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Discovery of protein that may be key to treating tropical diseases

Neglected tropical diseases form a group of infectious parasitic diseases that affect a large percentage of the world population, mostly in emerging nations. Sleeping sickness affects millions in sub-Saharan Africa and is caused by the protozoan parasite, Trypanosoma brucei, which is transmitted by the tsetse fly.

27 Aug 2019

Polycystic kidney disease may be preventable

Kidney failure is a lifelong burden in hundreds of thousands of people who need to be treated either by dialysis or a kidney transplant. Both procedures significantly increase the cost of healthcare and reduce the quality of life.

26 Aug 2019

Early detection method for pinpointing molecular signatures of Lyme disease

When researchers examined the mitochondrial DNA of Ötzi, a man entombed in ice high in the Tyrolean Alps some 5,300 years ago, they made a startling discovery.

26 Aug 2019

Researchers discover how fatty liver disease develops in lean people

Researchers from The Westmead Institute for Medical Research (WIMR) have discovered how fatty liver disease develops in lean people, aiding the development of potential treatments for these patients.

26 Aug 2019

"Australian" genetic mutation provides clues to Alzheimer’s mechanism

In an astonishing new breakthrough in Alzheimer’s research, the molecular basis of early-onset Alzheimer’s disease (AD) and age-linked AD has been identified by looking at one type of genetic mutation.

26 Aug 2019

Blood sugar levels linked to DNA damage and cancer in diabetics

Increased blood sugar levels in diabetics could damage DNA and make the genome unstable, increasing the risk of certain cancers.

26 Aug 2019

Salk researchers develop new gene-editing tool to target broad range of mutations, cell types

The ability to edit genes in living organisms offers the opportunity to treat a plethora of inherited diseases. However, many types of gene-editing tools are unable to target critical areas of DNA, and creating such a technology has been difficult as living tissue contains diverse types of cells.

26 Aug 2019

Removing tumor's protective wall could help boost the effects of cancer treatments

Scientists may have found a way to pull down the protective wall that surrounds tumors, potentially re-exposing them to the killing power of the immune system and immunotherapy treatments, according to a study part funded by Cancer Research UK and published in EBioMedicine today (Monday).

26 Aug 2019

Researchers target cancer's protective barrier

Cancer cells are notorious for their camouflage work, which enables them to escape immune targeting. Now scientists are learning how to strip away the disguise and allow the immune system to do its work, by targeting cells called myeloid-derived suppressor cells (MDSCs) that shield the tumor. This would also enhance the effectiveness of newer cancer immunotherapies like Chimeric-Antigen Receptor T cell (CAR-T).

26 Aug 2019

Scientists identify how nature builds with chitin

Writers know the power of the pen, but scientists are just discovering its secrets.

25 Aug 2019

Fruit fly develops a long-lasting body-size memory, shows research

In order to orient themselves and survive in their environment, animals must develop a concept of their own body size.

25 Aug 2019

New mechanisms to enable regeneration of injured nerve fibers

Injuries to nerve fibers in the brain, spinal cord, and optic nerves usually result in functional losses as the nerve fibers are unable to regenerate.

23 Aug 2019

Animal-assisted interventions help reduce patient stress in aeromedical staging facilities

They're physically and emotionally wounded – most likely suffering from post-traumatic stress. Members of the United States military who serve abroad often return to the U.S. to treat their injuries and must be transported by aeromedical evacuation between medical facilities.

23 Aug 2019

Researchers decode chain of molecules critical for growth and survival of pancreatic cancer

Researchers at Georgetown Lombardi Comprehensive Cancer Center have decoded a chain of molecules that are critical for the growth and survival of pancreatic ductal adenocarcinoma (PDAC) - the most common and also the most lethal form of pancreatic cancer.

23 Aug 2019

Head-to-head comparison of three breast cancer drugs reveals important differences

Every year, more than 250,000 women in the U.S. are diagnosed with breast cancer. When detected early, patients with the most common form--which tests positive for hormone receptors (HR+) and negative for the HER2 receptor--usually respond well to treatment.

23 Aug 2019

Scientists identify unique way to treat incurable type of children's brain cancer

An international team of researchers led by Yale University, University of Iowa, and the Translational Genomics Research Institute, an affiliate of City of Hope, has discovered a new pathway that may improve success against an incurable type of children's brain cancer.

23 Aug 2019