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7-day creatine ‘wash-in’ boosts muscle mass in women — but not long-term, study reveals

A 7-day creatine monohydrate wash-in increased lean body mass in females, especially in the trunk, but adding creatine to resistance training didn’t boost muscle gains beyond training alone. Higher doses or hydration tracking may be needed for long-term effects.

23 Mar 2025

Sticking to Life’s Essential 8 slashes cancer risk, major study shows

Long-term adherence to the American Heart Association’s “Life’s Essential 8” lifestyle score significantly reduces the risk of overall and site-specific cancers. Stable high LE8 scores over four years were linked to notably lower risks of lung, breast, liver, and colorectal cancers in a large Chinese cohort study.

23 Mar 2025

New monoclonal antibody shows promise in treating mucormycosis

Mucormycosis, a fungal infection caused by Mucorales, has high mortality rates in people with weakened immune systems and those suffering from severe trauma like burns, blast injuries or victims of natural disasters.

22 Mar 2025

Asgard archaea provide clues to the origin of complex life forms

Ten years ago, nobody knew that Asgard archaea even existed. In 2015, however, researchers examining deep-sea sediments discovered gene fragments that indicated a new and previously undiscovered form of microbes.

22 Mar 2025

Four breakthrough studies could revolutionize tuberculosis treatment

As of early 2025, tuberculosis cases are increasing in the U.S. This disease, often shortened to TB, causes significant lung damage and, if not treated, is almost always lethal.

22 Mar 2025

Groundbreaking study unveils key mechanism for neuronal identity regulation

A team of researchers from the Institute for Neurosciences, a joint center of the Spanish National Research Council (CSIC) and the Miguel Hernández University (UMH) of Elche, in collaboration with researchers from Columbia University (New York, USA), has identified a mechanism that regulates the production of two different proteins from the same gene.

22 Mar 2025

Targeting brain’s waste removal system may help combat cognitive decline

As aging bodies decline, the brain loses the ability to cleanse itself of waste, a scenario that scientists think could be contributing to neurodegenerative conditions such as Alzheimer's disease and Parkinson's disease, among others.

21 Mar 2025

New drug combination shows promise in treating melanoma brain metastasis

A federally funded research team led by Sheri Holmen, PhD, investigator at Huntsman Cancer Institute and professor in the Department of Surgery at the University of Utah (the U), is testing a new combination drug therapy that could both treat and prevent melanoma metastasis, or spreading from its original site, to the brain.

21 Mar 2025

Researchers uncover protective role of dopamine in regulating tau function

The research group led by Prof. Wang Chu from the College of Chemistry and Molecular Engineering at Peking University published a research article entitled "Quantitative Chemoproteomics Reveals Dopamine's Protective Modification of Tau" in Nature Chemical Biology (DOI:10.1038/s41589-025-01849-9).

21 Mar 2025

Scientists decode differentiation pathways of human blood stem cells

Every second, an adult generates around five million new blood cells to replace aging or dying ones, making the blood system a highly regenerative organ.

21 Mar 2025

Eye drops show potential to slow progression of human degenerative retinal diseases

Treatment shows potential to slow the progression of human degenerative eye diseases, including retinitis pigmentosa.

21 Mar 2025

Natural compounds identified as potential inhibitors of SARS-CoV-2 spike protein

The COVID-19 pandemic highlighted the urgent need for effective therapeutic agents against SARS-CoV-2.

20 Mar 2025

Exploring the therapeutic potential of flavonoids in type 2 diabetes

Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder with a rapidly increasing global prevalence. It is primarily characterized by insulin resistance, β-cell dysfunction, and impaired glucose homeostasis.

20 Mar 2025

A versatile toolbox sets gold standard for characterizing IRES activity in cells

Only recently has the ribosome - one of the oldest molecular machines in evolutionary terms - been recognized as an active regulator of gene expression at the level of protein biosynthesis.

20 Mar 2025

New function of Exportin-1 discovered in gene transcription

Researchers from Northwestern University have stumbled upon a previously unobserved function of a protein found in the cell nuclei of all flora and fauna.

20 Mar 2025

Deep sleep may protect against neurodegeneration

Sleep disturbances may accelerate neurodegeneration, but whether they cause or result from disease remains unclear. Improving sleep quality could help protect against cognitive decline and brain aging.

20 Mar 2025

Yale scientists develop advanced CRISPR tool to study complex genetic interactions

Advances in the gene-editing technology known as CRISPR-Cas9 over the past 15 years have yielded important new insights into the roles that specific genes play in many diseases.

20 Mar 2025

Breast cancer survivors face accelerated aging tied to tumors and treatment

Accelerated aging in breast cancer survivors is linked to treatments and tumor characteristics, with implications for long-term care and quality of life.

20 Mar 2025

Scientists discover irreversible peptide inhibitors for undruggable cancer target

For the first time scientists have identified promising drug candidates that bind irreversibly with a notoriously "undruggable" cancer protein target, permanently blocking it.

20 Mar 2025

Sapio Sciences makes AI-Native drug discovery seamless with NVIDIA BioNeMo

Sapio Sciences, the science-aware™ lab informatics platform, today announced the integration of the NVIDIA BioNeMo platform into the Sapio Lab Informatics Platform.

From Sapio Sciences 20 Mar 2025