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Testing hundreds of existing therapeutics to fight blood cancer more effectively

Multiple myeloma is a rare blood cancer caused by the uncontrolled multiplication of abnormal plasma cells.

27 Apr 2023

Research develops unique delivery system to treat osteosarcoma

New research has identified a potential therapeutic target and developed a unique delivery system to treat osteosarcoma, a bone cancer that primarily affects children and adolescents.

27 Apr 2023

Does oral exposure to cannabidiol (CBD) have toxic implications?

Researchers reviewed the implications of oral exposure to cannabidiol (CBD).

25 Apr 2023

New computational method identifies routes of cellular differentiation in acute myeloid leukemia

Researchers have developed a new method to distinguish between cancerous and healthy stem cells and progenitor cells from samples of patients with acute myeloid leukemia (AML), a disease driven by malignant blood stem cells that have historically been difficult to identify.

24 Apr 2023

Research findings could help inform more effective therapies for AML

Acute myeloid leukemia (AML) is a type of cancer in which the bone marrow makes a large number of abnormal blood cells. It is the most common type of acute leukemia in adults.

24 Apr 2023

Mitophagy helps blood cancer cells to evade the killing effects of BH3 mimetic drug

Despite the promise of new medications that promote cancer cell death in people with acute myeloid leukemia, leukemic cells often adopt features that let them evade the drugs' effects within a year.

24 Apr 2023

Trial recommends replacing skull section following surgery to treat brain hemorrhage

A major international trial has concluded that, where possible, surgeons should replace the removed section of the skull following surgery to treat a form of brain hemorrhage.

24 Apr 2023

Bioengineered drug candidate can counter S. aureus infection in early tests

Researchers at NYU Grossman School of Medicine and Janssen Biotech, Inc. have shown in early tests that a bioengineered drug candidate can counter infection with Staphylococcus aureus – a bacterial species widely resistant to antibiotics and a major cause of death in hospitalized patients.

24 Apr 2023

Pain, hope, and science collide as athletes turn to magic mushrooms

The boxer felt broken. Every day, he was waking up in pain. Some days, it was debilitating headaches. Other times, it was his back. Or his fists. His ribs. His nose. On top of that, he had mood swings. Depression. Anxiety.

24 Apr 2023

Researchers develop a backpack-based myeloid cell therapy for MS patients

Multiple sclerosis (MS) is a devastating autoimmune disease that destroys the protective myelin covering around nerves, disrupting communication between the brain and body, and causing patients' ability to move and function to progressively decline.

21 Apr 2023

New injectable cell therapy shows promise for treating osteoarthritis

Wake Forest Institute for Regenerative Medicine (WFIRM) scientists have created a promising injectable cell therapy to treat osteoarthritis that both reduces inflammation and also regenerates articular cartilage.

21 Apr 2023

What bone and cardiovascular consequences are associated with aluminum intoxication and accumulation?

Researchers aimed to detect the diagnosis of bone aluminum (Al) accumulation and its consequences on bone and heart health.

21 Apr 2023

Novel approach promotes bone regeneration in mice without implantation

Young babies and newborn mice can naturally heal damage to the bones that form the top of the skull, but this ability is lost in adults.

20 Apr 2023

Preclinical study reveals a potential new therapeutic approach to treating common lung cancer

Researchers at the Icahn School of Medicine at Mount Sinai have demonstrated in a preclinical study a potential new therapeutic approach to treating the most common form of lung cancer.

20 Apr 2023

New discovery may lead to improved treatments for women with osteoporosis

Van Andel Institute scientists have pinpointed a key driver of low bone density, a discovery that may lead to improved treatments with fewer side effects for women with osteoporosis.

20 Apr 2023

Sleeve gastrectomy can cause loss of bone density and strength in adolescents

Sleeve gastrectomy (SG), where about 80% of the stomach is removed, is effective for treating obesity and its complications, but it has been associated with bone loss in adolescents.

20 Apr 2023

Nonsurgical system for controlled delivery of antibiotics to treat aggressive periodontitis in adolescents

Aggressive periodontitis is a severe type of gum infection that causes the destruction of ligament and bone and can lead to tooth loss in otherwise healthy individuals.

20 Apr 2023

Newly discovered protein may be pivotal for traumatic heterotopic ossification

A team led by UT Southwestern Medical Center researchers has discovered a protein that appears to be pivotal for traumatic heterotopic ossification (HO), a condition in which bone forms in muscles, tendons, and other soft tissues after traumatic injury or surgery.

19 Apr 2023

Precise genome editing approach can correct mutation that causes sickle cell disease

Scientists at St. Jude Children’s Research Hospital and the Broad Institute of MIT and Harvard showed how prime editing can correct the mutation that causes sickle cell disease in a potentially curative approach.

18 Apr 2023

Children with ALL living in extreme poverty face two-fold greater risk of relapse

Children with acute lymphoblastic leukemia (ALL) who live in extreme poverty and were undergoing maintenance therapy faced an almost two-fold greater risk of relapse compared with kids who weren't as poor, according to a study published in today's issue of Blood.

18 Apr 2023

Bone News and Research

Testing hundreds of existing therapeutics to fight blood cancer more effectively

Research develops unique delivery system to treat osteosarcoma

Does oral exposure to cannabidiol (CBD) have toxic implications?

New computational method identifies routes of cellular differentiation in acute myeloid leukemia

Research findings could help inform more effective therapies for AML

Mitophagy helps blood cancer cells to evade the killing effects of BH3 mimetic drug

Trial recommends replacing skull section following surgery to treat brain hemorrhage

Bioengineered drug candidate can counter S. aureus infection in early tests

Pain, hope, and science collide as athletes turn to magic mushrooms

Researchers develop a backpack-based myeloid cell therapy for MS patients

New injectable cell therapy shows promise for treating osteoarthritis

What bone and cardiovascular consequences are associated with aluminum intoxication and accumulation?

Novel approach promotes bone regeneration in mice without implantation

Preclinical study reveals a potential new therapeutic approach to treating common lung cancer

New discovery may lead to improved treatments for women with osteoporosis

Sleeve gastrectomy can cause loss of bone density and strength in adolescents

Nonsurgical system for controlled delivery of antibiotics to treat aggressive periodontitis in adolescents

Newly discovered protein may be pivotal for traumatic heterotopic ossification

Precise genome editing approach can correct mutation that causes sickle cell disease

Children with ALL living in extreme poverty face two-fold greater risk of relapse

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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