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New treatment option could provide effective therapy for patients with dermatologic conditions

Alopecia areata, atopic dermatitis and vitiligo are highly visible dermatologic conditions that can have a negative effect on patients' quality of life and overall health. An emerging treatment option, however, could provide effective therapy for patients with these conditions.

3 Mar 2017

Research sheds new light on key factor involved in several diseases

New light on a key factor involved in diseases such as Parkinson's disease, gastric cancer and melanoma has been cast through latest University of Otago, New Zealand, research carried out in collaboration with Australian scientists.

28 Feb 2017

GUMC launches phase II clinical study to examine safety of cancer drug for Parkinson's disease

Georgetown University Medical Center today announces the launch of a phase II clinical trial to study the safety of the cancer drug nilotinib and its effects on clinical outcomes and biomarkers in people with Parkinson's disease.

27 Feb 2017

MGH researchers discover regulators of gene expression programs in medulloblastoma

Massachusetts General Hospital researchers have identified a mechanism that controls the expression of genes regulating the growth of the most aggressive form of medulloblastoma, the most common pediatric brain tumor. In their report published online in Cancer Discovery, the team also identifies potential targets for future treatments.

24 Feb 2017

Discovery of dual role played by PGK1 enzyme may indicate new therapeutic target for brain cancer

Discovery of a dual role played by the enzyme phosphoglycerate kinase 1 (PGK1) may indicate a new therapeutic target for glioblastoma, an often fatal form of brain cancer, according to researchers at The University of Texas MD Anderson Cancer Center.

24 Feb 2017

Researchers identify tumour protein that may hold key pancreatic cancer survival

A diagnosis of pancreatic cancer is often a death sentence because current chemotherapies have little impact on the disease.

24 Feb 2017

U of T study uncovers gene that may play key role in obesity

A University of Toronto (U of T) study on fruit flies has uncovered a gene that could play a key role in obesity in humans.

22 Feb 2017

Research may show new ways to repress inflammation at outset

Researchers at the University of Tübingen, working with colleagues in other parts of Germany and in the United States, have identified an enzyme as a kind of biological gauge regulating inflammation in the human body.

21 Feb 2017

Study provides insight into how microRNA may amplify effects of drug treatment in liver cancer

Treatment options for liver cancer are often limited and almost exclusively involve transplantation if possible, or local chemoembolization and radiofrequency ablation.

17 Feb 2017

New study confirms role of PAK4 protein in growth, spread of pancreatic cancer cells

A new study that confirms the role of a protein called PAK4 in the movement and growth of pancreatic cancer cells could help researchers find new ways to tackle the disease.

17 Feb 2017

Doctors use targeted molecular drugs to treat fatal cancerous blood syndromes

Genomic testing of biopsies from patients with deadly, treatment-resistant cancerous blood syndromes called histiocytoses allowed doctors to identify genes fueling the ailments and use targeted molecular drugs to successfully treat them.

16 Feb 2017

Study identifies protein in tumor microenvironment that promotes breast cancer spread

To understand what makes breast cancer spread, researchers are looking at where it lives - not just its original home in the breast but its new home where it settles in other organs. What's happening in that metastatic niche where migrated cancer cells are growing?

16 Feb 2017

Salk professor receives inaugural Sjöberg Prize for groundbreaking cancer research

Salk Professor Tony Hunter, who holds an American Cancer Society Professorship, has been awarded $500,000 as part of the $1 million Royal Swedish Academy of Sciences' inaugural Sjöberg Prize for Cancer Research for "groundbreaking studies of cellular processes that have led to the development of new and effective cancer drugs."

14 Feb 2017

Duke Health researchers identify potential new drug target for Huntington's disease

The loss of motor function and mental acuity associated with Huntington's disease might be treatable by restoring a cellular quality control process, which Duke Health researchers have identified as a key factor in the degenerative illness.

13 Feb 2017

New ‘release and kill’ strategy may shorten treatment periods for patients with tuberculosis

Mycobacterium tuberculosis has been called "the perfect pathogen." These bacteria hijack human macrophages, persist inside the cells to evade immune destruction, and then prevent the macrophage from undergoing programmed cell death.

8 Feb 2017

PERK protein could be target for development of new drugs for progressive supranuclear palsy

The brain disease "progressive supranuclear palsy" (PSP) is currently incurable and its symptoms can only be eased to a very limited degree. PSP impairs eye movements, locomotion, balance control, and speech.

6 Feb 2017

Scientists discover treatment that improves symptoms in mouse model of juvenile Batten disease

Researchers at Baylor College of Medicine, Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital and King's College London have discovered a treatment that improves the neurological symptoms in a mouse model of juvenile Batten disease.

6 Feb 2017

Kinase News and Research

New treatment option could provide effective therapy for patients with dermatologic conditions

Research sheds new light on key factor involved in several diseases

GUMC launches phase II clinical study to examine safety of cancer drug for Parkinson's disease

MGH researchers discover regulators of gene expression programs in medulloblastoma

Discovery of dual role played by PGK1 enzyme may indicate new therapeutic target for brain cancer

Researchers identify tumour protein that may hold key pancreatic cancer survival

U of T study uncovers gene that may play key role in obesity

Research may show new ways to repress inflammation at outset

Study provides insight into how microRNA may amplify effects of drug treatment in liver cancer

New study confirms role of PAK4 protein in growth, spread of pancreatic cancer cells

Doctors use targeted molecular drugs to treat fatal cancerous blood syndromes

Study identifies protein in tumor microenvironment that promotes breast cancer spread

Salk professor receives inaugural Sjöberg Prize for groundbreaking cancer research

Duke Health researchers identify potential new drug target for Huntington's disease

New ‘release and kill’ strategy may shorten treatment periods for patients with tuberculosis

PERK protein could be target for development of new drugs for progressive supranuclear palsy

Scientists discover treatment that improves symptoms in mouse model of juvenile Batten disease

Defects in key gene spur breast and ovarian cancer growth, study shows

Study reveals new mechanism that helps increase reductive power during high sugar intake

Researchers design antibody that recognizes and destroys blood cancer stem cells

Measuring Drug-Target Residence Times with Biochemical Assays eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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