Metastasis News and Research

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Metastasis is the spread of cancer from one part of the body to another. A tumor formed by cells that have spread is called a “metastatic tumor” or a “metastasis.” The metastatic tumor contains cells that are like those in the original (primary) tumor. The plural form of metastasis is metastases

Research findings may lead to new treatment option for ovarian cancer

A new study has identified an effective combination therapy for treating ovarian cancer cells.

31 Oct 2016

Fission yeast could help discover novel cancer drugs

Cancer is a notoriously difficult disease to treat. Not only do a wide variety of cancers exist, requiring specialized treatments for each type, but cancer cells within an individual can morph and render previously potent therapeutics ineffective.

24 Oct 2016

Rearrangement of collagen linked to poor outcomes in pancreatic cancer patients

A study in the current journal Oncotarget provides the first evidence linking a disturbance of the most common protein in the body with a poor outcome in pancreatic cancer.

21 Oct 2016

Research could lead to new type of treatment for pancreatic cancer based on gold nanoparticles

A diagnosis of pancreatic cancer is often a death sentence because chemotherapy and radiation have little impact on the disease.

19 Oct 2016

Researchers find new path to stop metastatic growth of cancer

Investigators from the Research Institute of the McGill University Health Centre, and the Institute of Cancer Research, London, have discovered that some cancer cells can draw blood from existing mature blood vessels allowing them to continue to spread.

18 Oct 2016

TUM scientists shed new light on metastases in the liver at early stage of pancreatic cancer

Pancreatic cancer is an exceptionally aggressive type of cancer. Frequently, metastases already start to grow in other organs, particularly often in the liver, before the original tumor was even detected.

7 Oct 2016

Researchers to explore potential roles of tumor-suppressor gene in kidney cancer

Renal cell carcinoma is the most common type of kidney cancer, and African-Americans and males appear most at risk for this disease that can be asymptomatic until it has spread and become highly lethal, said Dr. Vinata B. Lokeshwar, cancer researcher and chair of the Department of Biochemistry and Molecular Biology at the Medical College of Georgia at Augusta University.

7 Oct 2016

Combination therapy for melanoma has added benefit in certain patients

Nivolumab in combination with ipilimumab has been approved since May 2016 for adults with advanced melanoma. The German Institute for Quality and Efficiency in Health Care examined in a dossier assessment whether this drug offers an added benefit.

6 Oct 2016

Researchers aim to stop breast cancer metastasis from happening altogether

A new Tel Aviv University study finds that combining genetic therapy with chemotherapy delivered to a primary tumor site is extremely effective in preventing breast cancer metastasis.

5 Oct 2016

New type of nanoparticles can deliver chemotherapy efficiently to cancer cells

Engineering researchers at The University of Texas at Austin have developed a new method that delivers chemotherapy directly and efficiently to individual cells.

4 Oct 2016

HDAC inhibitors show potential to eliminate breast and ovarian cancer stem cells

A group of researchers, led by scientists at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, has shown that histone deacetylase (HDAC) inhibitors have the potential to eliminate stubborn reservoirs of breast and ovarian cancer stem cells (CSCs).

4 Oct 2016

University of Pennsylvania receives NSF grant to establish Center for Engineering Mechanobiology

The National Science Foundation has awarded the University of Pennsylvania a $24 Million, five-year grant to establish a Science and Technology Center focused on engineering mechanobiology, or the way cells exert and are influenced by the physical forces in their environment.

30 Sep 2016

TUM scientists discover molecular mechanism responsible for liver metastases at early stage

30 Sep 2016

Cell migration occurs by intermittent bursts of activity, researchers find

Cell migration is a central process in the development and maintenance of multicellular organisms.

29 Sep 2016

Bioactive compound from neem plant shows promising effects on prostate cancer

A team of international researchers led by Associate Professor Gautam Sethi from the Department of Pharmacology at the Yong Loo Lin School of Medicine at the National University of Singapore has found that nimbolide, a bioactive terpenoid compound derived from Azadirachta indica or more commonly known as the neem plant, could reduce the size of prostate tumour by up to 70 per cent and suppress its spread or metastasis by half.

29 Sep 2016

Study reveals radiosurgery as viable treatment option for patients with resected brain metastases

For patients who have cancer that has metastasized to the brain, stereotactic radiosurgery (SRS) results in statistically comparable survival rates, reduced cognitive decline and better quality of life (QOL), compared to whole brain radiotherapy (WBRT), according to research presented today at the 58th Annual Meeting of the American Society for Radiation Oncology.

26 Sep 2016

SRS reduces likelihood of local recurrence of brain metastases in cancer patients

Stereotactic radiosurgery (SRS) for cancer patients who receive the treatment for brain metastases decreases the likelihood of local recurrence but shows no positive difference in terms of overall survival (OS) or distant brain metastases (DBMs) rates, when compared to observation alone following surgical resection of brain metastases, according to research presented today at the 58th Annual Meeting of the American Society for Radiation Oncology.

26 Sep 2016

Researchers identify, validate three distinct molecular subtypes of prostate cancer

In the largest study of its kind to date, researchers have identified and validated three distinct molecular subtypes of prostate cancer that correlate with distant metastasis-free survival and can assist in future research to determine how patients will respond to treatment, according to research presented today at the 58th Annual Meeting of the American Society for Radiation Oncology.

26 Sep 2016

Magnetic bacteria can be promising vehicle for efficiently delivering tumor-fighting drugs

Researchers funded in part by the National Institute of Biomedical Imaging and Bioengineering have recently shown that magnetic bacteria are a promising vehicle for more efficiently delivering tumor-fighting drugs. They reported their results in the August 2016 issue of Nature Nanotechnology.

23 Sep 2016

Mount Sinai and TJU researchers awarded grant for UM research

Uveal melanoma (UM) is the second most common type of skin cancer. Approximately 50 percent of patients will develop metastasis or spread of their cancer, most commonly to the liver.

21 Sep 2016

Metastasis News and Research

Further Reading

Research findings may lead to new treatment option for ovarian cancer

Fission yeast could help discover novel cancer drugs

Rearrangement of collagen linked to poor outcomes in pancreatic cancer patients

Research could lead to new type of treatment for pancreatic cancer based on gold nanoparticles

Researchers find new path to stop metastatic growth of cancer

TUM scientists shed new light on metastases in the liver at early stage of pancreatic cancer

Researchers to explore potential roles of tumor-suppressor gene in kidney cancer

Combination therapy for melanoma has added benefit in certain patients

Researchers aim to stop breast cancer metastasis from happening altogether

New type of nanoparticles can deliver chemotherapy efficiently to cancer cells

HDAC inhibitors show potential to eliminate breast and ovarian cancer stem cells

University of Pennsylvania receives NSF grant to establish Center for Engineering Mechanobiology

TUM scientists discover molecular mechanism responsible for liver metastases at early stage

Cell migration occurs by intermittent bursts of activity, researchers find

Bioactive compound from neem plant shows promising effects on prostate cancer

Study reveals radiosurgery as viable treatment option for patients with resected brain metastases

SRS reduces likelihood of local recurrence of brain metastases in cancer patients

Researchers identify, validate three distinct molecular subtypes of prostate cancer

Magnetic bacteria can be promising vehicle for efficiently delivering tumor-fighting drugs

Mount Sinai and TJU researchers awarded grant for UM research

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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