Mass Spectrometry News and Research

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Mass spectrometry is an analytical method used to identify different compounds based on the atomic sample constitution of the molecules and their charge state, which enables “blind” analysis of an unknown sample without any prior knowledge of its composition.

Agena Bioscience expands ultrasensitive somatic mutation detection technology

Agena Bioscience, Inc., which recently acquired the Bioscience business of Sequenom, Inc., today announced expansion of the UltraSEEK™ technology, the first ultrasensitive somatic mutation detection technology for high-throughput and definitive interrogation of rare mutations that occur at less than 1% abundance in matched tissue, circulating plasma, and tumor samples.

31 May 2014

Agena Bioscience acquires Sequenom’s Bioscience business

Agena Bioscience, Inc., a portfolio company of Telegraph Hill Partners (THP), today acquired the Bioscience business of Sequenom, Inc., which sells the MassARRAY® System for mass spectrometry-based detection of nucleic acids in research and clinical laboratories.

31 May 2014

TSRI researchers discover key proteins involved in one type of DNA repair gone awry

Accumulation of DNA damage can cause aggressive forms of cancer and accelerated aging, so the body's DNA repair mechanisms are normally key to good health. However, in some diseases the DNA repair machinery can become harmful.

23 May 2014

Researchers discover key proteins involved in DNA repair gone awry

22 May 2014

Lucideon invests in an Agilent 7900 Quadrapole ICP-MS to extend its analysis techniques offerings

Lucideon, the international provider of materials development, testing and assurance, and formerly known as Ceram, is pleased to announce it has invested in the latest Agilent 7900 Quadrapole Inductively Coupled Plasma – Mass Spectrometry (ICP-MS).

From Lucideon 21 May 2014

New method for identifying bacteria in patient specimens leads to 92% cost reduction

Researchers at UNC Health Care have found that using a new method for identifying bacteria and fungi in patient specimens led to a 92 percent cost reduction in the reagents needed to run clinical microbiology tests.

21 May 2014

TSRI chemists develop correct structure of highly promising anticancer compound

Chemists at The Scripps Research Institute (TSRI) have determined the correct structure of a highly promising anticancer compound approved by the U.S. Food and Drug Administration (FDA) for clinical trials in cancer patients.

20 May 2014

Specific Technologies unveils SpecID blood culture system at General Meeting of the American Society for Microbiology

Specific Technologies, developer of the SpecID™ system to rapidly detect and identify bacterial species and strain via a metabolomic fingerprint, today announced that for the first time it will showcase its transformative SpecID blood culture system at the 114th General Meeting of the American Society for Microbiology, May 17-20, 2014 in Boston, Massachusetts at the Boston Convention and Exhibition Center.

16 May 2014

Anti-depressants could slow onset of Alzheimer's disease

A University of Pennsylvania researcher has discovered that the common selective serotonin reuptake inhibitor (SSRI) citalopram arrested the growth of amyloid beta, a peptide in the brain that clusters in plaques that are thought to trigger the development of Alzheimer's disease (AD).

15 May 2014

Antidepressant stops growth of plaques in mouse model of Alzheimer's disease

A commonly prescribed antidepressant can reduce production of the main ingredient in Alzheimer's brain plaques, according to new research at Washington University School of Medicine in St. Louis and the University of Pennsylvania.

15 May 2014

People who consume diet rich in resveratrol are likely to develop cardiovascular disease

A study of Italians who consume a diet rich in resveratrol — the compound found in red wine, dark chocolate and berries — finds they live no longer than and are just as likely to develop cardiovascular disease or cancer as those who eat or drink smaller amounts of the antioxidant.

13 May 2014

New paper offers new insights into role carcinoma-associated fibroblasts play in tumor biology

A new paper by a team of researchers led by Zachary T. Schafer, Coleman Assistant Professor of Cancer Biology in the Department of Biological Sciences at the University of Notre Dame, offers important new insights into the role carcinoma-associated fibroblasts (CAFs) play in tumor biology.

9 May 2014

Waters reports sales of $431 million for first quarter 2014

Waters Corporation reported today first quarter 2014 sales of $431 million, essentially flat versus sales of $430 million in the first quarter of 2013. In the quarter, the effect of foreign currency translation was neutral to sales growth.

29 Apr 2014

Scientists at Sheffield Hallam University receive major funding boost for animal-testing reduction project

Almost a quarter of a million pounds has been awarded to a team of scientists at Sheffield Hallam University to develop a new technique that will reduce the need for animal testing in pre-clinical research projects.

From Sheffield Hallam University 29 Apr 2014

Study finds role of oligomers in development of Parkinson's disease

Researchers at Aarhus University, Denmark, have drawn up the most detailed 'image of the enemy' to date of one of the body's most important players in the development of Parkinson's disease.

26 Apr 2014

Urine test separates nonadherent from treatment-resistant hypertensive patients

Researchers have used a urine test to show that about a quarter of patients with supposedly treatment-resistant hypertension are actually failing to take their medications as prescribed.

22 Apr 2014

Survey finds counterfeit and defective emergency contraceptives in Peru

A survey of emergency contraceptive pills in Peru found that 28 percent of the batches studied were either of substandard quality or falsified. Many pills released the active ingredient too slowly. Others had the wrong active ingredient. One batch had no active ingredient at all.

20 Apr 2014

Princeton professor receives Agilent Thought Leader Award to research on cellular metabolism activity

Agilent Technologies Inc. today announced that Joshua Rabinowitz, M.D., Ph.D., professor at Princeton University's Department of Chemistry and the Lewis-Sigler Institute for Integrative Genomics, has received an Agilent Thought Leader Award to support his work on quantitative analysis of cellular metabolism.

18 Apr 2014

Proteomics completes important milestone towards development of CDx test with validation of protein biomarkers

Proteomics now seeks a commercialisation partner to enter the RUO, LDT or IVD markets. Drug discovery company Proteomics International has completed an important milestone towards the development of a companion diagnostic (CDx) test with the validation of several of its protein biomarkers.

11 Apr 2014

AVEO joins with Biodesix to develop and commercialize ficlatuzumab for treatment of NSCLC

AVEO Oncology (NASDAQ: AVEO) and Biodesix, Inc. today announced that they have entered into a worldwide agreement to develop and commercialize AVEO's hepatocyte growth factor (HGF) inhibitory antibody ficlatuzumab, with a Biodesix® companion diagnostic test.

10 Apr 2014

Mass Spectrometry News and Research

Further Reading

Agena Bioscience expands ultrasensitive somatic mutation detection technology

Agena Bioscience acquires Sequenom’s Bioscience business

TSRI researchers discover key proteins involved in one type of DNA repair gone awry

Researchers discover key proteins involved in DNA repair gone awry

Lucideon invests in an Agilent 7900 Quadrapole ICP-MS to extend its analysis techniques offerings

New method for identifying bacteria in patient specimens leads to 92% cost reduction

TSRI chemists develop correct structure of highly promising anticancer compound

Specific Technologies unveils SpecID blood culture system at General Meeting of the American Society for Microbiology

Anti-depressants could slow onset of Alzheimer's disease

Antidepressant stops growth of plaques in mouse model of Alzheimer's disease

People who consume diet rich in resveratrol are likely to develop cardiovascular disease

New paper offers new insights into role carcinoma-associated fibroblasts play in tumor biology

Waters reports sales of $431 million for first quarter 2014

Scientists at Sheffield Hallam University receive major funding boost for animal-testing reduction project

Study finds role of oligomers in development of Parkinson's disease

Urine test separates nonadherent from treatment-resistant hypertensive patients

Survey finds counterfeit and defective emergency contraceptives in Peru

Princeton professor receives Agilent Thought Leader Award to research on cellular metabolism activity

Proteomics completes important milestone towards development of CDx test with validation of protein biomarkers

AVEO joins with Biodesix to develop and commercialize ficlatuzumab for treatment of NSCLC

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