Precision Medicine News and Research

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City Of Hope builds cloud-based data commons platform for observational study

A $12 million federal grant enabled City of Hope and collaborators to deploy a novel cloud-computing platform, making an immense amount of data from a historic 25-year study more accessible and user-friendly.

5 Mar 2020

New collapsible basket technology has big advantages for drug discovery, personalized medicine

A drug discovery scientist typically screens up to 10,000 compounds in the early stages of developing one FDA approved drug. During this high-throughput screening, candidate compounds are initially tested on cell and tissue samples.

4 Mar 2020

Personalized approach in IVF increases success rate

Becoming pregnant can be a lengthy and stressful process for one in every six couples. As fertility treatment protocols are based on the "average woman", approximately 30 per cent of patients need a personalised approach in IVF.

4 Mar 2020

New method maps 3D forces exerted by tiny cell clusters

A team of researchers has developed a new technique to map the three-dimensional forces that clusters of human cells exert on their surrounding environment. The method could potentially help scientists better understand how tissue forms, how wounds heal or how tumors spread.

3 Mar 2020

Scientists find link between immune system and high blood pressure in patients with CKD

Detecting threats, sending out response molecules, and altering gene expression--our immune system works tirelessly day and night to protect us from invading pathogens and maintain general health and wellbeing.

3 Mar 2020

Targeted therapy may increase overall survival in patients with pancreatic cancer

Results from 46 patients given treatments that target specific molecular changes in tumor cells suggest that these therapies could help patients with pancreatic cancer whose tumors harbor those changes survive an extra year.

2 Mar 2020

New tool allows researchers to peer into live tissue of the fruit fly gut

They say a picture is worth 1,000 words. But what about a real-time window into the complexity of the gastrointestinal system?

2 Mar 2020

Challenges for translating pharmacomicrobiomics to personalized medicine

A new Commentary identifies three actionable challenges for translating pharmacomicrobiomics to personalized medicine in 2020.

2 Mar 2020

WFIRM scientists develop miniature organ model to test drug toxicity

Scientists at the Wake Forest Institute for Regenerative Medicinehave developed the world's most sophisticated laboratory model of the human body, creating a system of miniaturized organs that can be used to detect harmful and adverse effects of drugs before they are prescribed to patients.

2 Mar 2020

New research cluster aims to use mass spectrometry to provide insights in systems medicine

The Mainz University Medical Center and Johannes Gutenberg University Mainz are establishing the interdisciplinary research cluster entitled "Data-Independent Acquisition-based Systems Medicine (DIASyM): Mass Spectrometry for High-Throughput Deep Phenotyping of Heart Failure Syndrome".

28 Feb 2020

Coriell researchers find new genetic indicator of obesity risk

Obesity is among the most common complex diseases in the United States and has been a stubborn public health challenge for decades. Its causes are wide ranging, but genetic heritability is increasingly understood to be an influential factor in determining a person's risk for the disease.

23 Feb 2020

A step towards precision medicine for the management of monogenic diabetes

Diabetes affects more than 400 million people worldwide and is a major public health problem. Although commonly referred to as a single disease, it actually constitutes a group of metabolic disorders with hyperglycemia as a common feature. Of all its forms, monogenic diabetes - due to a mutation in one of the genes involved in the management of blood sugar levels - affects 1% to 4% of all cases of diabetes.

22 Feb 2020

Researchers map the cellular diversity of entire salivary gland tumors

What goes on inside and between individual cells during the very earliest stages of tumor development? Single cell sequencing technologies and a mouse model have enabled researchers to comprehensively map the cellular diversity of whole salivary gland tumors and trace the path of cancer stem cells.

20 Feb 2020

BPA-free plastic products aren't safe for people to use, scientists warn

Using "BPA-free" plastic products could be as harmful to human health -- including a developing brain -- as those products that contain the controversial chemical, suggest scientists in a new study led by the University of Missouri and published in the Proceedings of the National Academy of Sciences.

19 Feb 2020

Association between HMO concentrations and infant weight, body composition

Breastfeeding affects infant growth and, researchers have found, helps prevent obesity, both in childhood and later in life. However, the components of breast milk responsible for these beneficial effects remain mostly a mystery.

18 Feb 2020

Detailed maps of breast cancer reveal how genetic changes shape the tumor landscape

Scientists have created one of the most detailed maps of breast cancer ever achieved, revealing how genetic changes shape the physical tumor landscape, according to research funded by Cancer Research UK and published in Nature Cancer today (Monday).

17 Feb 2020

Revolutionary SPion technology enables remote analysis with mass spectrometry

Trace Matters Scientific today introduced SPion -a revolutionary technology that enables the world's most sensitive and versatile remote analysis with mass spectrometry.

16 Feb 2020

AI used to instantly and accurately measure blood flow

Artificial intelligence has been used for the first time to instantly and accurately measure blood flow, in a study led by UCL and Barts Health NHS Trust.

14 Feb 2020

Study provides a detailed molecular snapshot of endometrial cancer

A study published Feb. 13 in Cell provides an unprecedented look at the dozens of molecular steps that occur to bring about endometrial cancer, commonly known as uterine cancer.

14 Feb 2020

Treating soft tissue sarcoma with shorter radiation treatment found to be safe, effective

A new study led by researchers at the UCLA Jonsson Comprehensive Cancer Center found that treating soft tissue sarcoma with radiation over a significantly shorter period of time is safe, and likely just as effective, as a much longer conventional course of treatment.

13 Feb 2020

Precision Medicine News and Research

City Of Hope builds cloud-based data commons platform for observational study

New collapsible basket technology has big advantages for drug discovery, personalized medicine

Personalized approach in IVF increases success rate

New method maps 3D forces exerted by tiny cell clusters

Scientists find link between immune system and high blood pressure in patients with CKD

Targeted therapy may increase overall survival in patients with pancreatic cancer

New tool allows researchers to peer into live tissue of the fruit fly gut

Challenges for translating pharmacomicrobiomics to personalized medicine

WFIRM scientists develop miniature organ model to test drug toxicity

New research cluster aims to use mass spectrometry to provide insights in systems medicine

Coriell researchers find new genetic indicator of obesity risk

A step towards precision medicine for the management of monogenic diabetes

Researchers map the cellular diversity of entire salivary gland tumors

BPA-free plastic products aren't safe for people to use, scientists warn

Association between HMO concentrations and infant weight, body composition

Detailed maps of breast cancer reveal how genetic changes shape the tumor landscape

Revolutionary SPion technology enables remote analysis with mass spectrometry

AI used to instantly and accurately measure blood flow

Study provides a detailed molecular snapshot of endometrial cancer

Treating soft tissue sarcoma with shorter radiation treatment found to be safe, effective

Event guide: The 4th Precision Medicine in Inflammatory Bowel Disease Summit eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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