups" that have occurred in Liberia since the country was initially declared free of Ebola virus disease.

30 Apr 2016

Chronic News and Research

Experimental drug ozanimod moderately effective in treatment of ulcerative colitis

Study emphasizes benefits of newborn screening for CF patients

New AVERT system can reduce radiographic dye volume in patients at risk of AKI

LifeBridge Health study to explore potential benefits of wireless heart monitoring system

Human milk hormones may play vital role in shaping healthy infant microbiome

Promising specialty medical home approach to patient-centered, cost-effective care for IBD patients

High prevalence of depression alongside COPD can impact overall health, treatment effectiveness

Oral administration of Jakinibs reduces Parkinson's disease pathogenesis in rat model

LALES study analyzes risk, prevalence of early and late stage AMD among Latinos

Study shows syringe-like device acts as traffic cop directing bacteria to carry out infection

Hepatitis B virus screening for Asian American adults can help prevent onset of liver diseases

Yoga, aquatic exercise have positive influence on multiple sclerosis symptoms

Ibrutinib shows added benefit for refractory mantle cell lymphoma patients

Researchers develop SpiroCall that can accurately measure lung function over simple phone call

Lack of ready financial resources in family affects overall health of children

Small doses of cancer drug may be potential treatment for sepsis and other pandemics

Modified surgical technique may be effective treatment option for chronic temporal headache

NCCN publishes series of patient education materials for Non-Hodgkin's Lymphoma

Older women with chronic health problems more likely to have lower quality of life

Study sheds light on several aspects of Ebola virus flare-ups in Liberia

Managing vibration in IVF laboratories

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

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