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Scientists introduce combination approach to fight cancer

For efficient cancer therapy with few side effects, the active drug should selectively attain high concentration in the tumor. In the journal Angewandte Chemie, scientists have introduced a new approach, in which two synergistic drug components are combined into a dimer.

31 May 2018

UTSA scientists explore stuttering and develop new technology to optimize brain function

A team of researchers at The University of Texas at San Antonio received a two-year, $387,000 grant, from the National Institutes of Health (NIH), to develop technology that will identify brain activity patterns that contribute to stuttering and use that technology to train people how to optimize brain functions.

31 May 2018

New guideline for HER2 testing in breast cancer benefits patients and clinicians

Published today, a Focused Update to the American Society of Clinical Oncology/College of American Pathologists guideline for human epidermal growth factor receptor 2 (HER2) testing in breast cancer brings new levels of clarity that will benefit patients and clinical teams alike.

31 May 2018

FDA approves first oral medication for adults with moderately to severely active ulcerative colitis

The U.S. Food and Drug Administration today expanded the approval of Xeljanz (tofacitinib) to include adults with moderately to severely active ulcerative colitis. Xeljanz is the first oral medication approved for chronic use in this indication.

30 May 2018

Impaired maternal-fetal environment associated with lower survival after surgery in newborns with CHD

Children who undergo surgery for congenital heart disease have lower survival rates by three years of age if there are specific problems during fetal development, such as hypertension in the mother or the newborn being born preterm or small for gestational age.

30 May 2018

FDA-approved drug for lymphoma and leukemia may help treat common type of brain tumor

New Cleveland Clinic research shows for the first time that ibrutinib, an FDA-approved drug for lymphoma and leukemia, may also help treat the most common – and deadliest – type of brain tumor.

30 May 2018

Male thyroid cancer survivors face nearly 50% higher CVD risk than women, study suggests

Male thyroid cancer survivors have a nearly 50 percent higher risk of developing heart disease than women within five years of cancer diagnosis, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

30 May 2018

Radiotherapy drug used for treating rare neuroendocrine cancers can be safe, effective for patients

A radiotherapy drug that treats the rare neuroendocrine cancers pheochromocytoma and paraganglioma can be both effective and safe for patients, according to the findings of a multi-center trial led by researchers in the Abramson Cancer Center of the University of Pennsylvania.

30 May 2018

Scientists develop a new approach for efficient cancer therapy

For efficient cancer therapy with few side effects, the active drug should selectively attain high concentration in the tumor.

30 May 2018

Early-life seizures prematurely switch on key brain synapses related to autism

Early-life seizures prematurely switch on key synapses in the brain that may contribute to further neurodevelopmental delay in children with autism and other intellectual disabilities, suggests a new study from researchers at Penn Medicine published online in Cell Reports.

29 May 2018

Single spinal injection reverses chemotherapy-induced pain for months in mice

Researchers at University of California San Diego School of Medicine have found a new way to block a root cause of pain. The key is a naturally occurring protein called apolipoprotein A-I binding protein (AIBP). AIBP binds to toll-like receptor 4 (TLR4), a protein that sits on the surface of cells like an antenna, searching for signs of infection or tissue damage.

29 May 2018

Study: Sex hormone levels associated with increased risk of cardiovascular disease in older women

In an analysis of data collected from more than 2,800 women after menopause, Johns Hopkins researchers report new evidence that a higher proportion of male to female sex hormones was associated with a significant increased relative cardiovascular disease risk.

29 May 2018

Olfactory receptor in human bladder might prove useful for bladder cancer therapy, diagnosis

Researchers from Bochum have detected an olfactory receptor in the human bladder that might prove useful for bladder cancer therapy and diagnosis.

29 May 2018

New research could advance art therapy for treating neurological and psychiatric disorders

Studies conducted at the University of Vienna by Marie Curie fellow Matthew Pelowski have contributed to the formation of the Vienna Integrated Model of Art Perception, a holistic framework within which the multiple cognitive processes underlying art viewing can be systematically organised.

29 May 2018

Antimicrobial peptides are promising alternative for combatting antimicrobial resistance

Overuse of antibiotics has led to the spread of multi-resistant bacteria that do not respond to conventional treatments.

29 May 2018

Researchers identify novel target for bladder cancer

Researchers have identified an olfactory receptor in the human bladder that could prove useful in the diagnosis and treatment of bladder cancer.

29 May 2018

Genome dark matter provides clues to fighting prostate cancer

Through studying the dark matter of the human genome, a team from the University of Michigan has shed light on how the hormone androgen drives prostate cancer and suggested a potential target for future therapy.

28 May 2018

NIH summit presents recommendations to accelerate treatment development for Alzheimer's disease

Experts from government, academia, industry, non-profit organizations put forward recommendations that provide a roadmap for an integrated, multidisciplinary research agenda necessary to inform priorities for Alzheimer's disease and related dementias.

26 May 2018

Causes and treatment of acute heart failure vary by region, registry shows

Triggers of acute heart failure vary globally, according to late breaking results from the REPORT-HF registry presented today at Heart Failure 2018 and the World Congress on Acute Heart Failure, a European Society of Cardiology Congress.

26 May 2018

Researchers reveal potent new mechanism of action for treatment of IBD

Professor Akiyoshi Fukamizu's research group of Life Science Center for Survival Dynamics, University of Tsukuba, Eisai Co., Ltd. and its gastrointestinal business subsidiary EA Pharma Co., Ltd. have revealed a mechanism in which an analogue (ER-464195-01) of Eisai's in-house discovered E6007 inhibits integrin activation by dissociating interaction between calreticulin (CRT) and integrin α 4 (ITGA4), suppressing adhesion and infiltration of leukocytes overall.

25 May 2018

Therapy News and Research

Scientists introduce combination approach to fight cancer

UTSA scientists explore stuttering and develop new technology to optimize brain function

New guideline for HER2 testing in breast cancer benefits patients and clinicians

FDA approves first oral medication for adults with moderately to severely active ulcerative colitis

Impaired maternal-fetal environment associated with lower survival after surgery in newborns with CHD

FDA-approved drug for lymphoma and leukemia may help treat common type of brain tumor

Male thyroid cancer survivors face nearly 50% higher CVD risk than women, study suggests

Radiotherapy drug used for treating rare neuroendocrine cancers can be safe, effective for patients

Scientists develop a new approach for efficient cancer therapy

Early-life seizures prematurely switch on key brain synapses related to autism

Single spinal injection reverses chemotherapy-induced pain for months in mice

Study: Sex hormone levels associated with increased risk of cardiovascular disease in older women

Olfactory receptor in human bladder might prove useful for bladder cancer therapy, diagnosis

New research could advance art therapy for treating neurological and psychiatric disorders

Antimicrobial peptides are promising alternative for combatting antimicrobial resistance

Researchers identify novel target for bladder cancer

Genome dark matter provides clues to fighting prostate cancer

NIH summit presents recommendations to accelerate treatment development for Alzheimer's disease

Causes and treatment of acute heart failure vary by region, registry shows

Researchers reveal potent new mechanism of action for treatment of IBD

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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