Stem Cells News and Research

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Stem cells have the remarkable potential to develop into many different cell types in the body during early life and growth. In addition, in many tissues they serve as a sort of internal repair system, dividing essentially without limit to replenish other cells as long as the person or animal is still alive. When a stem cell divides, each new cell has the potential either to remain a stem cell or become another type of cell with a more specialized function, such as a muscle cell, a red blood cell, or a brain cell.

Study highlights the usefulness of organoids for basic research into coronaviruses

Researchers from the group of Hans Clevers in collaboration with the group of Bart Haagmans (Erasmus MC) established an organoid biobank to search for the genes that are essential for the spreading of a SARS-CoV2 infection.

20 Sep 2021

Study points to a possible new approach for treating MRSA superbug

A study released in STEM CELLS Translational Medicine, by researchers at the Baker Institute for Animal Health, part of Cornell University's College of Veterinary Medicine, Ithaca, N.Y., details in a relevant ex vivo model how treating wounds with the secretion of a type of stem cell called mesenchymal stromal cell (MSC) effectively reduced methicillin-resistant Staphylococcus aureus – better known as MRSA viability and stimulated the surrounding skin cells to build up a defense against the bacterial invader.

16 Sep 2021

Scientists investigate if the APOE4 gene in astrocytes relates to Alzheimer's disease

AD, the most frequent cause of dementia, affects an estimated 24 million people worldwide. With very limited treatment options, scientists are looking for ways to understand the disease better.

15 Sep 2021

Fountain of youth for the epigenome could become important in the treatment of osteoporosis

As we age, our bones become thinner, we suffer fractures more often, and bone-diseases such as osteoporosis are more likely to occur. One responsible mechanism involves the impaired function of the bone-marrow stem cells, which are required for the maintenance of bone integrity.

15 Sep 2021

A protein found to be effective at reversing aging in skeletal muscle cells

A University at Buffalo-led research team has shown that a protein named for the mythical land of youth in Irish folklore is effective at reversing aging in skeletal muscle cells.

15 Sep 2021

Researchers build the ovarian environment using mouse stem cells

Researchers led by Kyushu University have succeeded in using mouse stem cells to reconstruct structures in the ovarian environment critical for the generation of mature egg cells.

14 Sep 2021

Researchers focus on improving biomaterials used for bone and tissue repair

Bone injuries in the face and skull - known as craniomaxillofacial defects - can be caused by sports injuries, vehicle accidents, or battlefield injuries.

14 Sep 2021

A review of mesenchymal stem cell therapy for severe COVID-19

Researchers find that MSC treatment is highly tolerated and effective in reducing lung damage in COVID-19 patients and improving their chances of recovery.

13 Sep 2021

Scientists create a novel cell model for understanding human development

The earliest moments of human development—between the time of fertilization and when the embryo implants in the womb—have remained opaque to scientists.

9 Sep 2021

Optimized strategy for generating male germ-cells from mouse pluripotent stem cells

For species that rely on sexual reproduction, including mice and men, offspring can only happen if sperm from the male fertilize eggs from the female.

7 Sep 2021

Study offers important evidence for the safety of stem cell transplants

Stem cell transplants do not lead to changes in the DNA of the donor cells. That's according to a new study, which provides important evidence for the safety of this procedure.

7 Sep 2021

Researchers develop the smallest CRISPR to date for genome editing

A compact and efficient CRISPR-Cas system, named CasMINI, could be broadly useful for cell-engineering and gene-therapy applications because it is easier to deliver into cells. The findings appear in a study publishing September 3 in the journal Molecular Cell.

4 Sep 2021

Study establishes a new resource for exploring and understanding Alzheimer's disease

A study led by researchers from Brigham and Women's Hospital has established a new resource for exploring and understanding Alzheimer's disease (AD) on an individualized level.

2 Sep 2021

Cellular protein may be a potential new target for treating osteoporosis

A cellular protein whose normal function appears to suppress bone formation may be a potential new target for treating osteoporosis, suggests a collaborative study led by Weill Cornell Medicine and NewYork-Presbyterian investigators.

1 Sep 2021

Implanted cells deliver a biologic drug in response to inflammation in rheumatoid arthritis

With a goal of developing rheumatoid arthritis therapies with minimal side effects, researchers at Washington University School of Medicine in St. Louis have genetically engineered cells that, when implanted in mice, will deliver a biologic drug in response to inflammation.

1 Sep 2021

Green tea extract and cocoa-supplemented diets improve survival rate of aging mice

Aging-US published "Beneficial effects of dietary supplementation with green tea catechins and cocoa flavanols on aging-related regressive changes in the mouse neuromuscular system" which reported that green tea extract (GTE) and cocoa-supplemented diets significantly improved the survival rate of mice.

1 Sep 2021

New model shows how dysfunction in the air sacs initiates fibrotic cascade

Idiopathic pulmonary fibrosis (IPF) is the most common and severe form of lung disease characterized by relentless scarring leading to death within an average of four years from the time of diagnosis.

31 Aug 2021

Scientists identify small compounds that can regulate extracellular vesicle production

Biological vesicles are nano-sized containers that transport proteins and other substances within or between cells.

31 Aug 2021

Targeting and inhibiting a protein could provide more effective treatment for brain cancer

McGill University researchers identify proteins that drive cancer stem cells. Targeting and supressing a particular protein called galectin1 could provide a more effective treatment for glioblastoma, in combination with radiation therapy.

31 Aug 2021

Researchers develop adult lung organoids that represent all cell types

Since the COVID-19 pandemic reached the United States in early 2020, scientists have struggled to find laboratory models of SARS-CoV-2 infection, the respiratory virus that causes COVID-19. Animal models fell short; attempts to grow adult human lungs have historically failed because not all of the cell types survived.

31 Aug 2021

Stem Cells News and Research

Further Reading

Study highlights the usefulness of organoids for basic research into coronaviruses

Study points to a possible new approach for treating MRSA superbug

Scientists investigate if the APOE4 gene in astrocytes relates to Alzheimer's disease

Fountain of youth for the epigenome could become important in the treatment of osteoporosis

A protein found to be effective at reversing aging in skeletal muscle cells

Researchers build the ovarian environment using mouse stem cells

Researchers focus on improving biomaterials used for bone and tissue repair

A review of mesenchymal stem cell therapy for severe COVID-19

Scientists create a novel cell model for understanding human development

Optimized strategy for generating male germ-cells from mouse pluripotent stem cells

Study offers important evidence for the safety of stem cell transplants

Researchers develop the smallest CRISPR to date for genome editing

Study establishes a new resource for exploring and understanding Alzheimer's disease

Cellular protein may be a potential new target for treating osteoporosis

Implanted cells deliver a biologic drug in response to inflammation in rheumatoid arthritis

Green tea extract and cocoa-supplemented diets improve survival rate of aging mice

New model shows how dysfunction in the air sacs initiates fibrotic cascade

Scientists identify small compounds that can regulate extracellular vesicle production

Targeting and inhibiting a protein could provide more effective treatment for brain cancer

Researchers develop adult lung organoids that represent all cell types

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