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Study shows benefits, safety of long-lasting radionuclide therapy for patients with advanced NETs

A first-in-human study presented at the 2018 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging demonstrates the benefits and safety of a new, long-lasting type of radionuclide therapy for patients with advanced, metastatic neuroendocrine tumors.

26 Jun 2018

Study finds byproduct of common prostate cancer drug can stimulate growth of tumor cells

A genetic anomaly in certain men with prostate cancer may impact their response to common drugs used to treat the disease, according to new research at Cleveland Clinic. The findings may provide important information for identifying which patients potentially fare better when treated with an alternate therapy.

26 Jun 2018

Phase 1 clinical trial of poliovirus therapy shows long-term survival benefit for recurrent glioblastoma

A genetically modified poliovirus therapy developed at Duke Cancer Institute shows significantly improved long-term survival for patients with recurrent glioblastoma, with a three-year survival rate of 21 percent in a phase 1 clinical trial.

26 Jun 2018

Are wearable defibrillators a suitable alternative to surgically implanted devices?

Wearable defibrillators may be a safe and effective alternative to surgically implanted devices among children with ventricular arrythmias that increase the risk of sudden cardiac death, according to a new study.

26 Jun 2018

Combating cardiac complications caused by cancer treatment

Amie Goins has completed eight 5K runs in 2018. An impressive feat for a 46-year-old mother with a full-time job and two teenage sons to care for – downright astounding for a woman who was diagnosed with stage 2 breast cancer two days before Christmas last year. She's conquered months of treatment and difficult side effects while continuing to lace up.

26 Jun 2018

Novel theranostic agent designed for precise tumor diagnosis and therapy

A novel, intelligent theranostic agent for precise tumor diagnosis and therapy has been developed that remains as small molecules while circulating in the bloodstream, can then self-assemble into larger nanostructures in the tumor, and be activated by the tumor microenvironment for therapy guided by photoacoustic imaging.

26 Jun 2018

Serotonin enhances speed of learning, study finds

An international team from the Champalimaud Centre for the Unknown, in Portugal, and the University College London, in the UK, has uncovered a previously unknown effect of serotonin on learning.

26 Jun 2018

Unbiased approach reveals how to restore breast cancer drugs’ tumor-killing potential

More than 60 percent of breast cancer cases involve defects in the same biochemical chain of events within cancer cells-- known as the PI3 kinase (PI3K) pathway--but efforts to develop therapies targeting this pathway have met with little success after hundreds of mostly failed clinical trials. And researchers still don't understand why.

26 Jun 2018

New molecular imaging method could help effectively tackle brain conditions

A new molecular imaging method can monitor the success of gene therapy in all areas of the brain, potentially allowing physicians to more effectively tackle brain conditions such as Parkinson's disease, Alzheimer's disease and multiple sclerosis.

26 Jun 2018

UVA research shows true nature of immune cells blamed in Alzheimer's

Immune cells commonly blamed in Alzheimer's and other neurodegenerative diseases are actually precision cleaning machines protecting the central nervous system, new research from the University of Virginia School of Medicine shows.

26 Jun 2018

Study reveals new way to inhibit capillary leakage in sepsis

Leakage from the blood capillaries is a key mechanism leading to septic shock and multiorgan failure, which affect millions of patients annually worldwide. However, there is no effective way to inhibit the vessel leakiness. A new study by scientists at the University of Helsinki and Wihuri Research Institute demonstrates that vascular leakage can be inhibited by targeting vascular integrins.

25 Jun 2018

AbbVie and Calibr collaborate to develop T-cell therapies aimed at cancer

AbbVie , a research-based global biopharmaceutical company, and Calibr, a nonprofit drug discovery division of Scripps Research, today announced a collaboration to develop T-cell therapies aimed primarily at cancer, including solid tumors.

25 Jun 2018

Researchers discover immune profile for effective cancer immunotherapy

In a new study published online June 25, 2018 in Nature Medicine, UC San Francisco researchers have identified a key biological pathway in human cancer patients that appears to prime the immune system for a successful response to immunotherapy drugs known as checkpoint inhibitors.

25 Jun 2018

Researchers work on new treatment that could improve lives of cystic fibrosis patients

Researchers at Oregon State University and Oregon Health & Science University are working on a treatment that holds great promise for improving the lives of cystic fibrosis patients.

25 Jun 2018

Merck announces FDA acceptance of supplemental Biologics License Application for KEYTRUDA

Merck, known as MSD outside the United States and Canada, today announced that the U.S. Food and Drug Administration has accepted for standard review a new supplemental Biologics License Application for KEYTRUDA, Merck's anti-PD-1 therapy, as adjuvant therapy in the treatment of patients with resected, high-risk stage III melanoma and granted a Prescription Drug User Fee Act, or target action, date of February 16, 2019.

25 Jun 2018

AntiCancer's oral drug overcomes gemcitabine resistance in mouse models of human pancreatic cancer

Pancreatic cancer is lethal in about 95% of cases mostly due to failure of first-line therapy gemcitabine. AntiCancer Inc.'s oral methioninase (AC 00619), which is in late pre-clinical development as an anti-cancer as well as an anti-aging drug, has now been shown to overcome gemcitabine resistance in mouse models of human pancreatic cancer, including AntiCancer's patient-derived orthotopic xenograft mouse models.

25 Jun 2018

Study: Men tolerate stress urinary incontinence for years before seeking medical help

Men often tolerate stress urinary incontinence for more than two years before seeking medical help - and one-third put up with it for more than five years, making it important for doctors to check for this problem, a new study from UT Southwestern researchers advises.

25 Jun 2018

Novel model to address post-disaster behavioral health issues may also help other communities

Faculty in LSU Health New Orleans schools of Medicine and Public Health and colleagues report that a collaborative effort to build capacity to address behavioral health and promote community resilience after the 2016 Great Flood in Baton Rouge, LA successfully expanded local behavioral health services delivery capacity and that the model may be useful to other disaster-struck communities.

25 Jun 2018

Fearing deportation, immigrant parents are opting out of health benefits for kids

The fear of family separation is nothing new for many immigrants already living in the U.S. In fact, that fear, heightened in recent weeks, has been forcing a tough decision for a while. Advocates say a growing number of American children are dropping out of Medicaid and other government programs because their parents are not citizens.

25 Jun 2018

ABPI associated with NHS for 70 years in pharmaceutical research

In this special year, both the NHS and the Association of the British Pharmaceutical Industry are celebrating our respective 70th anniversaries. The histories of these two organizations have been inextricably linked since 1948 and our relationship with the NHS continues to go from strength to strength.

25 Jun 2018

Therapy News and Research

Study shows benefits, safety of long-lasting radionuclide therapy for patients with advanced NETs

Study finds byproduct of common prostate cancer drug can stimulate growth of tumor cells

Phase 1 clinical trial of poliovirus therapy shows long-term survival benefit for recurrent glioblastoma

Are wearable defibrillators a suitable alternative to surgically implanted devices?

Combating cardiac complications caused by cancer treatment

Novel theranostic agent designed for precise tumor diagnosis and therapy

Serotonin enhances speed of learning, study finds

Unbiased approach reveals how to restore breast cancer drugs’ tumor-killing potential

New molecular imaging method could help effectively tackle brain conditions

UVA research shows true nature of immune cells blamed in Alzheimer's

Study reveals new way to inhibit capillary leakage in sepsis

AbbVie and Calibr collaborate to develop T-cell therapies aimed at cancer

Researchers discover immune profile for effective cancer immunotherapy

Researchers work on new treatment that could improve lives of cystic fibrosis patients

Merck announces FDA acceptance of supplemental Biologics License Application for KEYTRUDA

AntiCancer's oral drug overcomes gemcitabine resistance in mouse models of human pancreatic cancer

Study: Men tolerate stress urinary incontinence for years before seeking medical help

Novel model to address post-disaster behavioral health issues may also help other communities

Fearing deportation, immigrant parents are opting out of health benefits for kids

ABPI associated with NHS for 70 years in pharmaceutical research

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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