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Estrogen could be viable treatment option for Parkinson's patients

Brain-selective estrogen treatment improves the symptoms of Parkinson’s disease in male mice, according to new research published in JNeurosci. These findings may help explain the sex differences in Parkinson’s disease and could lead to estrogen-based treatments.

From Society for Neuroscience 13 Aug 2019

Study highlights how high fat diet affects one component of gut immune system

Researchers have discovered how our choice of diet can weaken our gut immune system and lead to the development of diabetes.

13 Aug 2019

New research suggests another possible mechanism for Alzheimer’s

Neurofibrillary plaques and tau protein are among the most widely known pathological entities characterizing Alzheimer’s disease (AD), but new research at the University of California, Riverside, has come up with another plausible explanation for this debilitating disorder.

13 Aug 2019

Tissue model of Alzheimer's mimics beta-amyloid's effects on blood-brain barrier

Beta-amyloid plaques, the protein aggregates that form in the brains of Alzheimer's patients, disrupt many brain functions and can kill neurons. They can also damage the blood-brain barrier — the normally tight border that prevents harmful molecules in the bloodstream from entering the brain.

13 Aug 2019

Breakthrough study identifies specific antibody target implicated in neuropsychiatric lupus

A breakthrough study by a SUNY Downstate Health Sciences University research team has identified a specific antibody target implicated in neuropsychiatric symptoms of lupus.

13 Aug 2019

Researchers identify alternate chemistry that could account for Alzheimer's pathologies

Alzheimer's disease, the most common cause of dementia among the elderly, is characterized by plaques and tangles in the brain, with most efforts at finding a cure focused on these abnormal structures.

13 Aug 2019

Engineers develop tissue model that mimics beta-amyloid's effects on blood-brain barrier

Beta-amyloid plaques, the protein aggregates that form in the brains of Alzheimer's patients, disrupt many brain functions and can kill neurons.

13 Aug 2019

Alzheimer's disease attacks brain regions responsible for wakefulness

Researchers and caregivers have noted that excessive daytime napping can develop long before the memory problems associated with Alzheimer's disease begin to unfold.

13 Aug 2019

Scientists identify hereditary pancreatic cancer risk mutation

Scientists studying a highly cancer-prone family have identified a rare, inherited gene mutation that dramatically raises the lifetime risk of pancreatic and other cancers.

12 Aug 2019

Psychiatric symptoms may indicate the beginning of Alzheimer’s disease

Researchers at UC San Francisco (UCSF) and the University of São Paulo have shown that the earliest stages of Alzheimer’s brain pathology are tightly linked to neuropsychiatric symptoms such as anxiety, depression and sleep disturbances.

12 Aug 2019

Excessive daytime sleeping could be an early sign of Alzheimer’s

Excessive daytime napping often develops long before the memory problems associated with Alzheimer's disease occur. Now, researchers may have found the striking new biological explanation for this phenomenon.

12 Aug 2019

New T cell detection method promises personalized immunotherapy for melanomas

An important new study shows that better T cell detection is now possible using revolutionary technology. T cells are a type of lymphocyte, which in turn belongs to the diverse family of immune cells. They take part in cancer fighting as well as in most other immune responses.

12 Aug 2019

Diet with reduced carbohydrate content may be beneficial to patients with type 2 diabetes

Patients with type 2 diabetes improve their ability to regulate blood sugar levels if they eat food with a reduced carbohydrate content and an increased share of protein and fat.

12 Aug 2019

Study examines the role of enzymes in stress regulation mechanisms

Scientists of South Ural State University are studying enzymes that can break down stress hormones. They are also finding a way to regulate the activity of these enzymes. It will help to cure diseases caused by stress.

12 Aug 2019

UAMS Myeloma Center receives $542,486 grant from Leukemia & Lymphoma Society

Brian Walker, Ph.D., with the Myeloma Center at the University of Arkansas for Medical Sciences has received a $542,486, three-year grant from the Leukemia & Lymphoma Society to look at changes in the DNA sequence that effects the development and advancement of multiple myeloma, a cancer of plasma cells in the blood.

12 Aug 2019

Biologists discover the intricacies of 'on/off switch' that creates cell differentiation

A team of biologists has discovered how cells become different from each other during embryogenesis, a finding that offers new insights into genetic activity and has implications for better understanding the onset of disease and birth defects.

12 Aug 2019

Research shows that water molecules do not co-migrate via potassium channel

Do only potassium ions pass through the selectivity filter of a potassium channel, or are there water molecules between the ions? This question has been a source of controversy for years.

12 Aug 2019

Innovative technology could help treat cancer more selectively and effectively

Treating cancer more selectively and more effectively - this could be achieved with an innovative technology developed by teams of researchers at the Leibniz-Forschungsinstitut für Molekulare Pharmakologie and the Ludwig-Maximilians-Universität München.

9 Aug 2019

Researchers identify direct toxic action of beta-amyloid in the brain

The brains of Alzheimer's patients who have already developed clinical symptoms contain large clumps of the protein beta-amyloid, known as plaques. Many therapeutic approaches focus on removing plaques, but such attempts have met with only limited success to date.

9 Aug 2019

Research offers new clues into why cognitive functions become impaired with age

Research at the University of Leicester is offering new clues into how and why cognitive functions such as memory and learning become impaired with age. A paper published recently in a specialist neuroscience journal shows that a crucial factor is calcium levels in specific cells in the brain.

9 Aug 2019