Nicotine News and Research

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Nicotine is an alkaloid found in the nightshade family of plants (''Solanaceae'') which constitutes approximately 0.6–3.0% of dry weight of tobacco, with biosynthesis taking place in the roots, and accumulating in the leaves.

Safe vaccine protects mice against effects of cocaine

Researchers have produced a lasting anti-cocaine immunity in mice by giving them a safe vaccine that combines bits of the common cold virus with a particle that mimics cocaine.

5 Jan 2011

Researchers develop unique vaccine that produces long-lasting anti-cocaine immunity in mice

Researchers from The Scripps Research Institute, Weill Cornell Medical College, and Cornell University have produced a long-lasting anti-cocaine immunity in mice by giving them a unique vaccine that combines bits of the common cold virus with a particle that mimics cocaine.

5 Jan 2011

Vaccine blocks cocaine high in mice - human trials likely

Researchers have produced a lasting anti-cocaine immunity in mice by giving them a safe vaccine that combines bits of the common cold virus with a particle that mimics cocaine.

4 Jan 2011

Bupropion and varenicline help curb cigarette craving

The smoking cessation medications bupropion and varenicline may both be associated with changes in the way the brain reacts to smoking cues, making it easier for patients to resist cravings, according to two reports posted online today that will appear in the May print issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

4 Jan 2011

Free nicotine patches to help smokers quit this New Year

British smokers thinking of quitting have a reason to celebrate this New Year. Free nicotine patches are to be offered on the NHS as part of a major drive to help smokers quit. The Department of Health has announced that smokers would be given coupons for a week’s free trial of the patches in the “Quit kits”. The patches included in the kit will be either NiQuitin Clear 21mg patches or Nicotinell TTS 30 21mg/24 hour patches, Step 1.

29 Dec 2010

Ramius/RP Group extend tender offer to acquire Cypress Bioscience

Ramius V&O Acquisition LLC, affiliates of Ramius LLC (collectively, "Ramius") and affiliates of Royalty Pharma (together with Ramius and Purchaser, the "Ramius/RP Group") announced today that the Ramius/RP Group is extending its previously announced tender offer to acquire all of the outstanding shares of common stock of Cypress Bioscience, Inc., a pharmaceutical company engaged in the development of innovative drugs to treat central nervous system (CNS) disorders, until Midnight, January 5, 2011, unless the offer is otherwise extended.

22 Dec 2010

Smoking can increase pain severity in cancer patients

The relationship between smoking and cancer is well established. In a study published in the January 2011 issue of PAIN, researchers report evidence to suggest that cancer patients who continue to smoke despite their diagnosis experience greater pain than nonsmokers.

22 Dec 2010

Recent study finds racial and ethnic minority smokers of menthol cigarettes have lower quit rate

Menthol cigarettes may be harder to quit, particularly for some teens and African-Americans, who have the highest menthol cigarette use, according to a study by a team of researchers.

21 Dec 2010

Health-care coverage program for kids ends in Ariz.; Florida Medicaid patient information may be at risk

A new audit criticizes the Florida Agency for Health Care Administration and a contractor for failing to properly control access to computer systems that include sensitive information about Medicaid beneficiaries (Saunders, 12/17).

20 Dec 2010

Electronic cigarettes much safer than real cigarettes, says BUSPH researcher

In a new report that bucks the concerns raised by the Food and Drug Administration, a Boston University School of Public Health (BUSPH) (sph.bu.edu) researcher concludes that electronic cigarettes are much safer than real cigarettes and show promise in the fight against tobacco-related diseases and death.

17 Dec 2010

NIH grants $7.5 million for researchers to develop novel compounds in treating nicotine addiction

The Scripps Research Institute and the University of California, San Diego, School of Medicine have been awarded approximately $7.5 million over five years to develop novel compounds that could eventually become drug candidates for the treatment of nicotine dependence, and possibly other drug addictions.

16 Dec 2010

Apartment living exposes kids to more second-hand smoke

A new study finds that kids who live in apartments have more tobacco contaminants in their blood than those who live in houses, even if smokers in the household refrain from smoking at home.

13 Dec 2010

No safe level of exposure to secondhand smoke

The following is a statement by Cheryl G. Healton, DrPH, President and CEO of Legacy on the U.S. Surgeon General's Report:

13 Dec 2010

e-cigarettes – Debate rages around globe

Following misleading advice that ‘e-cigarettes’ are a “healthy way” to quit smoking, thousands of smokers are switching to these electronic cigarettes. According to the Australian Medical Association (AMA) and anti-smoking groups these smokeless, battery-powered e-cigarettes packed with nicotine have not been tested for safety and could pose a serious health risk. Electronic cigarettes contain an inhaler, an atomiser and nicotine suspended in propylene glycol and water. At present they are banned in NSW and Victoria but overseas suppliers sell them online.

12 Dec 2010

Exposure to tobacco smoke causes immediate damage leading to serious illness or death

Exposure to tobacco smoke - even occasional smoking or secondhand smoke - causes immediate damage to your body that can lead to serious illness or death, according to a report released today by U.S. Surgeon General Regina M. Benjamin. The comprehensive scientific report - Benjamin's first Surgeon General's report and the 30th tobacco-related Surgeon General's report issued since 1964 - describes specific pathways by which tobacco smoke damages the human body and leads to disease and death.

10 Dec 2010

Appeals Court upholds preliminary injunction against FDA to stop seizure of electronic cigarettes

In a straightforward decision, a Federal Appeals Court has upheld a preliminary injunction against the FDA to stop the seizure of the electronic cigarette as it enters the country to suppliers that retail them to the smoking public.

9 Dec 2010

e-cigarettes spark debate in U.S.

Electronic cigarettes have been seen as a tobacco product but not as drugs. The US Food and Drug Administration had appealed to the court to treat these cigarettes as drugs but the court says this is an oversight. The FDA cited five e-cigarette distributors for poor manufacturing practices and falsely claiming that the products help people stop smoking.

8 Dec 2010

Smoking cessation products available on PBS

Australia’s federal government has announced that it will subsidize the cost of nicotine patches to help smokers quit. The announcement was made by Health Minister Nicola Roxon on Thursday who said that concession card holders would be able to access Nicorette, Nicabate P and Nicotinell under the Pharmaceutical Benefits Scheme (PBS) from February 1, 2011. She said, “Cancer scars the lives of too many Australians and we know that reducing the smoking rate is one of the most effective ways to reduce the rate of death from this terrible disease.” Anti-smoking drug Varenicline (Champix) would also be available for willing quitters.

8 Dec 2010

Court ruling on regulation of electronic cigarettes as drugs and devices is wrong

A federal appeals court ruling today that the U.S. Food and Drug Administration (FDA) cannot regulate electronic cigarettes as drugs and devices is wrong on the law, wrong on the facts and fails to take into account the harmful implications of this decision for public health. This decision will allow any manufacturer to put any level of nicotine in any product and sell it to anybody, including children, with no government regulation or oversight at the present time. We urge the government to appeal this ruling.

8 Dec 2010

Integrating smoking cessation treatment with mental health care improves abstinence rates in PTSD veterans

Among smokers with military-related posttraumatic stress disorder (PTSD), integrating smoking cessation treatment with mental health care for PTSD resulted in higher rates of prolonged smoking abstinence, compared to referral for assistance with quitting smoking, according to a study in the December 8 issue of JAMA.

8 Dec 2010

Nicotine News and Research

Further Reading

Safe vaccine protects mice against effects of cocaine

Researchers develop unique vaccine that produces long-lasting anti-cocaine immunity in mice

Vaccine blocks cocaine high in mice - human trials likely

Bupropion and varenicline help curb cigarette craving

Free nicotine patches to help smokers quit this New Year

Ramius/RP Group extend tender offer to acquire Cypress Bioscience

Smoking can increase pain severity in cancer patients

Recent study finds racial and ethnic minority smokers of menthol cigarettes have lower quit rate

Health-care coverage program for kids ends in Ariz.; Florida Medicaid patient information may be at risk

Electronic cigarettes much safer than real cigarettes, says BUSPH researcher

NIH grants $7.5 million for researchers to develop novel compounds in treating nicotine addiction

Apartment living exposes kids to more second-hand smoke

No safe level of exposure to secondhand smoke

e-cigarettes – Debate rages around globe

Exposure to tobacco smoke causes immediate damage leading to serious illness or death

Appeals Court upholds preliminary injunction against FDA to stop seizure of electronic cigarettes

e-cigarettes spark debate in U.S.

Smoking cessation products available on PBS

Court ruling on regulation of electronic cigarettes as drugs and devices is wrong

Integrating smoking cessation treatment with mental health care improves abstinence rates in PTSD veterans

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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