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Insight into hereditary diseases

Hereditary diseases such as epilepsy or various coordination disorders may be caused by changes in nerve cells of the cerebellum, which do not set in until after birth. This is reported by Bochum's neuroscientists in the Journal of Neuroscience.

19 Mar 2011

Study reveals new mechanism underlying reproduction in plants

A team of researchers at the Instituto Gulbenkian de Ci-ncia (IGC), Portugal, discovered that pollen, the organ that contains the plant male gametes, communicate with the pistil, their female counterpart, using a mechanism commonly observed in the nervous system of animals.

18 Mar 2011

pIMAGO nanopolymer can test cancer drug efficacy against biochemical processes

A Purdue University scientist's nanopolymer would make it easier and cheaper for drug developers to test the effectiveness of a widely used class of cancer inhibitors.

17 Mar 2011

Pig model reveals how cystic fibrosis gene mutation causes disease

It's been more than 20 years since scientists first discovered the gene that causes cystic fibrosis (CF), yet questions about how the mutated gene causes disease remain unanswered.

17 Mar 2011

U-M purchases Fluxion's IonFlux system to study nanoscale membrane disruption

Fluxion Biosciences, Inc. announced today that the University of Michigan Department of Chemistry has purchased the IonFlux 16 automated patch clamp instrument.

From Fluxion Biosciences 16 Mar 2011

Anavex to commence phase I clinical trial in Alzheimer’s disease

Anavex Life Sciences Corp. (“Anavex”) (OTCBB: AVXL) has announced that its clinical trial application (CTA) for ANAVEX 2-73, the company’s lead compound for Alzheimer’s disease, has been approved by the German regulatory health authority, BfArM. The Phase I trial of ANAVEX 2-73, which includes testing in healthy human volunteers, will commence immediately. In this Phase I program Anavex will assess the safety, maximally tolerated dose, pharmacokinetics and pharmacodynamics of ANAVEX 2-73.

15 Mar 2011

Challenge Problems in mathematical cardiology

Did you know that heart attacks can give you mathematics? That statement appears on the web site of James Keener, who works in the mathematics of cardiology. This area has many problems that are ripe for unified attack by mathematicians, clinicians, and biomedical engineers.

15 Mar 2011

Synta fourth-quarter total collaboration revenue decreases to $3.0 million

Synta Pharmaceuticals Corp., a biopharmaceutical company focused on discovering, developing, and commercializing small molecule drugs to treat severe medical conditions, today reported fourth-quarter and full-year 2010 financial results, provided an update on recent progress with its programs, and announced 2011 objectives.

11 Mar 2011

Redpoint Bio fourth quarter revenues are $0.7 million for 2010

Redpoint Bio Corporation, a company focused on the development of healthier foods and beverages and new approaches to the treatment of diabetes and obesity, today announced financial and operational results for the quarter and year ended December 31, 2010.

5 Mar 2011

MicroConstants completes installation, qualification of new Xevo TQ-S tandem mass spectrometer

MicroConstants, Inc., a bioanalytical and pharmacokinetic-specialty Contract Research Organization in San Diego, California, announces today that it has successfully completed the installation and qualification of a new Xevo TQ-S tandem mass spectrometer from Waters Corporation.

3 Mar 2011

Phase III trial results: Erlotinib has comparable efficacy to chemotherapy with better tolerability against lung cancer

The targeted cancer drug erlotinib has comparable efficacy to chemotherapy, and is better tolerated, in hard-to-treat cases where a patient's cancer has progressed quickly after treatment with first-line therapy, the results of a new phase III trial show.

27 Feb 2011

Preclinical data of Zalicus sodium channel compound published in journal PAIN

Zalicus Inc. today announced the publication of preclinical data in the journal PAIN. The paper describes the activity of Z212, a novel proprietary small organic compound that acts to modulate Nav1.7 and Nav1.8 sodium channels and to reduce neuropathic pain by targeting the hyper-excitability associated with chronic pain signaling pathways.

25 Feb 2011

PolyMedix completes PMX-30063 Phase 1 exposure-escalation clinical study to treat Staph infections

PolyMedix, Inc., an emerging biotechnology company focused on developing new therapeutic drugs to treat infectious diseases and acute cardiovascular disorders, today announced the successful completion of a Phase 1 exposure-escalation clinical study with its synthetic defensin-mimetic antibiotic, PMX-30063.

24 Feb 2011

Life Technologies announces winners of European Ion Torrent PGM Sequencer Grants Program

Life Technologies Corporation, today announced Dr. Angel Carracedo and Dr. Mark Pallen as the winners of the European Ion Torrent Personal Genome Machine (PGM™) Sequencer Grants Program.

19 Feb 2011

U.S. FDA posts public health communication about metal-on-metal hip implants use in THA

The U.S. Food and Drug Administration posted a public health communication this week about metal-on-metal hip components to notify the public of the concerns on the use of metal-on-metal hip components used in total hip arthroplasty.

18 Feb 2011

Sleeping Trojan horse technique resolves some difficulties in transporting metal ions into cells

A unique strategy developed by researchers at Cardiff University is opening up new possibilities for improving medical imaging.

18 Feb 2011

Registration open for idiopathic pulmonary fibrosis healthcare summit

The Pulmonary Fibrosis Foundation (PFF) announced today that registration is now open for the IPF Summit 2011: From Bench to Bedside. The conference will feature an innovative two-day continuing medical education (CME) program for physicians, researchers, and other health care professionals. Additionally there will be a separate one-day patient, family member, and caregiver program to address the growing educational needs of the idiopathic pulmonary fibrosis (IPF) community.

14 Feb 2011

Medical images on-call on new EXAM-PAD PC tablet for radiologists

Thanks to today's 3G telephone and WiFi technology, potentially life saving medical images (x-ray, CT, MRI, etc.) are now on-call—literally—anywhere and anytime for the benefit of medical care—and your doctor's personal business—with the revolutionary new EXAM-PAD PC tablet for radiologists introduced today by CoActiv Medical.

11 Feb 2011

Scientists discover new method for early diagnosis, treatment of plaque-related diseases

UC Santa Barbara scientists have made a discovery that has the potential for use in the early diagnosis and eventual treatment of plaque-related diseases such as Alzheimer's disease and Type 2 diabetes. Their work is published in a recent issue of Nature Chemistry.

10 Feb 2011

Single molecule FRET techniques combined with wavelet transforms give new view of AMPA receptor

A digital signal processing technique long used by statisticians to analyze data is helping Houston scientists understand the roots of memory and learning, Alzheimer's and Parkinson's diseases and stroke.

8 Feb 2011