G Protein News and Research

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Help for children with rheumatic heart disease

These bacteria carry a special protein sequence, the so-called PARF motif, on their surface.

2 Mar 2009

Blocking one protein RANK function inhibits bone loss

Soo Young Lee and colleagues, at Ewha Womans University, Republic of Korea, have developed a cell-permeable inhibitor of the mouse protein RANK (which they termed RRI) that is likely to aid in the development of selective drugs to treat diseases that involve substantial bone loss, for example, osteoporosis, periodontitis, and arthritis.

2 Mar 2009

Discovery of gene involved in pancreatic cancer

Researchers from the University of Michigan Comprehensive Cancer Center have identified a gene that is overexpressed in 90 percent of pancreatic cancers, the most deadly type of cancer.

2 Mar 2009

Deciphering motor neuron disease

Dr Ian Blair and Professor Garth Nicholson from the University of Sydney's ANZAC Research Institute have identified a new gene abnormality that causes the fatal paralysis, motor neuron disease (MND) in families with multiple members affected by the disease.

1 Mar 2009

Researchers isolate gene mutations in patients with inherited amyotrophic lateral sclerosis

Researchers at the University of Massachusetts Medical School (UMMS) have discovered a new gene whose mutations cause familial amyotrophic lateral sclerosis (ALS), a fatal neurological disorder.

26 Feb 2009

New gene associated with Lou Gehrig's disease

A collaborative research effort spanning nearly a decade between researchers at Massachusetts General Hospital (MGH) and King's College London (KCL) has identified a novel gene for inherited amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig's disease).

26 Feb 2009

Antibody recognition of a highly conserved epitope across influenza viruses

The discovery of the molecule, an antibody known as CR6261, is good news for researchers who hope to design a flu vaccine that would give humans lifelong protection against a majority of influenza viruses.

26 Feb 2009

Scientists develop general-purpose method for detecting trace chemicals

Described in an advance, online publication of the journal Nature Biotechnology on February 22, 2009, the team's general method could be adapted for detecting a wide variety of compounds, including many that are relevant to diagnostic medicine and environmental work.

26 Feb 2009

Why do teeth form in a single row?

A system of opposing genetic forces determines why mammals develop a single row of teeth, while sharks sport several, according to a study published in the journal Science.

26 Feb 2009

Proepithelin encourages cell growth and migration in prostate cancer

Researchers from Thomas Jefferson University have identified a protein that appears to play a significant role in the growth and migration of prostate cancer cells, especially androgen-independent prostate cancer cells.

26 Feb 2009

How obesity, diet and exercise influence our metabolism and interact with our genome

Research by kinesiology investigator Dustin Hittel, PhD, has proven that muscle in extremely obese individuals produces large amounts of a protein called myostatin, which normally inhibits muscle growth-suggesting that for Type 2 diabetics, and the very obese, the task of getting healthy may be more difficult than initially thought.

26 Feb 2009

Heart-healthy diets that reduce calorie intake promote long-term weight loss

Heart-healthy diets that reduce calorie intake - regardless of differing proportions of fat, protein, or carbohydrate - can help overweight and obese adults achieve and maintain weight loss, according to a study funded by the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health, and published Feb. 26, 2009, in the New England Journal of Medicine.

26 Feb 2009

Research points to new antiviral drugs and universal influenza vaccines

WHAT: Researchers at The Scripps Research Institute in La Jolla, California, supported in part by the National Institutes of Health, have identified a common Achilles' heel in a wide range of seasonal and pandemic influenza A viruses.

26 Feb 2009

Blood clots after hip and knee replacements

As the number of hip and knee replacements skyrocket into the coming years, patients and orthopaedic surgeons need to work together to evaluate and assess a potentially fatal complication - blood clots.

26 Feb 2009

A second MND gene mutation in one year signifies rapid research progress

A collaborative research project involving Professor Christopher Shaw of the Institute of Psychiatry, King's College London (KCL), Dr Tom Kwiatkowski at Massachusetts General Hospital (MGH) and Professor Robert H Brown at University of Massachusetts, has revealed that mutations in a gene called FUS (fused in sarcoma) cause familial Motor Neuron Disease (also known as Amyotrophic Lateral Sclerosis).

26 Feb 2009

Discovery of gene that modifies severity of cystic fibrosis lung disease

Researchers have discovered a gene that modifies the severity of lung disease in people with the lethal genetic condition, cystic fibrosis, pointing to possible new targets for treatment, according to a new study in Nature.

25 Feb 2009

Discovery of gene that modifies severity of cystic fibrosis lung disease

25 Feb 2009

Comparison of popular diets

Many popular diets emphasize either carbohydrate, protein or fat as the best way to lose weight.

25 Feb 2009

Protein found linking stress and depression

Stress, the ever-present threat to health and happy living, is tough on the brain. If the strain goes on too long, it can lead to debilitating psychological problems.

25 Feb 2009

Brain protein may be a target for fast-acting antidepressants

It takes weeks or months for the effect of most antidepressants to kick in, time that can feel like an eternity to those who need the drugs the most. But new research suggests that a protein called p11, previously shown to play a role in a person's susceptibility to depression, activates a serotonin receptor in the brain known for producing

25 Feb 2009