Immunodeficiency News and Research

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Immunodeficiency (or immune deficiency) is a state in which the immune system's ability to fight infectious disease is compromised or entirely absent.

Australian scientists rejuvenate the immune systems of mice and humans using a common hormone

The scientists, led by Associate Professor Richard Boyd and Dr Jayne Sutherland from the Monash Immunology and Stem Cell Laboratories, have revitalised the thymus which produces the T cells required to fight infection but which shuts down from early adulthood.

11 Aug 2005

Majority of Americans believe that vaccines are the best hope for controlling the global AIDS epidemic

But while most of those surveyed felt it personally important to help support HIV vaccine research, a majority expressed reluctance to support a friend or family member's participation in an HIV vaccine clinical trial.

9 Aug 2005

Discovery may lead to new diagnostic tests for immunoglobulin A (IgA) deficiency and common variable immunodeficiency (CVID)

Defects in a single gene can result in two immune system disorders that leave affected individuals vulnerable to frequent or unusually severe infections, according to new findings reported in the August issue of Nature Genetics.

4 Aug 2005

New findings could help scientists design more effective treatments to slow or halt the progression of HIV infection

Random fluctuations in gene expression can influence the fates of cells infected with human immunodeficiency virus (HIV) far more than previously thought, according to new research from Howard Hughes Medical Institute (HHMI) researchers at the University of California, Berkeley.

28 Jul 2005

Molecular link between a viral infection and development of a common and fatal form of liver cancer

Researchers at The University of Texas M. D. Anderson Cancer Center have uncovered a crucial molecular link between a viral infection and development of a common and fatal form of liver cancer. In the process, they have identified a possible way to treat this disease as well as a number of other cancers.

26 Jul 2005

Discovery of a receptor that appears to function as one "lock" that HSV opens to allow it to enter human cells

It's one of the most common viruses in America, and one that causes the most guilt and shame. It can get inside almost any kind of human cell, reproduce in vast numbers, and linger for years in the body, causing everything from recurrent genital blisters to sores around the mouth. Its complications can kill, and it may increase susceptibility to many nerve and brain disorders.

24 Jul 2005

Crucial molecular link between a hepatitis B virus (HBV) and hepatocellular carcinoma (HCC)

21 Jul 2005

New design for HIV vaccine trials in animals

Emory University researchers have proposed a new design for HIV vaccine trials in animals that would more closely mimic how humans are exposed to the virus - potentially giving AIDS researchers a more effective tool in developing successful treatments to prevent HIV infection.

20 Jul 2005

Scientists have identified the first reported case in Asia of primate-to-human transmission of simian foamy virus

...a retrovirus found in macaques and other primates that so far has not been shown to cause disease in humans.

13 Jul 2005

Sirna Therapeutics granted new UK patents

Sirna Therapeutics has announced that the United Kingdom (UK) Patent Office has granted the Company two additional short interfering RNA (siRNA) target patents. The first patent covers any siRNA with one or more chemical modifications targeting Vascular Endothelial Growth Factor (VEGF).

12 Jul 2005

Newly discovered gene mutation may account for many cases of immune deficiency

...in particular two syndromes known as immunoglobulin A (IgA) deficiency and Common Variable Immunodeficiency (CVID), report researchers in the July issue of Nature Genetics. The discovery may lead to a new diagnostic test for these conditions, which make people highly susceptible to infections and often go unrecognized because of a lack of good tests.

11 Jul 2005

New discoveries in treatment for patients with non-Hodgkin's lymphoma

Three scientific studies - each highlighting new discoveries in treatment for patients with non-Hodgkin's lymphoma - were announced at the Society of Nuclear Medicine's 52nd Annual Meeting June 18–22 in Toronto.

20 Jun 2005

Prototype drug shows promise in slowing replication of the virus responsible for SARS

A prototype drug created by researchers at the University of Illinois at Chicago shows promise in slowing replication of the virus responsible for severe acute respiratory syndrome, or SARS.

8 Jun 2005

Risk factors for tuberculosis in the United States overlap with many of the risk factors associated with persistent homelessness

...including being male or having a history of incarceration or substance abuse, according to a report in the June 8 issue of JAMA, a theme issue on tuberculosis.

8 Jun 2005

Gene therapy for arthritis is both feasible and safe

Gene therapy for arthritis and other non-terminal, debilitating conditions and diseases is both feasible and safe, report researchers who conducted the world's first such test on the approach in patients with advanced rheumatoid arthritis.

6 Jun 2005

Research provides roadmap for the development of human therapies for cytomegalovirus (CMV)

McGill University Health Centre (MUHC) researchers have defined genetic resistance to the widespread virus, cytomegalovirus (CMV)--a member of the viral group that causes some of the world's most prevalent diseases, such as herpes, chicken pox and mononucleosis.

26 May 2005

Antiretroviral therapy may prevent excess risk of some cancers in people with HIV

In people infected with human immunodeficiency virus (HIV), highly active anti-retroviral therapy (HAART) may prevent most excess cases of Kaposi sarcoma and non-Hodgkin lymphoma, according to a new study in the March 16 issue of the Journal of the National Cancer Institute.

18 May 2005

Antibiotic minocycline might help alleviate HIV's negative effects on the brain and central nervous system

By studying animals, Johns Hopkins researchers have discovered that the antibiotic minocycline might help alleviate HIV's negative effects on the brain and central nervous system, problems that can develop even though antiretroviral therapy controls the virus elsewhere in the body.

1 May 2005

HIV epidemic among young men unabated because many are unaware they are infected

U.S. health officials say many young gay and bisexual men who are HIV-positive are unaware they have the virus.

26 Apr 2005

As syphilis rates increase in Los Angeles County, new study suggests the disease is increasing HIV rates

The syphilis epidemic among men who have sex with men in Los Angeles County may be contributing to rates of HIV in this population, according to a new report published in the Journal of Acquired Immune Deficiency Syndrome.

23 Apr 2005