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Study does not find causal association between assisted reproduction and ovarian cancer risk

Following concerns over many years that hormonal stimulation of the ovaries necessary for IVF may increase the risk of ovarian cancer, a nationwide cohort study from Denmark has now concluded that any perceived increase in risk is actually a statistical bias resulting from vigilant diagnosis at the time of treatment.

3 Jul 2018

Mayo researchers determine how DNA repair protein gets to the site of damage

Damage to DNA is a daily occurrence but one that human cells have evolved to manage. Now, in a new paper published in Nature Structural & Molecular Biology, Mayo researchers have determined how one DNA repair protein gets to the site of DNA damage. The authors say they hope this discovery research will help identify new therapies for ovarian cancer.

3 Jul 2018

New method separates circulating tumor cells from blood samples using sound waves

Using sound waves, an international team of researchers has developed a gentle, contact-free method for separating circulating tumor cells from blood samples that is fast and efficient enough for clinical use.

3 Jul 2018

Anticonvulsants found to be ineffective for low back pain and can have adverse effects

Anticonvulsant drugs are increasingly being used to treat low back pain, but a new study in CMAJ finds they are ineffective and can have adverse effects.

3 Jul 2018

Finnish researchers gain new insights on brain activity during general anesthesia

Finnish researchers have gained new information on brain activity during general anesthesia by recording changes in the electrical activity of the brain.

3 Jul 2018

Researchers develop new methods for studying evolution of cancer treatment resistance

New methods of studying the evolution of treatment resistance in head and neck cancer are being developed by researchers at the Johns Hopkins Kimmel Cancer Center.

3 Jul 2018

Increase in marker of inflammation from mid to late life linked with dementia

Researchers at Johns Hopkins have added to evidence that rising and chronic inflammation as measured by a biomarker in the blood in middle and late age are linked to visible structural changes in the brains of people with poor cognition and dementia.

2 Jul 2018

Low-dose aspirin may reduce amyloid plaques in the brain, study shows

A regimen of low-dose aspirin potentially may reduce plaques in the brain, which will reduce Alzheimer's disease pathology and protect memory, according to neurological researchers at Rush University Medical Center, who published the results of their study today in the July issue of The Journal of Neuroscience.

2 Jul 2018

Compounds found in green tea and red wine offer hope to treat inborn congenital metabolic diseases

A new Tel Aviv University study suggests there is hope of treating certain inborn congenital metabolic diseases -- a hope found in green tea and in red wine.

2 Jul 2018

New blood test can help determine the state of a person's internal clock

With a new blood test, researchers at the Charité - Universitätsmedizin Berlin can determine the state of the internal clock of a person. Once the internal rhythm of patient is known, drugs could be administered at particular times of day making them more effective and with fewer side effects than standard therapy.

2 Jul 2018

Cancerous cells in aggressive childhood brain tumor work together to infiltrate the brain, shows study

Scientists have discovered that cancerous cells in an aggressive type of childhood brain tumor work together to infiltrate the brain, and this finding could ultimately lead to much needed new treatments, according to a new study published in Nature Medicine today (Monday).

2 Jul 2018

U.S. researchers recommend development of anti-cancer drugs based on mechanism of Namodenoson

Can-Fite BioPharma Ltd., a biotechnology company advancing a pipeline of proprietary small molecule drugs that address cancer, liver and inflammatory diseases, today announced that U.S. researchers published scientific findings recommending development of anti-Liver Cancer Drugs based on a mechanism of action utilized by Namodenoson.

2 Jul 2018

Cilia appears to play key role in formation of melanoma

Most cells in the human body have a cilium, a slender cell protuberance that picks up signals from the cell's external environment.

2 Jul 2018

Simple DNA test can predict risk of bad side effects to thiopurine drugs

Screening a tiny section of DNA could help East Asian patients avoid severe reactions to some medications.

2 Jul 2018

Streamlining and translating basic science discoveries into the clinic

To make sure that good ideas to enhance healthcare are not lost due to a lack of resources, a growing number of centers at Penn Medicine organize forums to pitch ideas to improve medical devices and technology, hold annual competitions to fund studies to improve patient care while keeping costs down, and sponsor seed grants for programs focused on patients who need individualized tailoring of their treatment.

2 Jul 2018

New hydrogel takes stretchability, self-healing, strain sensitivity to new limits

A metal carbide within a hydrogel composite senses, stretches and heals like human skin for use in medicine and robotics.

2 Jul 2018

Psychedelics and their role in treatment of mental health disorders

Psychedelics such as LSD, magic mushrooms, mescaline etc. have garnered renewed interest in the scientific world because of the possible role they could play in mental health problems. Ketamine remains the only hallucinogen at present that is used clinically as an anesthetic agent. The others are all classified under banned drugs.

2 Jul 2018

Study using i2b2 could help standardize artificial coma treatment for RSE patients

Status epilepticus, a dangerous condition in which epileptic seizures follow one another for a duration of five or more minutes without the victim's regaining consciousness between them, is the second most common neurological emergency in the United States, with a recorded maximum of around 150,000-plus cases per year.

30 Jun 2018

Study finds that several existing anti-cancer drugs may work in part by binding to RNA

Bolstering the notion that RNA should be considered an important drug-discovery target, scientists at Scripps Research have found that several existing, FDA-approved anti-cancer drugs may work, in part, by binding tightly to RNA, the regulators of the basic activities of life within cells.

30 Jun 2018

KU Cancer Center launches clinical trial to eliminate radiation therapy for HER2-positive breast cancer

Researchers at The University of Kansas Cancer Center have launched a clinical trial that eliminates radiation from the treatment protocol for an invasive type of breast cancer that accounts for one-fifth of all breast cancer patients.

30 Jun 2018

Drugs News and Research

Study does not find causal association between assisted reproduction and ovarian cancer risk

Mayo researchers determine how DNA repair protein gets to the site of damage

New method separates circulating tumor cells from blood samples using sound waves

Anticonvulsants found to be ineffective for low back pain and can have adverse effects

Finnish researchers gain new insights on brain activity during general anesthesia

Researchers develop new methods for studying evolution of cancer treatment resistance

Increase in marker of inflammation from mid to late life linked with dementia

Low-dose aspirin may reduce amyloid plaques in the brain, study shows

Compounds found in green tea and red wine offer hope to treat inborn congenital metabolic diseases

New blood test can help determine the state of a person's internal clock

Cancerous cells in aggressive childhood brain tumor work together to infiltrate the brain, shows study

U.S. researchers recommend development of anti-cancer drugs based on mechanism of Namodenoson

Cilia appears to play key role in formation of melanoma

Simple DNA test can predict risk of bad side effects to thiopurine drugs

Streamlining and translating basic science discoveries into the clinic

New hydrogel takes stretchability, self-healing, strain sensitivity to new limits

Psychedelics and their role in treatment of mental health disorders

Study using i2b2 could help standardize artificial coma treatment for RSE patients

Study finds that several existing anti-cancer drugs may work in part by binding to RNA

KU Cancer Center launches clinical trial to eliminate radiation therapy for HER2-positive breast cancer

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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