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Researchers shed light on how androgen deprivation therapy increases risk for cardiovascular mortality

Prostate cancer is the most common cancer in men in the US. As the prostate is a testosterone-responsive gland, androgen deprivation therapy is the cornerstone of treatment in these men, with approximately 50 percent of prostate cancer patients starting ADT within a year of diagnosis.

22 May 2018

Study: Medical centers more willing to perform lung transplants for severe alcoholic hepatitis patients

Increasingly, liver transplant centers are changing a long-standing practice of delaying potentially life-saving liver transplantation for patients with severe alcoholic hepatitis until after they stopped drinking alcohol for six months, according to a new study scheduled for presentation at Digestive Disease Week® (DDW) 2018.

22 May 2018

ToolGen's CRISPR/Cas9 gene editing platform improves T-cell anti-tumor activity in mouse model

ToolGen, Inc., a biotechnology company specializing in genome editing, today announced data demonstrating that blocking a molecular pathway that down-regulates T-cell activity with the Company’s CRISPR/Cas9 gene editing platform results in increased T-cell receptor signaling, in vitro, and in improved anti-tumor activity when tested against in a mouse glioblastoma tumor model.

22 May 2018

Celltrion Healthcare advocates early introduction of biologics for patients to improve clinical outcomes

At the International Society for Pharmacoeconomics and Outcomes Research 23rd Annual International Meeting in Baltimore, Celltrion Healthcare today advocated for healthcare systems to introduce biologics earlier in a patient’s treatment regimen in order to improve clinical outcomes.

22 May 2018

Proteins moderating nicotine dependence may help fat cells burn energy

The same proteins that moderate nicotine dependence in the brain may be involved in regulating metabolism by acting directly on certain types of fat cells, new research from the University of Michigan Life Sciences Institute shows.

22 May 2018

PSCK9 inhibitors may provide benefit to atherosclerosis patients with high lipoprotein(a) levels

Lipoprotein(a) is a variant of LDL (low-density lipoprotein) cholesterol, and large amounts of data have shown that higher lipoprotein(a) levels are associated with an increased risk of cardiovascular events.

22 May 2018

Novel drug prevents memory impairment in mice exposed to simulated deep space radiation

Planning a trip to Mars? You'll want to remember your anti-radiation pills. NASA and private space companies like SpaceX plan to send humans to the red planet within the next 15 years--but among the major challenges facing future crewed space missions is how to protect astronauts from the dangerous cosmic radiation of deep space.

22 May 2018

FDA approves new drug to treat thrombocytopenia in adults with chronic liver disease

The U.S. Food and Drug Administration today approved Doptelet (avatrombopag) tablets to treat low blood platelet count (thrombocytopenia) in adults with chronic liver disease who are scheduled to undergo a medical or dental procedure. This is the first drug approved by the FDA for this use.

22 May 2018

Thyroid tumors may be more susceptible to precisely targeted radiation treatment, suggests study

Anaplastic thyroid cancer is almost uniformly fatal, with an average lifespan of about 5 months after diagnosis.

22 May 2018

Treg infusions show promise in slowing progression of ALS

Recent research from Houston Methodist Hospital showed that a new immunotherapy was safe for patients with ALS and also revealed surprising results that could bring hope to patients who have this relentlessly progressive and fatal disease.

21 May 2018

Researchers create tool to determine patient's response to immunotherapy drugs

Understanding that not all bladder cancers are the same, researchers at the University of North Carolina Lineberger Comprehensive Cancer Center have created a tool that may help them to uncover why only a fraction of patients respond to new immune-based treatments.

21 May 2018

Researchers discover new disease mechanism in chronic tobacco smokers

Research published in the journal Clinical Science suggests that an immune signaling protein called interleukin-26 is increased among chronic smokers with lung disease and this involvement reveals disease mechanisms of interest for developing more effective therapy for these hard-to-treat patients.

21 May 2018

ACR urges legislative action on access and cost barriers in rheumatologic care

Rheumatologists and rheumatology health professionals convened on Capitol Hill this week to urge legislative action on pressing policy issues affecting rheumatology care during the American College of Rheumatology's Advocacy Leadership Conference, held May 16-17, 2018 in Washington, D.C.

21 May 2018

Analysis of lymph node dissection shows no overall survival benefit in renal carcinoma patients

An analysis of lymph node dissection in renal cell carcinoma that has not spread to other organs indicates the procedure is often performed for stage 1 disease and shows no overall survival benefit.

21 May 2018

Unique nanotechnology method to simplify skin disease diagnosis

In a new SLAS Technology auto-commentary, two authors of an article recently published in Nature Biomedical Engineering ("Abnormal Scar Identification with Spherical Nucleic Acid Technology" – www.nature.com/articles/s41551-018-0218-x) share more insight into their unique method for skin disease diagnosis using NanoFlare nanotechnology.

21 May 2018

Researchers use MR spectroscopy to investigate mechanisms behind targeted treatment for gliomas

Using a novel imaging method, a Massachusetts General Hospital research team is investigating the mechanisms behind a potential targeted treatment for a subtype of the deadly brains tumors called gliomas.

21 May 2018

Clinical study supports usual medical care plus chiropractic care for low back pain

U.S military personnel with low back pain who received usual medical care plus chiropractic care reported moderate improvement in their pain intensity and disability compared with patients who received usual medical care alone.

18 May 2018

Novel IR imaging offers rapid and reliable analysis of cancer tissues

Researchers at Ruhr-Universität Bochum have deployed a novel infrared (IR) microscope with quantum cascade lasers in order to analyze tissue samples taken during routine clinical procedures for colorectal cancer diagnosis.

From Daylight Solutions Inc 18 May 2018

New CRISPR/Cas9 system targets regulatory genes of AIDS virus

By destroying the regulatory genes of the AIDS virus HIV-1 using the genome editing system CRISPR/Cas9, a Japanese research group has succeeded in blocking the production of HIV-1 by infected cells.

18 May 2018

Gene therapy that reverses blindness in dogs could also help treat humans

A Michigan State University veterinary ophthalmologist has modified a gene therapy that reverses blindness in dogs that have a certain form of a disease known as progressive retinal atrophy, or PRA, and is now looking to advance the treatment for human use.

18 May 2018

Therapy News and Research

Researchers shed light on how androgen deprivation therapy increases risk for cardiovascular mortality

Study: Medical centers more willing to perform lung transplants for severe alcoholic hepatitis patients

ToolGen's CRISPR/Cas9 gene editing platform improves T-cell anti-tumor activity in mouse model

Celltrion Healthcare advocates early introduction of biologics for patients to improve clinical outcomes

Proteins moderating nicotine dependence may help fat cells burn energy

PSCK9 inhibitors may provide benefit to atherosclerosis patients with high lipoprotein(a) levels

Novel drug prevents memory impairment in mice exposed to simulated deep space radiation

FDA approves new drug to treat thrombocytopenia in adults with chronic liver disease

Thyroid tumors may be more susceptible to precisely targeted radiation treatment, suggests study

Treg infusions show promise in slowing progression of ALS

Researchers create tool to determine patient's response to immunotherapy drugs

Researchers discover new disease mechanism in chronic tobacco smokers

ACR urges legislative action on access and cost barriers in rheumatologic care

Analysis of lymph node dissection shows no overall survival benefit in renal carcinoma patients

Unique nanotechnology method to simplify skin disease diagnosis

Researchers use MR spectroscopy to investigate mechanisms behind targeted treatment for gliomas

Clinical study supports usual medical care plus chiropractic care for low back pain

Novel IR imaging offers rapid and reliable analysis of cancer tissues

New CRISPR/Cas9 system targets regulatory genes of AIDS virus

Gene therapy that reverses blindness in dogs could also help treat humans

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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