Malignant News and Research

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Researchers identify small RNA molecule that promotes deadly forms of breast cancer

Researchers from Princeton University's Department of Molecular Biology have identified a small RNA molecule that helps maintain the activity of stem cells in both healthy and cancerous breast tissue.

23 May 2017

Researchers discover novel mechanism that causes malignant pleural effusion in lung cancer patients

Lung cancer patients are particularly susceptible to malignant pleural effusion, when fluid collects in the space between the lungs and the chest wall. Researchers at the Helmholtz Zentrum München, in partnership with the German Center for Lung Research, have discovered a novel mechanism that causes this to happen.

19 May 2017

Researchers develop new imaging technique to ensure complete removal of tumor during surgery

Of the quarter-million women diagnosed with breast cancer every year in the United States, about 180,000 undergo surgery to remove the cancerous tissue while preserving as much healthy breast tissue as possible.

18 May 2017

NIBIB-funded scientists develop rapid and accurate tool for detecting early pancreatic cancer

Researchers funded by the National Institute of Biomedical Imaging and Bioengineering (NIBIB) have developed a new tool for detecting early pancreatic cancer.

17 May 2017

Breast cancer cells undergo stiffening state prior to becoming malignant, study shows

A study published now on Nature Communications shows that breast cancer cells undergo a stiffening state prior to acquiring malignant features and becoming invasive.

16 May 2017

Study prompts further assessment of tomato extracts’ use in gastric cancer prevention

A new study shows that whole tomato extracts from two different Southern Italy cultivars inhibit gastric cancer cell growth and malignant features, paving the way for future studies aimed at implementing lifestyle habits not only for prevention but potentially as a support to conventional therapies.

15 May 2017

Analyzing single-cell RNA data in pre-malignant tumors

RNA sequencing is basically the isolation of RNA from cells and the use of reverse transcriptase to turn the RNA into DNA. You can then use your standard DNA sequencing technologies to quantify the cDNA that you obtained from the reverse transcription reaction.

12 May 2017

Phase 1 trial shows safety and tolerability of oncolytic HSV-1 for children, young adults with cancer

HSV1716 – an oncolytic herpes simplex virus-1 – has been studied in adults via injection into the brain and superficial tumors.

11 May 2017

Study shows link between susceptibility to malignant hyperthermia and exertional heat stroke

New research published online in The FASEB Journal may ultimately help athletes and trainers better understand who may be more at risk for heat stroke.

11 May 2017

Vitamin A deficiency leads to loss of blood stem cells

Many specialized cells, such as in the skin, gut or blood, have a lifespan of only a few days. Therefore, steady replenishment of these cells is indispensable. They arise from so-called "adult" stem cells that divide continuously.

5 May 2017

Advanced endoscope to enable rapid, accurate diagnosis of early colon cancer

Minimally invasive endoscope using breakthrough photonics technology to enable rapid, accurate diagnosis of bowel polyps and early colon cancer.

5 May 2017

Heart failure patients have higher risk of death than people with common cancers

A study led by Keele University, in collaboration with the Universities of Aberdeen and Manchester, shows that men and women suffering from heart failure have a higher risk of death than people with most common types of cancer.

4 May 2017

Study finds worse survival rates for heart failure despite advances in treatment

A new analysis finds that, despite advances in care, men and women with a diagnosis of heart failure continue to have worse survival rates than patients with certain common cancers.

4 May 2017

Lethal DNA re-replication may be used to attack cancer cells

DNA over-replication is a phenomenon that can have devastating consequences for proliferating cells. When parts of the genome are duplicated more than once, cells suffer from 'genomic instability' (alterations to the structure, composition and/or number of chromosomes), and this process gives rise to aberrant cells as those detected in many carcinomas.

4 May 2017

Research sheds new light on surprising link between blood sugar and brain cancers

New research further illuminates the surprising relationship between blood sugar and brain tumors and could begin to shed light on how certain cancers develop.

3 May 2017

Researchers identify key player in initiation and progression of melanoma

Identification and functional validation of proteins involved in tumorigenesis are essential steps toward advancing cancer precision medicine. In The Journal of Clinical Investigation researchers from VIB, KU Leuven together with colleagues from INSERM now report the important role for FES in the initiation and progression of melanoma, a malignant type of skin cancer, that is notoriously quick to metastasize and that responds poorly to existing cancer treatments.

3 May 2017

Atomic Kitten Natasha Hamilton leads 'black henna' temporary tattoo warning

Atomic Kitten Natasha Hamilton is backing a British Skin Foundation campaign to #AvoidBlackHenna as summer approaches. She joins us in warning the public of the dangers of so-called ‘black henna’ temporary tattoos (BHTTs) after her son suffered a reaction earlier this year. Upon returning from a holiday in Morocco, Alfie aged six was left with a scar on his leg where the BHTT had been.

2 May 2017

Research shows how TET2 protein loss can open door for mutations that drive blood cancers

Imagine this scenario on a highway: A driver starts to make a sudden lane change but realizes his mistake and quickly veers back, too late. Other motorists have already reacted and, in some cases, collide. Meanwhile, the original motorist - the one who caused the problem - drives on.

25 Apr 2017

Second cancers are far deadlier in younger people than older adults

Second cancers in children and adolescents and young adults are far deadlier than they are in older adults and may partially account for the relatively poor outcomes of cancer patients ages 15-39 overall, a new study by UC Davis researchers has found.

20 Apr 2017

Noninvasive imaging test may spare benign kidney tumor patients from unnecessary surgery

The latest in a series of studies led by researchers at Johns Hopkins Medicine shows that addition of a widely available, noninvasive imaging test called 99mTc-sestamibi SPECT/CT to CT or MRI increases the accuracy of kidney tumor classification.

19 Apr 2017

Malignant News and Research

Researchers identify small RNA molecule that promotes deadly forms of breast cancer

Researchers discover novel mechanism that causes malignant pleural effusion in lung cancer patients

Researchers develop new imaging technique to ensure complete removal of tumor during surgery

NIBIB-funded scientists develop rapid and accurate tool for detecting early pancreatic cancer

Breast cancer cells undergo stiffening state prior to becoming malignant, study shows

Study prompts further assessment of tomato extracts’ use in gastric cancer prevention

Analyzing single-cell RNA data in pre-malignant tumors

Phase 1 trial shows safety and tolerability of oncolytic HSV-1 for children, young adults with cancer

Study shows link between susceptibility to malignant hyperthermia and exertional heat stroke

Vitamin A deficiency leads to loss of blood stem cells

Advanced endoscope to enable rapid, accurate diagnosis of early colon cancer

Heart failure patients have higher risk of death than people with common cancers

Study finds worse survival rates for heart failure despite advances in treatment

Lethal DNA re-replication may be used to attack cancer cells

Research sheds new light on surprising link between blood sugar and brain cancers

Researchers identify key player in initiation and progression of melanoma

Atomic Kitten Natasha Hamilton leads 'black henna' temporary tattoo warning

Research shows how TET2 protein loss can open door for mutations that drive blood cancers

Second cancers are far deadlier in younger people than older adults

Noninvasive imaging test may spare benign kidney tumor patients from unnecessary surgery

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