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PureTech Health collaborates with Roche to advance oral administration of antisense oligonucleotides

PureTech Health plc, a clinical-stage biopharmaceutical company developing novel medicines focused on the Brain-Immune-Gut Axis, today announced that it has entered into a multiyear collaboration with F. Hoffmann-La Roche Ltd and Hoffmann-La Roche Inc., to advance PureTech's milk-derived exosome platform technology for the oral administration of Roche's antisense oligonucleotide platform.

20 Jul 2018

Ferring announces FDA approval of ZOMACTON for injection in four new pediatric indications

Ferring Pharmaceuticals Inc. today announced that the U.S. Food and Drug Administration has approved ZOMACTON for injection in four additional pediatric indications

20 Jul 2018

Genetic sequencing reveals new clues to aggressiveness of prostate cancer

Using genetic sequencing, scientists have revealed the complete DNA makeup of more than 100 aggressive prostate tumors, pinpointing important genetic errors these deadly tumors have in common.

20 Jul 2018

UK health communication researcher seeks solutions for disposing leftover medicine

University of Kentucky health communication researcher Don Helme is partnering with the Kentucky Attorney General's office to gauge public opinion on a new drug deactivation pouch, part of a larger effort to develop solutions to the state's opioid epidemic.

20 Jul 2018

Using miniature drug-filled nanocarriers to target headaches and tumors

Scientists at the Mainz University Medical Center and the Max Planck Institute for Polymer Research have developed a new method to enable miniature drug-filled nanocarriers to dock on to immune cells, which in turn attack tumors.

20 Jul 2018

Researchers identify enzyme as potential new drug target for blood disorders

Medical researchers have identified a key signaling protein that regulates hemoglobin production in red blood cells, offering a possible target for a future innovative drug to treat sickle cell disease.

20 Jul 2018

Scientists move one step further in developing eye drops to treat age-related macular degeneration

Scientists at the University of Birmingham are one step closer to developing an eye drop that could revolutionize treatment for age-related macular degeneration.

20 Jul 2018

Top AI companies join hands to discover novel drugs for DMD

Insilico Medicine a leader in artificial intelligence for drug discovery, biomarker development and aging research, announced a research collaboration agreement with A2A Pharmaceuticals, Inc. A2A is a biotechnology company headquartered in New York and focused on development of novel drugs for unmet needs in oncology, drug resistant bacterial infections, and other life threatening diseases.

20 Jul 2018

Researchers to study molecular mechanisms behind susceptibility of males to autism

Neurodevelopmental disorders such as autism spectrum disorder and intellectual disability are more prevalent in males than females.

20 Jul 2018

ZHX2 protein could offer a new treatment strategy for kidney cancer

University of North Carolina Lineberger Comprehensive Cancer Center scientists have uncovered a potential therapeutic target for kidney cancers that have a common genetic change.

20 Jul 2018

New discovery could save millions of lives from fatal fungal infections

Life-threatening fungal infections affect more than two million people worldwide. Effective antifungal medications are very limited.

20 Jul 2018

ADHD medications may fail to improve cognition in healthy college students, study shows

Contrary to popular belief across college campuses, attention deficit hyperactivity disorder medications may fail to improve cognition in healthy students and actually can impair functioning, according to a study by researchers at the University of Rhode Island and Brown University.

20 Jul 2018

Podcast: KHN’s ‘What the Health?’ Drug prices and unicorns

A trio of court actions provide news for this week's “What the Health?'” panel. A federal appeals court this week handed hospitals a setback in their effort to stop the Trump administration from cutting funding for a program that provides deep discounts on drugs.

19 Jul 2018

Phase 3 study of tanezumab in patients with osteoarthritis pain meets all three co-primary endpoints

Pfizer Inc. and Eli Lilly and Company today announced that a 16-week Phase 3 study in patients with osteoarthritis pain evaluating subcutaneous administration of tanezumab, an investigational humanized monoclonal antibody, met all three co-primary endpoints.

19 Jul 2018

Biophysicists use infrared sensor as new method for drug discovery

Using an infrared sensor, biophysicists at Ruhr-Universität Bochum have succeeded in analyzing quickly and easily which active agents affect the structure of proteins and how long that effect lasts.

19 Jul 2018

TGen opens tissue donation portal to advance DIPG research

A tissue donation portal opened today at the Translational Genomics Research Institute (TGen), which will advance research towards new treatments for an aggressive brain cancer that mostly strikes young children.

19 Jul 2018

Study uncovers new protein complex that shields broken DNA ends

Scientists have made a major discovery about how cells repair broken strands of DNA that could have huge implications for the treatment of cancer.

19 Jul 2018

Understanding triple-negative breast cancer to develop better treatments

Breast cancer affects 1 in 8 women in her lifetime. Among the various types, triple-negative breast cancer is the rarest and most aggressive – affecting about 15 percent of breast cancer patients. It is also the least studied.

19 Jul 2018

Researchers unravel how ALL invades the central nervous system

A deadly feature of acute lymphoblastic leukemia is its invasion of the central nervous system.

19 Jul 2018

Scientists study adverse effects of carbon, silicon nanotubes and carbon nanofibers

Nanoparticles with a wide range of applying, including medicine, damage cells of microalgae Heterosigma akashivo badly. This algae species is widely spread in the Russian Far East marine area. The acute toxic effect exhibited at concentrations of 100 mg/l of carbon nanotubes and silicon nanotubes in the sea- or fresh water.

19 Jul 2018

Drugs News and Research

PureTech Health collaborates with Roche to advance oral administration of antisense oligonucleotides

Ferring announces FDA approval of ZOMACTON for injection in four new pediatric indications

Genetic sequencing reveals new clues to aggressiveness of prostate cancer

UK health communication researcher seeks solutions for disposing leftover medicine

Using miniature drug-filled nanocarriers to target headaches and tumors

Researchers identify enzyme as potential new drug target for blood disorders

Scientists move one step further in developing eye drops to treat age-related macular degeneration

Top AI companies join hands to discover novel drugs for DMD

Researchers to study molecular mechanisms behind susceptibility of males to autism

ZHX2 protein could offer a new treatment strategy for kidney cancer

New discovery could save millions of lives from fatal fungal infections

ADHD medications may fail to improve cognition in healthy college students, study shows

Podcast: KHN’s ‘What the Health?’ Drug prices and unicorns

Phase 3 study of tanezumab in patients with osteoarthritis pain meets all three co-primary endpoints

Biophysicists use infrared sensor as new method for drug discovery

TGen opens tissue donation portal to advance DIPG research

Study uncovers new protein complex that shields broken DNA ends

Understanding triple-negative breast cancer to develop better treatments

Researchers unravel how ALL invades the central nervous system

Scientists study adverse effects of carbon, silicon nanotubes and carbon nanofibers

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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