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Study may explain how chemoresistance evolves over time in some triple-negative breast cancers

Triple-negative breast cancer is an aggressive form of the disease accounting for 12 to 18 percent of breast cancers. It is a scary diagnosis, and even though chemotherapy can be effective as standard-of-care, many patients become resistant to treatment.

20 Apr 2018

Low-cost blood test for multiple myeloma can deliver same diagnostic information as bone biopsy

The diagnosis and treatment of multiple myeloma, a cancer affecting plasma cells, traditionally forces patients to suffer through a painful bone biopsy. During that procedure, doctors insert a bone-biopsy needle through an incision to get a bone marrow sample - or make a larger incision and remove a section of bone via surgery.

20 Apr 2018

Scientists use CRISPR tool to make multiple edits to DNA samples 'in vitro'

Scientists at Christiana Care Health System's Gene Editing Institute have developed a potentially breakthrough CRISPR gene-editing tool. It could allow researchers to take fragments of DNA extracted from human cells, put them into a test tube, and quickly and precisely engineer multiple changes to the genetic code, according to a new study published today in the CRISPR Journal.

20 Apr 2018

Meditation could help reduce anxiety levels and some heart health risk factors

It sounds like a late-night commercial: In just one hour you can reduce your anxiety levels and some heart health risk factors. But a recent study with 14 participants shows preliminary data that even a single session of meditation can have cardiovascular and psychological benefits for adults with mild to moderate anxiety.

20 Apr 2018

Evolutionary history of tumor helps predict severity of prostate cancer

Findings from Canadian Prostate Cancer Genome Network (CPC-GENE) researchers and their collaborators, published today in Cell, show that the aggressiveness of an individual prostate cancer can be accurately assessed by looking at how that tumor has evolved. This information can be used to determine what type and how much treatment should be given to each patient, or if any is needed at all.

20 Apr 2018

Experimental compound reduces destructive inflammation to improve stroke outcome

An experimental compound appears to improve stroke outcome by reducing the destructive inflammation that can continue months after a stroke, scientists report.

20 Apr 2018

Novel gold nanoparticle technology could guide cancer treatment in real-time

A new blood test using gold nanoparticles could soon give oncologists an early and more accurate prognosis of how cancer treatment is progressing and help guide the on-going therapy of patients.

20 Apr 2018

New integrated POC tool detects biomarkers of heart failure rapidly and precisely

More than 26 million patients worldwide suffer from heart failure every year, according to the European Heart Failure Association. A disorder often associated with a bad diagnosis, with the consequent increase in mortality and morbidity, and frequent re-hospitalizations, which are a great problem for patients and their families, as well as a great economic burden for the healthcare system.

From Micronit Microtechnologies B.V. 20 Apr 2018

AYOXXA to develop multiplex immunoassay to support treatment of sepsis patients

AYOXXA Biosystems GmbH, an international biotechnology company, will develop a multiplex assay to support the treatment of sepsis patients as part of the project "SepsisData.Net.NRW - Digitized Pattern Recognition for Personalized Treatment of Sepsis Patients". The development will be based on the Company’s innovative bead-based protein analysis platform LUNARIS™.

20 Apr 2018

New non-invasive nerve stimulation may offer relief for people with hand tremor

People with tremors in their hands from a condition called essential tremor may find some relief from a new, non-invasive type of nerve stimulation, according to a preliminary scientific abstract released today that will be presented at the American Academy of Neurology's 70th Annual Meeting in Los Angeles, April 21 to 27, 2018.

20 Apr 2018

Triple-negative breast cancer found to be chemoresistant prior to treatment

Difficult to treat and aggressive "triple-negative" breast cancer is chemoresistant even before chemotherapy begins, a new study by researchers from Karolinska Institutet and the University of Texas MD Anderson Cancer Center reports. The findings, which are published in the journal Cell, may lead to better and more personalized treatments for breast cancer.

19 Apr 2018

Innovative device shows promise in capturing and releasing circulating tumor cells

For years, bioengineer Yaling Liu has been in pursuit of the deadly tumor cell. Liu has been perfecting a microfluidic device the size of two quarters that has the ability to catch and release circulating tumor cells (CTCs)--cancer cells that circulate in a cancer patient's blood.

19 Apr 2018

Genetic make-up impacts long-term effectiveness of phobia treatment

Researchers have discovered that variations in the efficacy of psychological treatment for phobias are associated with the serotonin transporter gene.

19 Apr 2018

Researcher presents case study of asymptomatic patient with severe mitral regurgitation

In primary mitral regurgitation there are anatomic abnormalities of the mitral valve causing backward flow, placing a hemodynamic burden on the left ventricle.

19 Apr 2018

Researchers use optogenetics to treat chronic pain

The finger prick from a thorn generates an immediate sensory response. In that instant, neurons at the injury site fire an electrical signal along a nerve fiber to the central nervous system. Our brain notes to avoid further encounters with thorns and the painful insult subsides.

18 Apr 2018

Novel stem cell therapy may transform current paradigms for treating heart failure patients

Clinical trial planning is underway at MedStar Heart & Vascular Institute to determine whether a novel stem cell therapy will improve heart function for patients with heart failure.

18 Apr 2018

Nanodisc-delivered cancer treatment helps eliminate tumors

In the wrestling match with cancer, chemoimmunotherapy is the new strong arm, and it is building muscle with a nanodisc disguised as "good cholesterol."

18 Apr 2018

Experts propose new solutions to increase benefit, affordability of targeted cancer medicines

Spending on cancer drugs in the United States has nearly doubled in the past five years and continues to grow, imposing substantial financial burden on patients with cancer.

18 Apr 2018

High-resolution images of tumor vasculature using new technology

Thanks to a new method of analyzing ultrasound images, conventional scanners can be used for generating high-res images of blood vessels in tumors. This approach makes it easier to distinguish between different types of tumors, and it facilitates the tracking of the progress and success of chemotherapy.

18 Apr 2018

Wide-scale distribution of naloxone effectively prevents overdose deaths, study finds

A new study in The Lancet Public Health shows the rapid expansion of British Columbia's Take Home Naloxone program significantly reduced the number of fentanyl-related overdose deaths in 2016.

18 Apr 2018

Therapy News and Research

Study may explain how chemoresistance evolves over time in some triple-negative breast cancers

Low-cost blood test for multiple myeloma can deliver same diagnostic information as bone biopsy

Scientists use CRISPR tool to make multiple edits to DNA samples 'in vitro'

Meditation could help reduce anxiety levels and some heart health risk factors

Evolutionary history of tumor helps predict severity of prostate cancer

Experimental compound reduces destructive inflammation to improve stroke outcome

Novel gold nanoparticle technology could guide cancer treatment in real-time

New integrated POC tool detects biomarkers of heart failure rapidly and precisely

AYOXXA to develop multiplex immunoassay to support treatment of sepsis patients

New non-invasive nerve stimulation may offer relief for people with hand tremor

Triple-negative breast cancer found to be chemoresistant prior to treatment

Innovative device shows promise in capturing and releasing circulating tumor cells

Genetic make-up impacts long-term effectiveness of phobia treatment

Researcher presents case study of asymptomatic patient with severe mitral regurgitation

Researchers use optogenetics to treat chronic pain

Novel stem cell therapy may transform current paradigms for treating heart failure patients

Nanodisc-delivered cancer treatment helps eliminate tumors

Experts propose new solutions to increase benefit, affordability of targeted cancer medicines

High-resolution images of tumor vasculature using new technology

Wide-scale distribution of naloxone effectively prevents overdose deaths, study finds

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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