Precision Medicine News and Research

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21-gene recurrence score can aid in radiation decision-making, shows study

A new study shows that a test physicians commonly used to guide chemotherapy treatment for post-breast cancer surgery patients may also help them decide whether radiation therapy may be of benefit.

10 Jan 2020

New method uses MRI, machine learning to forecast genetic mutations in glioma tumors

Researchers at Osaka University have developed a computer method that uses magnetic resonance imaging (MRI) and machine learning to rapidly forecast genetic mutations in glioma tumors, which occur in the brain or spine. The work may help glioma patients to receive more suitable treatment faster, giving better outcomes.

9 Jan 2020

ToxPoint article highlights alternative mechanism to bring focus to major issues in toxicology

The new year has brought with it advances to the Society of Toxicology's official journal, Toxicological Sciences, some of which are reflected in the January 2020 issue - Volume 173, Issue 1.

9 Jan 2020

Study shows how sewage plants can remove pharmaceuticals from wastewater

Corals depend on their symbiotic relationships with the algae that they host. But how do they keep algal population growth in check?

9 Jan 2020

Research project leverages big data to close the gap on cognitive decline and healthy aging

A new research project at the University of Arizona Center for Innovation in Brain Science will apply a big-data approach, using bioinformatics and computational modeling, to better understand the systems biology of Alzheimer's and other neurodegenerative diseases.

8 Jan 2020

ISPOR identifies top 10 HEOR trends that will shape and influence healthcare

ISPOR - the professional society for health economics and outcomes research (HEOR), announced the publication of its 2020 Top 10 HEOR Trends report.

7 Jan 2020

Palmetto GBA now covers Genomic Testing Cooperative’s solid tumor molecular profile

Genomic Testing Cooperative, LCA announced that the Medicare Administrative Contractor Palmetto GBA (MolDx) has established coverage for its solid tumor molecular profile.

7 Jan 2020

Dana-Farber Cancer Institute to create Chen-Huang Center for EGFR Mutant Lung Cancers

Dana-Farber Cancer Institute will create the Chen-Huang Center for EGFR (epidermal growth factor receptor) Mutant Lung Cancers to stimulate research, promote clinical trials, and strengthen the Institute's capabilities for studying and treating lung cancer.

7 Jan 2020

New brain tumor research could improve patient diagnosis, treatment options

New research on brain tumours could improve patient diagnosis and treatment options as part of a precision medicine approach. Brain tumours are the leading cause of cancer deaths in children and adults under the age of 40, with 16,000 people in the UK diagnosed with a brain tumour each year.

7 Jan 2020

VA researchers find new evidence on the underlying biological causes of anxiety

In the largest genetic study on anxiety to date, VA researchers found new evidence on the underlying biological causes of the disorder.

7 Jan 2020

DNA tests to provide rapid diagnosis of rare diseases in critically ill infants

NHS England is will now provide new DNA testing that can rapidly diagnose rare diseases in critically ill babies and children.

3 Jan 2020

Tau-protein better predicts brain atrophy in Alzheimer's patients than amyloid plaques

Brain imaging of pathological tau-protein "tangles" reliably predicts the location of future brain atrophy in Alzheimer's patients a year or more in advance, according to a new study by scientists at the UC San Francisco Memory and Aging Center. In contrast, the location of amyloid "plaques," which have been the focus of Alzheimer's research and drug development for decades, was found to be of little utility in predicting how damage would unfold as the disease progressed.

2 Jan 2020

Scientists discover potential drug compounds that target common type of liver cancer

Scientists from the Cancer Science Institute of Singapore at the National University of Singapore, and the Agency for Science, Technology and Research (A*STAR)'s Genome Institute of Singapore have discovered four potential drug compounds that target hepatocellular carcinoma, the most common type of liver cancer.

30 Dec 2019

Study uncovers novel targetable axis in mesothelioma patients

A collaborative study of researchers from Thomas Jefferson University, Sbarro Institute for Cancer Research and Molecular Medicine of Temple University, University of Siena, and from the Spanish Center for the Applied Medical Research of the University of Navarra have discovered a novel targetable axis in mesothelioma patients.

26 Dec 2019

Researchers develop powerful computer algorithm for large-scale genomic analysis

Haplotypes are a set of genetic variations that, located side by side on the same chromosome, are transmitted in a single group to the next generation. Their examination makes it possible to understand the heritability of certain complex traits, such as the risk of developing a disease.

20 Dec 2019

Combined datasets can expedite the discovery and development of new cancer drugs

A comprehensive map of genes necessary for cancer survival is one step closer, following the validation of the two largest CRISPR-Cas9 genetic screens in 725 cancer models, across 25 different cancer types.

20 Dec 2019

Data results of NCI-MATCH trial in tumors with DNA mismatch repair deficiencies

Final results are published from an evaluation of 42 patients treated with the immune checkpoint inhibitor nivolumab in the large multi-arm precision medicine trial, NCI-Molecular Analysis for Therapy Choice (NCI-MATCH or EAY131).

20 Dec 2019

Artificial 'inclusion bodies' developed for sustained release of therapeutic proteins

Precision medicine is becoming increasingly important, achieving to create more efficient personalized therapies for each patient and innovative pharmacological developments.

19 Dec 2019

Different mutations in a single gene can have myriad effects on a person's health

Mount Sinai researchers have found that different mutations in a single gene can have myriad effects on a person's health, suggesting that gene therapies may need to do more than just replenish the missing or dysfunctional protein the gene is supposed to encode, according to a study published in Nature Genetics in November.

18 Dec 2019

Olympus and Ultivue Announce Comarketing Agreement for Leading-Edge Fluorescent Multiplexing Solution

Olympus SLIDEVIEW™ VS200 slide scanner and Ultivue UltiMapper™ reagents meet the changing needs of the scientific community

From Evident Corporation - Life Sciences 18 Dec 2019

Precision Medicine News and Research

21-gene recurrence score can aid in radiation decision-making, shows study

New method uses MRI, machine learning to forecast genetic mutations in glioma tumors

ToxPoint article highlights alternative mechanism to bring focus to major issues in toxicology

Study shows how sewage plants can remove pharmaceuticals from wastewater

Research project leverages big data to close the gap on cognitive decline and healthy aging

ISPOR identifies top 10 HEOR trends that will shape and influence healthcare

Palmetto GBA now covers Genomic Testing Cooperative’s solid tumor molecular profile

Dana-Farber Cancer Institute to create Chen-Huang Center for EGFR Mutant Lung Cancers

New brain tumor research could improve patient diagnosis, treatment options

VA researchers find new evidence on the underlying biological causes of anxiety

DNA tests to provide rapid diagnosis of rare diseases in critically ill infants

Tau-protein better predicts brain atrophy in Alzheimer's patients than amyloid plaques

Scientists discover potential drug compounds that target common type of liver cancer

Study uncovers novel targetable axis in mesothelioma patients

Researchers develop powerful computer algorithm for large-scale genomic analysis

Combined datasets can expedite the discovery and development of new cancer drugs

Data results of NCI-MATCH trial in tumors with DNA mismatch repair deficiencies

Artificial 'inclusion bodies' developed for sustained release of therapeutic proteins

Different mutations in a single gene can have myriad effects on a person's health

Olympus and Ultivue Announce Comarketing Agreement for Leading-Edge Fluorescent Multiplexing Solution

Editorial Focus eBook - Proteomics eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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