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Muscle mass plays key role in cancer survival: Research

In the vast majority of patients with advanced cancer, their muscles will gradually waste away for reasons that have never been well understood. Now, researchers reporting in the August 20 issue of Cell, a Cell Press Publication, have found some new clues and a way to reverse that process in mice. What's more, animals with cancer that received the experimental treatment lived significantly longer, even as their tumors continued to grow.

20 Aug 2010

SIGVARIS joins Vascular Disease Foundation's National Corporate Round Table

The Vascular Disease Foundation (VDF) announced today that SIGVARIS, has become a member of VDF's National Corporate Round Table. The National Corporate Round Table serves to help the foundation in its public awareness and educational efforts.

20 Aug 2010

Research marks new direction to treat Pneumocystis, inflammatory diseases

A drug to treat inflammation plays a surprising role reducing the level of infection caused by an opportunistic bug that is deadly for AIDS and cancer patients and others with weakened immune systems.

20 Aug 2010

Study reports uneven decline of colorectal cancer mortality rate

Black patients die from colorectal cancer at much higher rates than whites do and new research points to unequal health care as the cause. While deaths from colorectal cancer have declined over the past 40 years, the declines have been uneven, said lead author Samir Soneji, Ph.D., of the Robert Wood Johnson Health and Society Scholars Program at the University of Pennsylvania.

20 Aug 2010

Decline in SIDS rate contributes to overall infant mortality reduction in New Jersey

The rate of Sudden Infant Death Syndrome (SIDS), a leading cause of infant mortality, declined in New Jersey by 45 percent between 2000 and 2006, the most recent year for which final SIDS data are available, report Barbara M. Ostfeld, PhD, and Thomas Hegyi, MD, professors in the Department of Pediatrics at UMDNJ-Robert Wood Johnson Medical School and program director and medical director, respectively, for the Sudden Infant Death Syndrome (SIDS) Center of New Jersey.

19 Aug 2010

Assessment of critical illness during Emergency Medical Services care

A prediction score that included such factors as age, blood pressure, heart and respiratory rate for patients who received out-of-hospital emergency care was associated with the development of critical illness during hospitalization such as severe sepsis, the need for mechanical ventilation or death, according to a study in the August 18 issue of JAMA.

19 Aug 2010

Drug-eluting stents improve long-term clinical outcome for patients undergoing angioplasty

Researchers at the Rabin Medical Center in Israel have determined that the use of drug-eluting stents (DES) improves the long-term clinical outcome for patients undergoing percutaneous coronary intervention (PCI), commonly known as angioplasty. Results of this study appear in the September issue of Catheterization and Cardiovascular Interventions, a journal published by Wiley-Blackwell on behalf of The Society for Cardiovascular Angiography and Interventions.

19 Aug 2010

BBC reports on efforts to broaden access to childhood vaccines

The BBC reports on discussions about childhood immunization at the International Pediatric Association (IPA) meeting last week in Johannesburg, South Africa. "Vaccines are a key plank in meeting Millennium Development Goal 4 - to reduce child mortality by two thirds by 2015 - and many sessions at the congress were devoted to them," the news service writes.

18 Aug 2010

Biogen Idec, Knopp Neurosciences enter license agreement for KNS-760704 ALS drug candidate

Biogen Idec and Knopp Neurosciences today announced they have entered into an exclusive, worldwide license agreement under which Biogen Idec will develop and commercialize KNS-760704 (dexpramipexole) for the treatment of amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, and potentially other indications.

18 Aug 2010

Results from TITAN trial of CARILLON Mitral Contour System to be presented at ESC 2010 Congress

Cardiac Dimensions, an early stage company focused on the development of minimally invasive devices for the treatment of mitral valve disease and congestive heart failure, announced today that the 12-month follow-up results from the TITAN trial of the Company's CARILLON Mitral Contour System will be presented at the European Society of Cardiology 2010 Congress on August 29, 2010 in Stockholm.

18 Aug 2010

Health care system delay increases death risk in heart attack patients

For patients with a certain type of heart attack, delay in the time between first contact with emergency medical service to initiation of therapy such as balloon angioplasty is associated with an increased risk of death, according to a study in the August 18 issue of JAMA.

18 Aug 2010

Uniform adoption of national HIV quality performance measures needed

To improve the quality of HIV care and treatment nationwide, 17 measures such as screening and prevention for infections and monitoring of antiretroviral therapy should be adopted uniformly, according to a work group led by a Kaiser Permanente researcher.

18 Aug 2010

Study examines surgical procedures in low-resource settings

A new study shows "that surgery can be safely performed in areas with minimal resources and little or no sophisticated technology," the Los Angeles Times' "Booster Shots" blog reports. The study, published in the Archives of Surgery, examines "almost 20,000 surgical procedures completed in resource-limited areas from 2001 to 2008" by Medecins Sans Frontieres (MSF) (Roan, 8/16).

18 Aug 2010

Study deems gentamicin-collagen sponge ineffective in reducing sternal wound infections

Contradicting previous study results, insertion of a sponge that contains the antibiotic gentamicin at the time of surgical closure following cardiac surgery did not reduce the rate of sternal wound infections after 3 months, compared to patients who did not receive the intervention, according to a study in the August 18 issue of JAMA.

18 Aug 2010

Dysphagia impacts length of hospital stay and prognosis

Researchers from Mount Sinai School of Medicine have found that hospitalized patients with dysphagia, or difficulty swallowing, averaged a 40 percent longer hospital stay than patients without the condition. They also had a generally poorer prognosis. The research is published in the August issue of Archives of Otolaryngology-Head & Neck Surgery, one of the JAMA/Archives journals.

18 Aug 2010

Study examines ways to reduce growing cancer burden in developing world

"The growing burden of cancer in developing countries could be reduced without expensive drugs and equipment, scientists said on Monday, but it requires a global effort similar to the fight against HIV/AIDS," Reuters reports in an article that examines a study published in the Lancet by a group of American scientists who have created the Global Task Force on Expanded Access to Cancer Care and Control in Developing Countries.

17 Aug 2010

Hepatitis C rather than Donor Risk Index is major contributor to poor graft survival in transplant patients

The Donor Risk Index, which assesses donor characteristics impacting liver transplantation outcomes, does not bear the same impact on outcomes on a small scale as is suggested from large-scale, national data.

17 Aug 2010

Bariatric surgery can result in sustained reversal of obesity, type 2 diabetes: Study

Results of a large national study show that nearly three-quarters of obese patients with type 2 diabetes who undergo weight-loss surgery are able to stop insulin and other antidiabetes drugs within six months. In the Johns Hopkins study of insured, obese, diabetic patients, researchers also found that in the third year following surgery, average annual health care costs per patient decreased by more than 70 percent. The study is published in the Archives of Surgery this month.

17 Aug 2010

Use of estrogen alone does not increase lung cancer mortality in postmenopausal women: Study

Use of estrogen alone did not increase lung cancer mortality in postmenopausal women, according to a study published online August 13 in The Journal of the National Cancer Institute. In the Women's Health Initiative (WHI) trial, which consisted of several clinical trials on postmenopausal women, one study showed women with previous hysterectomy taking combined estrogen plus progestin therapy had a statistically significant increase in lung cancer mortality, but not incidence. Other studies with combined hormone therapy have had conflicting results. But the influence of estrogen alone was unclear.

16 Aug 2010

Adverse effects in childhood lead to immune impairment later in life

The emotional pains we suffer in childhood can lead to weakened immune systems later in life, according to a new study.Based on this new research, the amount of this immune impairment even enhances that caused by the stress of caregiving later in life."What happens in childhood really matters when it comes to your immune response in the latter part of your life," explained Janice Kiecolt-Glaser, professor of psychology and psychiatry at Ohio State University. She explained her work at the annual meeting of the American Psychological Association in San Diego.

16 Aug 2010

Mortality News and Research

Muscle mass plays key role in cancer survival: Research

SIGVARIS joins Vascular Disease Foundation's National Corporate Round Table

Research marks new direction to treat Pneumocystis, inflammatory diseases

Study reports uneven decline of colorectal cancer mortality rate

Decline in SIDS rate contributes to overall infant mortality reduction in New Jersey

Assessment of critical illness during Emergency Medical Services care

Drug-eluting stents improve long-term clinical outcome for patients undergoing angioplasty

BBC reports on efforts to broaden access to childhood vaccines

Biogen Idec, Knopp Neurosciences enter license agreement for KNS-760704 ALS drug candidate

Results from TITAN trial of CARILLON Mitral Contour System to be presented at ESC 2010 Congress

Health care system delay increases death risk in heart attack patients

Uniform adoption of national HIV quality performance measures needed

Study examines surgical procedures in low-resource settings

Study deems gentamicin-collagen sponge ineffective in reducing sternal wound infections

Dysphagia impacts length of hospital stay and prognosis

Study examines ways to reduce growing cancer burden in developing world

Hepatitis C rather than Donor Risk Index is major contributor to poor graft survival in transplant patients

Bariatric surgery can result in sustained reversal of obesity, type 2 diabetes: Study

Use of estrogen alone does not increase lung cancer mortality in postmenopausal women: Study

Adverse effects in childhood lead to immune impairment later in life

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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