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Repeat intraocular corticosteroid injections improve vision in people with persistent or recurrent uveitic macular edema

Repeat treatment with corticosteroid injections improved vision in people with persistent or recurrent uveitis-related macular edema better than two other therapies, according to results from a clinical trial funded by the National Eye Institute.

13 Jun 2023

Study reveals alarming pediatric antibiotic prescribing practices in Madagascar, Senegal, and Cambodia

In a recent article published in the journal PLOS Medicine, researchers performed a prospective, longitudinal study to estimate the proportion of outpatient consultations resulting in inappropriate antibiotic prescriptions in young children in three low- and middle-income countries (LMICs), Madagascar, Senegal, and Cambodia.

13 Jun 2023

Letermovir: A promising breakthrough in CMV prevention for kidney transplant recipients

In a recent article published in the journal JAMA Network, researchers performed a randomized clinical trial (RCT) to demonstrate the noninferiority of letermovir vs. valganciclovir for prophylaxis of cytomegalovirus (CMV) in adult CMV-seronegative kidney transplant recipients (KTRs) who received a kidney from a CMV-seropositive individual.

13 Jun 2023

Metformin shows promising antiviral activity against SARS-CoV-2

Metformin, a widely available oral medication, reduces SARS-CoV-2 viral load by 3.6-fold in outpatient trial, offering a potential treatment option. Ivermectin and fluvoxamine show no significant virologic effect.

12 Jun 2023

Metformin reduces risk of long COVID by over 40%

Researchers discuss whether metformin, ivermectin, or fluvoxamine could reduce the risk of long COVID if administered shortly after infection.

12 Jun 2023

Dental therapists help patients in need of care avoid the brush-off

All six of Michelle Ehlert’s children have Medicaid plans that should cover their dental care. But for years, she and her husband paid for dental care out-of-pocket — sometimes thousands of dollars a year.

9 Jun 2023

Impact of orally administered cannabidiol (CBD) on fitness and health among healthy adult individuals

Researchers evaluated the effects of oral CBD administration on the health and fitness of healthy adults.

9 Jun 2023

Gut health boost: Functional foods and herbs show promise in tackling SARS-CoV-2 variants

Functional foods and natural herbs have the potential to enhance immune function and maintain gut microbiota diversity. This review explores their role in mitigating the impact of SARS-CoV-2 variants on gut health and overall well-being.

8 Jun 2023

Study may help advance data on oncolytic adenovirus mediated double suicide-gene therapy for high-grade brain tumors

Researchers in the Hermelin Brain Tumor Center at Henry Ford Health are leading a Phase I clinical trial studying the maximum tolerated dose of an oncolytic adenovirus, a mutated virus engineered to selectively replicate in and destroy cancer tissue, in combination with fractionated stereotactic radiosurgery among patients who are undergoing resection of a recurrent high-grade astrocytoma brain tumor.

8 Jun 2023

Insilico Medicine nominates pan-TEAD inhibitor as a potential solution for drug resistance in solid tumor patients

Insilico Medicine, a generative artificial intelligence (AI)-driven clinical-stage drug discovery company, today announced the nomination of ISM6331, a potential best-in-class pan-TEAD inhibitor, as a preclinical candidate compound (PCC) generated by Chemistry42, its proprietary generative chemistry-driven molecule design engine, targeting the Hippo pathway for the treatment of advanced solid tumors.

8 Jun 2023

Newly discovered bacterial species can have a major role in causing tooth decay

Collaborating researchers from the University of Pennsylvania School of Dental Medicine and the Adams School of Dentistry and Gillings School of Global Public Health at the University of North Carolina have discovered that a bacterial species called Selenomonas sputigena can have a major role in causing tooth decay.

8 Jun 2023

Shifting towards precision medicine for type 2 diabetes dietary management

Researchers reviewed existing data on the genetic factors and the gene-diet interactions that could alter dietary management of type 2 diabetes.

8 Jun 2023

New process can help to design drugs with fewer or no side effects

Have you ever wondered how drugs reach their targets and achieve their function within our bodies? If a drug molecule or a ligand is a message, an inbox is typically a receptor in the cell membrane.

7 Jun 2023

Promising targeted therapy offers new hope to certain patients with advanced pancreatic cancer

A promising new targeted cancer therapy will soon be available to certain patients with advanced pancreatic cancer – from the comfort of their home.

7 Jun 2023

How does attention dysregulation impact anxiety, cognition, and low mood among adolescents?

Researchers explored the effects of attention dysregulation on anxiety, cognition, and low mood.

7 Jun 2023

Oral semaglutide outperforms other medications in type 2 diabetes treatment, significantly reducing HbA1c and body weight

Orally administered semaglutide shows significant efficacy in reducing HbA1c and body weight in patients with type 2 diabetes compared to other treatments. The study includes a large number of participants from multiple trials.

7 Jun 2023

CBD and EPA cream: Dynamic duo for youthful skin

What role did children play in household viral transmission during the COVID-19 pandemic, when enveloped virus rates were low, and relative proportions of COVID-19 were high?

Researchers performed a cohort study on a voluntary group in the United States.

6 Jun 2023

Oral News and Research

Repeat intraocular corticosteroid injections improve vision in people with persistent or recurrent uveitic macular edema

Study reveals alarming pediatric antibiotic prescribing practices in Madagascar, Senegal, and Cambodia

Letermovir: A promising breakthrough in CMV prevention for kidney transplant recipients

Metformin shows promising antiviral activity against SARS-CoV-2

Metformin reduces risk of long COVID by over 40%

Dental therapists help patients in need of care avoid the brush-off

Impact of orally administered cannabidiol (CBD) on fitness and health among healthy adult individuals

Gut health boost: Functional foods and herbs show promise in tackling SARS-CoV-2 variants

Study may help advance data on oncolytic adenovirus mediated double suicide-gene therapy for high-grade brain tumors

Insilico Medicine nominates pan-TEAD inhibitor as a potential solution for drug resistance in solid tumor patients

Newly discovered bacterial species can have a major role in causing tooth decay

Shifting towards precision medicine for type 2 diabetes dietary management

New process can help to design drugs with fewer or no side effects

Promising targeted therapy offers new hope to certain patients with advanced pancreatic cancer

How does attention dysregulation impact anxiety, cognition, and low mood among adolescents?

Oral semaglutide outperforms other medications in type 2 diabetes treatment, significantly reducing HbA1c and body weight

CBD and EPA cream: Dynamic duo for youthful skin

The phenolic composition, antioxidant capacity, and other functional properties of fresh and dried figs

Vaginal microbial diversity and pregnancy outcomes

What role did children play in household viral transmission during the COVID-19 pandemic, when enveloped virus rates were low, and relative proportions of COVID-19 were high?

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