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Scientists deliver nano-size packets of genetic code to treat brain tumors in mice

In a "proof of concept" study, scientists at Johns Hopkins Medicine say they have successfully delivered nano-size packets of genetic code called microRNAs to treat human brain tumors implanted in mice.

12 Jul 2018

Blood telomeres can help predict risk of disease worsening or death in COPD patients

Some patients with COPD demonstrate signs of accelerated aging. In a new study published in the journal CHEST researchers report that measuring blood telomeres, a marker of aging of cells, can be used to predict future risk of the disease worsening or death.

12 Jul 2018

Fighting cancer with engineered cancer cells

Researchers at Brigham and Women's Hospital have engineered cancer cells that track and kill cancer cells. The modified cancer cells have demonstrated anti-cancer efficacy in preclinical studies, destroying both primary and metastatic tumours.

12 Jul 2018

Study demonstrates new therapeutic targets for inflammation-associated colon cancer

Scientists headed by ICREA researcher Angel R. Nebreda at the Institute for Research in Biomedicine (IRB Barcelona) report a new mechanism that contributes to the development of inflammation-associated colon cancer and points to new therapeutic targets. The study has been published in the journal EMBO Molecular Medicine.

12 Jul 2018

Clinical trial examines impact of high-dose omega-3 and vitamin D on halting type 1 diabetes

Scientists from the Diabetes Research Institute at the University of Miami Miller School of Medicine today announced the launch of a new clinical trial that will assess the impact of high-dose omega-3 fatty acids and vitamin D supplementation on halting the progression of type 1 diabetes.

12 Jul 2018

New clinical trial to evaluate virotherapy and immunotherapy combination for ovarian, colorectal cancers

Ludwig Cancer Research and the Cancer Research Institute announce the initiation of a clinical trial to evaluate the combination of ONCOS-102, an experimental anti-tumor virotherapy, with the checkpoint blockade antibody IMFINZI (durvalumab) for advanced ovarian and colorectal cancers.

12 Jul 2018

Study: Hepatitis C vaccine could drastically reduce transmission among injecting drug users

Among the most serious consequences of the opioid epidemic is the spread of hepatitis C among injecting drug users.

12 Jul 2018

Scientists pinpoint new therapeutic targets for inflammation-associated colon cancer

Scientists headed by ICREA researcher Angel R. Nebreda at the Institute for Research in Biomedicine report a new mechanism that contributes to the development of inflammation-associated colon cancer and points to new therapeutic targets

11 Jul 2018

Study uncovers process that neutralizes tumor cells

Researchers from the University of California San Diego have identified an unexpected mechanism that could help determine whether a cancer patient will respond to immunotherapy.

11 Jul 2018

Researchers highlight the need for wider access to HIV prevention drugs

Despite highly effective anti-HIV pharmaceuticals having been used worldwide for almost a decade, HIV has not been conquered.

11 Jul 2018

Researchers assess role of physician in preventing intimate partner violence perpetration

Intimate partner violence is prevalent and has lasting impacts on the health and well-being of the entire family involved.

11 Jul 2018

Mature kidney podocytes for developing cell therapies and drug discovery

Human stem cells are of great interest in the fields of regenerative medicine and medical research because they reproduce indefinitely and can differentiate into every other cell type found in the body.

11 Jul 2018

Aspirin desensitization can help alleviate alcohol-induced allergies in patients with AERD

Patients who suffer from Aspirin Exacerbated Respiratory Disease often experience an additional allergic reaction when drinking alcohol, including nasal congestion, wheezing, and a runny nose.

10 Jul 2018

Researchers use genome editing to reduce cholesterol levels in animal model

Using genome editing to inactivate a protein called PCSK9 effectively reduces cholesterol levels in rhesus macaques, a species of monkey, according to researchers from the Perelman School of Medicine at the University of Pennsylvania.

10 Jul 2018

Newly discovered nanobody holds promise to advance targeted therapies for several diseases

Researchers from Case Western Reserve University School of Medicine have found a nanobody that holds promise to advance targeted therapies for a number of neurological diseases and cancer.

10 Jul 2018

Researchers develop first comprehensive atlas of lung tumor cells

Researchers from VIB, Leuven University and University Hospital Leuven studied thousands of healthy and cancerous lung cells to create the first comprehensive atlas of lung tumor cells.

10 Jul 2018

Altitude sickness drug may offer significant gains for patients with glioblastoma

A drug used to treat altitude sickness -- as well as glaucoma, epilepsy, heart failure and seizures -- may also offer significant gains for patients with a fast-growing brain tumor known as glioblastoma, according to a study published July 4, 2018, in the journal Science Translational Medicine.

10 Jul 2018

'The Pediatric Asthma Yardstick' offers guidance to treat children of all ages

Although about 10 percent of school-aged children in the United States have asthma, there are few comprehensive U.S. guidelines for treating pediatric asthma.

10 Jul 2018

Researchers use x-ray crystallography to reveal how curcumin inhibits cancer

Through x-ray crystallography and kinase-inhibitor specificity profiling, University of California San Diego School of Medicine researchers, in collaboration with researchers at Peking University and Zhejiang University, reveal that curcumin, a natural occurring chemical compound found in the spice turmeric, binds to the kinase enzyme dual-specificity tyrosine-regulated kinase 2 at the atomic level.

10 Jul 2018

Human trial identifies common blood pressure medication as safe, effective therapy for diabetes

Researchers at the University of Alabama at Birmingham Comprehensive Diabetes Center have discovered a safe and effective novel therapy to reduce insulin requirements and hypoglycemic episodes in adult subjects with recent onset Type 1 diabetes by promoting the patient's own beta cell function and insulin production -- the first such discovery to target diabetes in this manner.

9 Jul 2018

Therapy News and Research

Scientists deliver nano-size packets of genetic code to treat brain tumors in mice

Blood telomeres can help predict risk of disease worsening or death in COPD patients

Fighting cancer with engineered cancer cells

Study demonstrates new therapeutic targets for inflammation-associated colon cancer

Clinical trial examines impact of high-dose omega-3 and vitamin D on halting type 1 diabetes

New clinical trial to evaluate virotherapy and immunotherapy combination for ovarian, colorectal cancers

Study: Hepatitis C vaccine could drastically reduce transmission among injecting drug users

Scientists pinpoint new therapeutic targets for inflammation-associated colon cancer

Study uncovers process that neutralizes tumor cells

Researchers highlight the need for wider access to HIV prevention drugs

Researchers assess role of physician in preventing intimate partner violence perpetration

Mature kidney podocytes for developing cell therapies and drug discovery

Aspirin desensitization can help alleviate alcohol-induced allergies in patients with AERD

Researchers use genome editing to reduce cholesterol levels in animal model

Newly discovered nanobody holds promise to advance targeted therapies for several diseases

Researchers develop first comprehensive atlas of lung tumor cells

Altitude sickness drug may offer significant gains for patients with glioblastoma

'The Pediatric Asthma Yardstick' offers guidance to treat children of all ages

Researchers use x-ray crystallography to reveal how curcumin inhibits cancer

Human trial identifies common blood pressure medication as safe, effective therapy for diabetes

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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