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Extended-release naltrexone appears to help HIV-positive patients reduce heavy drinking

Extended-release naltrexone -- an injection that decreases heavy drinking in the general population when taken in conjunction with counseling -- appears to help HIV-positive individuals reduce their number of heavy drinking days too, say Yale researchers.

7 Aug 2018

New CAR T-cell immunotherapy trial targets solid tumors

Seattle Children's has opened a chimeric antigen receptor (CAR) T-cell immunotherapy trial for children and young adults with relapsed or refractory non-central nervous system EGFR-expressing solid tumors. In the phase 1 trial, STRIvE-01, cancer-fighting CAR T cells will target the EGFR protein expressed in many childhood sarcoma, kidney and neuroblastoma tumors.

7 Aug 2018

Scientists develop a way to deliver curcumin as an anti-cancer agent

Researchers have developed a way of delivering curcumin so that it can be effective as a therapeutic agent for cancer.

7 Aug 2018

New test method offers more reliable diagnosis of diabetes insipidus

When people produce excessive amounts of urine - more than three litres each day in adults is considered too much - doctors often find it difficult to establish a diagnosis under certain circumstances.

7 Aug 2018

Study: Potential new class of drugs may lower heart disease risk by targeting gut microbes

Cleveland Clinic researchers have designed a potential new class of drugs that may reduce cardiovascular risk by targeting a specific microbial pathway in the gut.

7 Aug 2018

Researchers identify role of infection-fighting cells in inflamed and damaged tissue

Hookworms infect nearly 430 million people in the world, mostly in countries where sanitation is poor, and people often walk barefoot.

7 Aug 2018

Researchers find ways to render curcumin soluble and deliver it to infected tumors

In India and other countries in Southeast Asia, curcumin is often used as a spice in cooking, particularly chicken or fish. It is known for its therapeutic effect and as a way to kill germs present in raw meet.

7 Aug 2018

Inhibition of NOVA1 gene helps prevent growth of lung cancer tumors

Researchers have identified a gene that when inhibited or reduced, in turn, reduced or prevented human non-small cell lung cancer tumors from growing.

7 Aug 2018

Scientists study effects of phototherapy on cardiovascular system

Light therapy is used to treat sleep disorders, depression, and seasonal mental disorders. In order to study its effects on the cardiovascular system and to make phototherapy safer for patients suffering from hypertension, experts from RUDN University were carrying out experiments on rats for five months.

7 Aug 2018

CPM for knee or shoulder surgery patients: Benefit applies only to two therapeutic indications

Patients who have had knee or shoulder surgery or who require conservative treatment can benefit from training with motor-driven continuous passive motion devices.

6 Aug 2018

Clinical trial to use stem cell transplants for treating Crohn's disease

A clinical trial has begun which will use stem cell transplants to grow a new immune system for people with untreatable Crohn's disease - a painful and chronic intestinal disease which affects at least 115,000 people in the UK.

6 Aug 2018

Snapchat dysmorphia - 'selfie-face' aspirations see rise in plastic surgery requests

Snapchat and Facetune as well as other social media apps come under fire in a new JAMA article. These apps are being increasingly used, causing more and more youngsters to alter and edit their faces to modify their actual appearance.

6 Aug 2018

Understanding the role of inflammatory cytokines in creating T cell exhaustion in cancer

A better understanding of the role secreted inflammatory cytokines play in the tumor microenvironment that results in the differentiation of effector T cells into exhausted T cells points to possible approaches to improve the antitumor activity of T cells and to intervene in T cell exhaustion.

3 Aug 2018

Wireless Vital Signs Monitor tracks critical health information in warfighters and civilians

A technology designed to treat injured warfighters on the battlefield is proving its worth to civilian emergency-response teams.

3 Aug 2018

Discovery of new epithelial lung cell type may affect cystic fibrosis therapy

Scientists have discovered a new type of cell in the human respiratory tract called the pulmonary ionocyte, and linked it to cystic fibrosis.

3 Aug 2018

Transgender individuals may be at higher risk for cardiovascular disease

Transgender individuals may be at higher risk for myocardial infarction and death due to cardiovascular disease, according to several studies.

3 Aug 2018

Mushrooms from the Far East area could be used to design novel anti-cancer drugs

Mushrooms from the Far East area contain the natural chemical compounds, which could be used for the design of the novel drugs with highly specific anti-tumor activities and low-toxicity.

2 Aug 2018

Regenacy Pharmaceuticals partners with CMTA to advance ricolinostat for treating hereditary neuropathy

Regenacy Pharmaceuticals, LLC, a clinical-stage biopharmaceutical company developing breakthrough treatments for diabetic and other peripheral neuropathies, today announced a collaboration with the Charcot-Marie-Tooth Association, a registered non-profit organization serving the hereditary neuropathy patient community, to validate the role of HDAC6 in multiple forms of Charcot-Marie-Tooth disease and evaluate the efficacy of ricolinostat, a selective HDAC6 inhibitor, in animal models.

2 Aug 2018

Nanostructured sensor system offers active monitoring of brain aneurysm treatment

Implantation of a stent-like flow diverter can offer one option for less invasive treatment of brain aneurysms – bulges in blood vessels – but the procedure requires frequent monitoring while the vessels heal.

2 Aug 2018

Tumor suppressor gene PTEN may be potential Achilles heel for breast cancer cells

In an article published July 17, 2018 by Nature Communications, a highly collaborative team of researchers at the Medical University of South Carolina and Ohio State University report that normal breast cells can prevent successful radiation treatment of breast cancer due to dysregulation between tumor suppressors and oncogenes.

2 Aug 2018

Therapy News and Research

Extended-release naltrexone appears to help HIV-positive patients reduce heavy drinking

New CAR T-cell immunotherapy trial targets solid tumors

Scientists develop a way to deliver curcumin as an anti-cancer agent

New test method offers more reliable diagnosis of diabetes insipidus

Study: Potential new class of drugs may lower heart disease risk by targeting gut microbes

Researchers identify role of infection-fighting cells in inflamed and damaged tissue

Researchers find ways to render curcumin soluble and deliver it to infected tumors

Inhibition of NOVA1 gene helps prevent growth of lung cancer tumors

Scientists study effects of phototherapy on cardiovascular system

CPM for knee or shoulder surgery patients: Benefit applies only to two therapeutic indications

Clinical trial to use stem cell transplants for treating Crohn's disease

Snapchat dysmorphia - 'selfie-face' aspirations see rise in plastic surgery requests

Understanding the role of inflammatory cytokines in creating T cell exhaustion in cancer

Wireless Vital Signs Monitor tracks critical health information in warfighters and civilians

Discovery of new epithelial lung cell type may affect cystic fibrosis therapy

Transgender individuals may be at higher risk for cardiovascular disease

Mushrooms from the Far East area could be used to design novel anti-cancer drugs

Regenacy Pharmaceuticals partners with CMTA to advance ricolinostat for treating hereditary neuropathy

Nanostructured sensor system offers active monitoring of brain aneurysm treatment

Tumor suppressor gene PTEN may be potential Achilles heel for breast cancer cells

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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