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Merck announces FDA acceptance of supplemental Biologics License Application for KEYTRUDA

Merck, known as MSD outside the United States and Canada, today announced that the U.S. Food and Drug Administration has accepted for standard review a new supplemental Biologics License Application for KEYTRUDA, Merck's anti-PD-1 therapy, as adjuvant therapy in the treatment of patients with resected, high-risk stage III melanoma and granted a Prescription Drug User Fee Act, or target action, date of February 16, 2019.

25 Jun 2018

AntiCancer's oral drug overcomes gemcitabine resistance in mouse models of human pancreatic cancer

Pancreatic cancer is lethal in about 95% of cases mostly due to failure of first-line therapy gemcitabine. AntiCancer Inc.'s oral methioninase (AC 00619), which is in late pre-clinical development as an anti-cancer as well as an anti-aging drug, has now been shown to overcome gemcitabine resistance in mouse models of human pancreatic cancer, including AntiCancer's patient-derived orthotopic xenograft mouse models.

25 Jun 2018

Study: Men tolerate stress urinary incontinence for years before seeking medical help

Men often tolerate stress urinary incontinence for more than two years before seeking medical help - and one-third put up with it for more than five years, making it important for doctors to check for this problem, a new study from UT Southwestern researchers advises.

25 Jun 2018

Novel model to address post-disaster behavioral health issues may also help other communities

Faculty in LSU Health New Orleans schools of Medicine and Public Health and colleagues report that a collaborative effort to build capacity to address behavioral health and promote community resilience after the 2016 Great Flood in Baton Rouge, LA successfully expanded local behavioral health services delivery capacity and that the model may be useful to other disaster-struck communities.

25 Jun 2018

Fearing deportation, immigrant parents are opting out of health benefits for kids

The fear of family separation is nothing new for many immigrants already living in the U.S. In fact, that fear, heightened in recent weeks, has been forcing a tough decision for a while. Advocates say a growing number of American children are dropping out of Medicaid and other government programs because their parents are not citizens.

25 Jun 2018

ABPI associated with NHS for 70 years in pharmaceutical research

In this special year, both the NHS and the Association of the British Pharmaceutical Industry are celebrating our respective 70th anniversaries. The histories of these two organizations have been inextricably linked since 1948 and our relationship with the NHS continues to go from strength to strength.

25 Jun 2018

Studying The Effects of Microgravity on Muscle Mass

Studying the effects of gravity on muscle cells can give us an insight into muscle wastage diseases, and potentially guide the development of new therapies. Professor Louis Yuge discusses his research and the cellular changes that occur in response to microgravity.

25 Jun 2018

Unique patch could revolutionize treatment of painful recurring ulcers

A plaster which sticks to the inside of your mouth is revolutionising the treatment of painful recurring ulcers.

25 Jun 2018

Study highlights inadequate effort of health care insurers to combat opioid epidemic

Health care insurers including Medicare, Medicaid and major private insurers have not done enough to combat the opioid epidemic, suggests a study led by researchers at Johns Hopkins Bloomberg School of Public Health.

22 Jun 2018

DNA patterns in circulating blood cells can help identify spastic cerebral palsy

A Delaware team including Erin Crowgey, PhD, associate director of Bioinformatics with Nemours Biomedical Research, has published a study in the peer-reviewed journal BMC Bioinformatics, showing that DNA patterns in circulating blood cells can be used to help identify spastic cerebral palsy (CP) patients.

22 Jun 2018

AAA doses first patients in two clinical studies with PSMA-R2 for prostate cancer

Advanced Accelerator Applications S.A., a Novartis company and leader in nuclear medicine theragnostics, today announced that the first patients have been dosed in two Phase I/II clinical studies of radiolabeled PSMA-R2, a urea-based ligand of Prostate-Specific Membrane Antigen, which is commonly expressed on prostate cancer cells.

22 Jun 2018

Study suggests proteinuria lowering as important target in managing pediatric CKD

In a study of children with chronic kidney disease, blood pressure medications reduced protein excretion in the urine, which was linked with a lower risk of disease progression.

22 Jun 2018

Researchers discover drug compound that inhibits movement of cancer cells

Fighting cancer means killing cancer cells. However, oncologists know that it's also important to halt the movement of cancer cells before they spread throughout the body.

22 Jun 2018

UC San Diego launches new bacteriophage therapy center

With microbial resistance to antibiotics growing into a major global health crisis, researchers at University of California San Diego School of Medicine, in collaboration with national research institutions and private industry, are leveraging hard-won expertise to exploit a natural viral enemy of pathogenic bacteria, creating North America's first Center for Innovative Phage Applications and Therapeutics

22 Jun 2018

Unusual cell-to-cell communication in glioblastoma promotes aggressiveness and therapy resistance

A surprising form of cell-to-cell communication in glioblastoma promotes global changes in recipient cells, including aggressiveness, motility, and resistance to radiation or chemotherapy.

22 Jun 2018

Researchers diagnose cerebral palsy using AI and next-generation sequencing

Researchers have shown that patients with spastic cerebral palsy (CP) can be identified using DNA methylation patterns in circulating blood cells.

22 Jun 2018

CellGenix completes first phase of facility expansion to meet rising demands for GMP cell culture reagents

CellGenix, a global manufacturing leader of GMP-grade raw materials for cell therapy, gene therapy and tissue-engineered products, successfully completed the first phase of its headquarters’ expansion as more customers approach late-stage clinical development and commercialization.

22 Jun 2018

Therapy News and Research

Merck announces FDA acceptance of supplemental Biologics License Application for KEYTRUDA

AntiCancer's oral drug overcomes gemcitabine resistance in mouse models of human pancreatic cancer

Study: Men tolerate stress urinary incontinence for years before seeking medical help

Novel model to address post-disaster behavioral health issues may also help other communities

Fearing deportation, immigrant parents are opting out of health benefits for kids

ABPI associated with NHS for 70 years in pharmaceutical research

Studying The Effects of Microgravity on Muscle Mass

Unique patch could revolutionize treatment of painful recurring ulcers

Study highlights inadequate effort of health care insurers to combat opioid epidemic

DNA patterns in circulating blood cells can help identify spastic cerebral palsy

AAA doses first patients in two clinical studies with PSMA-R2 for prostate cancer

Study suggests proteinuria lowering as important target in managing pediatric CKD

Researchers discover drug compound that inhibits movement of cancer cells

UC San Diego launches new bacteriophage therapy center

Unusual cell-to-cell communication in glioblastoma promotes aggressiveness and therapy resistance

Researchers diagnose cerebral palsy using AI and next-generation sequencing

CellGenix completes first phase of facility expansion to meet rising demands for GMP cell culture reagents

Osteopathic manual therapy affecting the diaphragm improves chronic low back pain

Researchers outline a connection between subplate neurons and brain disorders

Researchers discover new type of cell that hinders formation of fat cells

Industry Focus eBook - Life Science Microscopy (2nd Edition) eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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