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Scientists discover new way to inhibit growth of glioblastoma

Scientists have found a way to inhibit the growth of glioblastoma, a type of brain cancer with low survival rates, by targeting a protein that drives growth of brain tumors, according to research from the Peter O'Donnell Jr. Brain Institute and Harold C. Simmons Comprehensive Cancer Center.

25 Jan 2017

TSRI scientists receive $1.8 million grant to develop drug candidates for multiple diseases

Scientists from the Florida campus of The Scripps Research Institute have been awarded approximately $1.8 million from the National Institute of General Medical Sciences of the National Institutes of Health to develop a series of drug candidates for a number of diseases, including heart disease, rheumatoid arthritis and several neurodegenerative disorders.

24 Jan 2017

Researchers uncover mechanism of resistance used by triple negative breast cancer

Breast cancer cells are evasive, finding ways to bypass drugs designed to stop their unchecked growth.

20 Jan 2017

Mayo Clinic researchers identify genetic promoter that drives lung cancer formation

Researchers at Mayo Clinic have identified a genetic promoter of cancer that drives a major form of lung cancer.

19 Jan 2017

Stem cell research offers alternative view of cancer metastasis

Stem cells are among the most energetically activated, migratory and proliferative sub-populations of tumour cells, according to observations by scholars at the Biomedical Research Centre at the University of Salford.

18 Jan 2017

Novel treatment can effectively inhibit development of GVHD in mice, study shows

Graft-versus-host-disease (GVHD) is the leading cause of non-relapse associated death in patients who receive stem cell transplants.

12 Jan 2017

Researchers identify new subgroup of cervical cancers with different genetic features

A team of University of South Carolina scientists led by Carolyn Banister and Phillip Buckhaults has identified a new subtype of cervical cancer that, like most cervical cancers, is triggered by human papillomavirus (HPV) but whose growth is not directed by the virus, suggesting that therapy targeting these tumors' distinct genomic pathways may improve patient outcomes over standard treatment.

11 Jan 2017

KIT researchers prove that neurons regulate blood vessel growth

A team of researchers at Karlsruhe Institute of Technology shake at the foundations of a dogma of cell biology.

10 Jan 2017

Researchers discover new natural tooth repair method using Alzheimer's drug

A new method of stimulating the renewal of living stem cells in tooth pulp using an Alzheimer's drug has been discovered by a team of researchers at King's College London.

9 Jan 2017

The 10th annual symposium at UC Riverside focuses on glial-neuronal interactions in health and disease

The brain is home to two kinds of cells: neurons and glia, with the latter protecting the former. Glia, the stuff between neurons, are important also because they regulate and define neuron-neuron communication.

9 Jan 2017

New research suggests novel combination approach to fight against gliomas

"Devastating" and "dismal." That's how leading researchers describe the present outlook for malignant brain tumors. The median survival rate for patients with glioblastoma multiforme, or GBM, is a mere 14.2 months.

4 Jan 2017

How does the brain control appetite?

Energy balance between energy intake and expenditure in our bodies is important for maintaining energy homeostasis to keep our bodies functioning properly. The appetite determines how much we eat, the energy intake, by communication between the brain and body.

4 Jan 2017

BUSM professor receives Ellison Foundation grant to explore new Parkinson's disease target

Richard Myers, PhD, professor of neurology at Boston University School of Medicine, was recently awarded $100,000 from the Ellison Foundation for research to further study a Parkinson's disease (PD) target.

4 Jan 2017

AMPK enzyme plays vital role in enhancing muscle insulin sensitivity after physical activity

ampk Physical activity benefits diabetics and others with insulin resistance. One of the reasons is that a single bout of physical activity increases the effectiveness of insulin.

3 Jan 2017

Sirt1 plays key role in regenerating glial progenitor cells after hypoxia-induced brain injury in preemies

Developing brains in newborns have a sizable pool of a certain type of immature progenitor cell that can be expanded and induced to replace cells lost to brain injury.

19 Dec 2016

Research finds link between p53 pathway and ribosome biogenesis, nucleotide metabolism in DBA

Diamond Blackfan Anemia (DBA) is a condition that is characterized by a failure of the bone marrow to produce red blood cells, congenital abnormalities, and a predisposition to cancer.

17 Dec 2016

Researchers pinpoint mechanism underlying astrocyte-mediated recovery of brain tissue after injury

A Kobe University research team has pinpointed the mechanism underlying astrocyte-mediated restoration of brain tissue after an injury. This could lead to new treatments that encourage regeneration by limiting damage to neurons incurred by reduced blood supply or trauma.

15 Dec 2016

Leukaemia patients could safely reduce side effects of drug by cutting dose in half, study shows

Patients with a chronic type of leukaemia could safely reduce the side effects of life-long treatment by cutting their dose in half, according to the results of a University of Liverpool led study presented at an international conference in America this week.

6 Dec 2016

UC San Diego scientists reveal surprising role for Hippo pathway in subduing tumor immunogenicity

Previous studies identified the Hippo pathway kinases LATS1/2 as a tumor suppressor, but new research led by University of California San Diego School of Medicine scientists reveals a surprising role for these enzymes in subduing cancer immunity. The findings, published in Cell on December 1, could have a clinical role in improving efficiency of immunotherapy drugs.

1 Dec 2016

Research provides insights into how molecular adaptations can lead to differential circadian timing

The non-biting marine midge Clunio marinus lives along Europe's tide-shapen coasts, where precise timing is of existential importance: Reproduction and oviposition must occur when the tide is at its lowest.

24 Nov 2016

Kinase News and Research

Scientists discover new way to inhibit growth of glioblastoma

TSRI scientists receive $1.8 million grant to develop drug candidates for multiple diseases

Researchers uncover mechanism of resistance used by triple negative breast cancer

Mayo Clinic researchers identify genetic promoter that drives lung cancer formation

Stem cell research offers alternative view of cancer metastasis

Novel treatment can effectively inhibit development of GVHD in mice, study shows

Researchers identify new subgroup of cervical cancers with different genetic features

KIT researchers prove that neurons regulate blood vessel growth

Researchers discover new natural tooth repair method using Alzheimer's drug

The 10th annual symposium at UC Riverside focuses on glial-neuronal interactions in health and disease

New research suggests novel combination approach to fight against gliomas

How does the brain control appetite?

BUSM professor receives Ellison Foundation grant to explore new Parkinson's disease target

AMPK enzyme plays vital role in enhancing muscle insulin sensitivity after physical activity

Sirt1 plays key role in regenerating glial progenitor cells after hypoxia-induced brain injury in preemies

Research finds link between p53 pathway and ribosome biogenesis, nucleotide metabolism in DBA

Researchers pinpoint mechanism underlying astrocyte-mediated recovery of brain tissue after injury

Leukaemia patients could safely reduce side effects of drug by cutting dose in half, study shows

UC San Diego scientists reveal surprising role for Hippo pathway in subduing tumor immunogenicity

Research provides insights into how molecular adaptations can lead to differential circadian timing

Exploring Strategies for Targeting Kinases in Innate Immunity eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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