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Nerve injuries found to affect the entire immune system in unexpected ways

Nerve injuries can have long-lasting effects on the immune system that appear to differ between males and females, according to preclinical research from McGill University.

5 Nov 2025

While politicos dispense blame, these doctors aim to take shame out of medicine

The distress that Will Bynum later recognized as shame settled over him nearly immediately.

5 Nov 2025

AI helps detect early signs of alcoholism in firefighters with 80% accuracy

A deep learning model using brain scans and tests predicts alcohol use disorder risk in firefighters, enhancing mental health strategies in high-stress jobs.

5 Nov 2025

People with traumatic spinal cord injuries at higher risk of developing chronic health problems

A new study by investigators from Mass General Brigham shows that patients with traumatic spinal cord injuries (TSCI) are at a higher risk of developing a myriad of chronic health problems, regardless of age, location of the injury and prior health status.

4 Nov 2025

Loud noise exposure worsens motor deficits in Parkinson’s disease model

In the development of Parkinson's disease, it may not be a good idea to turn the amp to 11. High-volume noise exposure produced motor deficits in a mouse model of early-stage Parkinson's disease, and established a link between the auditory processing and movement areas of the brain, according to a study published November 4th in the open-access journal PLOS Biology by Pei Zhang from the Huazhong University of Science and Technology in Wuhan, China, and colleagues.

4 Nov 2025

Living near cannabis stores linked to more frequent use and less heavy drinking

A statewide study of more than 60,000 adult Oregonians shows that living near cannabis retail stores is associated with a greater tendency toward frequent cannabis use but a lower likelihood of heavy alcohol consumption.

4 Nov 2025

Study finds high intake of ultra-processed foods tied to reduced DNA methylation

Women who consumed more ultra-processed foods (UPFs) showed distinct DNA methylation patterns, mostly reduced across key gene regions. These exploratory findings suggest that high UPF intake may influence gene regulation through epigenetic mechanisms.

4 Nov 2025

Do GLP-1 drugs cause cancer? New review says no, may even protect

A comprehensive review in The Journal of Clinical Investigation finds no overall link between GLP-1 receptor agonists and increased cancer risk, countering early safety concerns. Instead, evidence suggests possible protective effects for certain cancers, supported by metabolic and immune-modulating mechanisms.

4 Nov 2025

GLP-1 drugs calm inflammation beyond diabetes and weight loss

This Journal of Clinical Investigation review describes how glucagon-like peptide-1 (GLP-1)–based medicines reduce systemic and tissue inflammation through both weight-dependent and weight-independent mechanisms. It details preclinical and clinical evidence linking GLP-1 receptor activation to cardiovascular, renal, hepatic, neural, and joint anti-inflammatory effects while outlining uncertainties and future research needs.

4 Nov 2025

Three health tech innovators push boundaries to build a brighter future of cardiovascular care

As digital health technologies gain momentum, research is finding that more people are open to artificial intelligence (AI) supported health interventions when those are backed by clinical expertise and rooted in evidence-based guidelines.

4 Nov 2025

New review illuminates the intricate connections between gut microbiota and sleep regulation

A comprehensive review published today in Brain Medicine illuminates the intricate connections between gut microbiota and sleep regulation, establishing the microbiota-gut-brain axis as a critical pathway in understanding and potentially treating sleep disorders.

4 Nov 2025

Stress hormones may silence crucial neuronal genes through specific RNA molecules

What if the brain's response to stress could be read not in fleeting neurotransmitter bursts, but in the quieting of genes deep inside chromatin? Researchers at the University of Alabama at Birmingham have now shown that stress hormones may silence crucial neuronal genes through an unexpected class of RNA molecules that operate not by encoding proteins, but by reshaping the genome's architecture.

4 Nov 2025

Gut bacteria in toddlers may influence anxiety and depression years later

This study links childhood gut microbiome to brain connectivity, highlighting its role in internalizing symptoms like anxiety and depression later in life.

4 Nov 2025

Mapping how the heart heals after a heart attack

Over the course of evolution, the human heart has largely lost its ability to regenerate. Our distant ancestors were not afflicted by heart attacks - a condition that emerged primarily with modern lifestyles marked by poor diet, obesity, and other cardiovascular risk factors.

3 Nov 2025

How walnuts combat inflammation and oxidative stress in the body

This review in Food Science & Nutrition synthesizes evidence showing that walnuts (Juglans regia L.) exert potent antioxidant, anti-inflammatory, apoptosis-regulatory, and immunomodulatory effects through bioactive compounds influencing mitochondrial, cytokine, and redox pathways.

3 Nov 2025

Large-scale foundation model reconstructs how cells interact within tissues

Researchers at Helmholtz Munich and the Technical University of Munich (TUM) have developed Nicheformer, the first large-scale foundation model that integrates single-cell analysis with spatial transcriptomics.

3 Nov 2025

Heated tobacco and cigarettes cause the same gut and vascular damage, study finds

Italian researchers found that both heated tobacco products (HTPs) and conventional cigarettes trigger oxidative stress, endotoxemia, and gut barrier disruption in adults and children. The findings challenge the perception that HTPs are a safer alternative to smoking.

3 Nov 2025

AI algorithm paired with ECG sensors can accurately detect structural heart diseases

An artificial intelligence (AI) algorithm paired with the single-lead electrocardiogram (ECG) sensors on a smartwatch accurately diagnosed structural heart diseases, such as weakened pumping ability, damaged valves or thickened heart muscle, according to a preliminary study to be presented at the American Heart Association's Scientific Sessions 2025.

3 Nov 2025

Long-term use of melatonin supplements linked to higher risk of heart failure and death

Long-term use of melatonin supplements, often used to promote sleep and address insomnia, was associated with a higher risk of heart failure diagnosis, heart failure hospitalization and death from any cause in chronic insomnia, according to a preliminary study to be presented at the American Heart Association's Scientific Sessions 2025.

3 Nov 2025

Healthy lifestyle habits plus GLP-1 RA drugs can improve heart health of people with Type 2 diabetes

People with Type 2 diabetes who combined healthy lifestyle habits with GLP-1 receptor agonist (GLP-1 RA) medications had a greater reduction in risk of major adverse cardiovascular events, including heart attack, stroke or cardiovascular disease death, compared to people only taking the medication, according to a preliminary study to be presented at the American Heart Association's Scientific Sessions 2025.

3 Nov 2025

Chronic News and Research

Nerve injuries found to affect the entire immune system in unexpected ways

While politicos dispense blame, these doctors aim to take shame out of medicine

AI helps detect early signs of alcoholism in firefighters with 80% accuracy

People with traumatic spinal cord injuries at higher risk of developing chronic health problems

Loud noise exposure worsens motor deficits in Parkinson’s disease model

Living near cannabis stores linked to more frequent use and less heavy drinking

Study finds high intake of ultra-processed foods tied to reduced DNA methylation

Do GLP-1 drugs cause cancer? New review says no, may even protect

GLP-1 drugs calm inflammation beyond diabetes and weight loss

Three health tech innovators push boundaries to build a brighter future of cardiovascular care

New review illuminates the intricate connections between gut microbiota and sleep regulation

Stress hormones may silence crucial neuronal genes through specific RNA molecules

Gut bacteria in toddlers may influence anxiety and depression years later

Mapping how the heart heals after a heart attack

How walnuts combat inflammation and oxidative stress in the body

Large-scale foundation model reconstructs how cells interact within tissues

Heated tobacco and cigarettes cause the same gut and vascular damage, study finds

AI algorithm paired with ECG sensors can accurately detect structural heart diseases

Long-term use of melatonin supplements linked to higher risk of heart failure and death

Healthy lifestyle habits plus GLP-1 RA drugs can improve heart health of people with Type 2 diabetes

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Bringing real-time analytics to downstream bioprocess monitoring

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Evaluating new approaches for rare disease genomics

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