High Throughput News and Research

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Researchers identify genetic abnormalities that lead to skin SCC

Squamous cell carcinoma (SCC) of the skin is one of the most frequent cancers in humans affecting more than half million new persons every year in the world. The transformation of a normal cell to a cancer cell is caused by an accumulation of genetic abnormalities in the progeny of single cells. The spectrum of genetic anomalies found in a variety of human cancers have been described.

14 Jul 2015

UMass Amherst scientist to study how estrogen-mimicking chemicals in the womb can increase breast cancer risk

Much attention has been paid to genetics in breast cancer as disease rates rise, but most women have no family history of the disease, suggesting that there is an environmental risk we don't yet understand, says environmental health scientist Laura Vandenberg in the School of Public Health and Health Sciences at the University of Massachusetts Amherst.

13 Jul 2015

UC San Diego, GSK collaborate to treat leukemia by eliminating cancer stem cells

Researchers at the University of California, San Diego School of Medicine and Moores Cancer Center are working with GSK on a bench-to-bedside project to treat leukemia and other diseases by eliminating cancer stem cells. The collaboration is part of GSK's Discovery Partnerships with Academia (DPAc) program, where academic partners become core members of drug-hunting teams.

9 Jul 2015

Chromosomal abnormalities in embryos created for IVF can be predicted at earliest stage of human development

Scientists at Oregon Health & Science University, Stanford University, University of Valencia and IGENOMIX have discovered that chromosomal abnormalities in human embryos created for in vitro fertilization, or IVF, can be predicted within the first 30 hours of development at the cell-1 stage which results from the union of a female egg and male sperm.

8 Jul 2015

EPFL scientists identify lansoprazole as potential candidate against tuberculosis

Testing thousands of approved drugs, EPFL scientists have identified an unlikely anti-tuberculosis drug: the over-the-counter antacid lansoprazole (Prevacid).

7 Jul 2015

BGI's DNA sequencing laboratory in Hong Kong accredited by CAP

BGI announced today that its high-throughput DNA sequencing laboratory in Hong Kong has been accredited by the American College of Pathologists. The BGI Hong Kong facility is the first clinical next-generation-sequencing laboratory to receive the CAP certification in China, meeting the highest standard in clinical laboratory practices.

2 Jul 2015

Nuclea and Aelan partner to develop, commercialize novel biomarker tests using STEM cells as models

Nuclea Biotechnologies Inc. announced today that it is partnering with Aelan Cell Technologies Inc. (San Francisco, California) for the development, validation and commercialization of novel biomarker tests and companion diagnostics using human STEM cells as models.

1 Jul 2015

Scientists develop high-throughput strategy to build de novo genomes

Scientists from the Icahn School of Medicine at Mount Sinai have developed a new approach to build nearly complete genomes by combining high-throughput DNA sequencing with genome mapping. The methodology enabled researchers to detect complex forms of genomic variation, critically important for their association with human disease, but previously difficult to detect.

30 Jun 2015

Sanford-Burnham gets $100 million gift from Conrad Prebys

Sanford-Burnham Medical Research Institute (Sanford-Burnham) announced today that it has received a gift of $100 million from prominent San Diego developer, philanthropist, and Sanford-Burnham honorary trustee Conrad Prebys.

24 Jun 2015

Broad Institute teams up with Google to increase access to research tools

Broad Institute of MIT and Harvard is teaming up with Google Genomics to explore how to break down major technical barriers that increasingly hinder biomedical research by addressing the need for computing infrastructure to store and process enormous datasets, and by creating tools to analyze such data and unravel long-standing mysteries about human health.

24 Jun 2015

Hiroshima University researchers study promising biomarker for severity of ARWMCs, endothelial function

A promising biomarker for the severity of age-related white matter changes (ARWMCs) and endothelial function was evaluated at Hiroshima University, Japan. The relationship between this biomarker, the telomeric 3'-overhang (G-tail) length, and cardiovascular risk in humans is unclear so far.

23 Jun 2015

Roche unveils series of new diagnostic technologies at EuroMedLab

Today at the 21st annual meeting of the IFCC-EFLM European Congress of Clinical Chemistry and Laboratory Medicines in Paris, France, Roche unveiled a series of new diagnostic technologies.

23 Jun 2015

TSRI scientists devise powerful set of chemical methods to explore protein biology

Scientists at The Scripps Research Institute (TSRI) have devised a powerful set of chemical methods for exploring the biology of proteins.

22 Jun 2015

Canadian and Israeli researchers meet to discuss underlying mechanisms that drive pancreatic cancer

Leading Canadian and Israeli scientists gathered at the Hebrew University of Jerusalem's Faculty of Medicine to attend a forum on pancreatic cancer research and help dedicate the Alex U. Soyka Pancreatic Cancer Research Project.

18 Jun 2015

Optimised ChIP protocols for qPCR and sequencing

Chromatrap®, a business unit of Porvair Sciences, has announced a new web page that brings together protocols developed using their proprietary solid state chromatin immunoprecipitation (ChIP) technology.

From Chromatrap® - Porvair Sciences Ltd 17 Jun 2015

CQDM, OCE grant $1.5M to speed up drug discovery and development in Quebec-Ontario Life Sciences Corridor

CQDM and Ontario Centres of Excellence will fund five highly innovative and unconventional game-changing research and development projects to accelerate drug discovery in the Quebec-Ontario Life Sciences Corridor. Partners are granting $1.5M to Quebec-based and, for the first time, Ontario-based researchers thanks to the partnership with OCE through CQDM's 2014 Explore Program, one of CQDM's flagship programs focusing on early concept validation of cutting-edge technologies that address the most crucial needs in drug discovery and development.

17 Jun 2015

High throughput media preparation at the Institut Curie

The Institut Curie (Paris, France), a world leader in oncology research, has reported how it has standardised on using MEDIACLAVE media preparation and MEDIAJET automated petri dish filling systems from INTEGRA Biosciences to prepare its petri dishes.

From INTEGRA Biosciences 14 Jun 2015

Sebia’s Capillarys 3 Tera automated electrophoresis solution receives CE mark

Sebia, the world leader in capillary electrophoresis, today announces that Capillarys 3 Tera now has the CE mark for HbA1c and serum protein testing, and immunotyping. The CE mark for these tests is the first step in bringing the Capillarys 3 suite to market.

12 Jun 2015

Southern Indiana to be oasis free from Lyme disease, finds Indiana University researcher

Over nearly 15 years spent studying ticks, Indiana University's Keith Clay has found southern Indiana to be an oasis free from Lyme disease, the condition most associated with these arachnids that are the second most common parasitic disease vector on Earth.

11 May 2015

T cell expansion technology: an interview with Alexander Malykhin, CVPF, University of Pennsylvania

T cells are taken from the patient’s blood and then modified using lentivirus, adenovirus or RNA electroporation.

From Beckman Coulter Life Sciences - Flow Cytometry 5 May 2015