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New long-acting delivery system has potential to lessen side effects from NRTIs

An HIV diagnosis, while no longer constituting a death sentence, brings with it a lifetime, daily regimen of medication to help continually combat the virus.

27 Mar 2018

New intervention aims to improve treatment adherence among teen kidney transplant recipients

Learning to become self-sufficient and responsible is part of life's journey through the teen and young adult years. Mistakes are often made, and lessons are learned. However, for young kidney-graft patients, any mistake or failure in keeping to their strict immunosuppressive therapy can lead to tragic results.

27 Mar 2018

Study uncovers genetic trigger that may help the brain to recover from stroke, other injuries

Scientists have found a genetic trigger that may improve the brain's ability to heal from a range of debilitating conditions, from strokes to concussions and spinal cord injuries.

27 Mar 2018

Menopausal hormone therapy reduces abdominal fat tissue in women

Women who undergo hormone therapy to relieve menopausal symptoms tend to have less fat tissue, particularly in the abdomen, than other menopausal women, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

27 Mar 2018

Researchers measure whether transcranial direct current stimulation generates EFs in deep brain areas

A defining characteristic of stroke is the loss of motor control due to structural damage in specific brain areas. In fact, motor impairments (or deficits) are the number one complication after stroke.

27 Mar 2018

Testosterone therapy not linked to rise in estrogen levels among transgender men

Testosterone therapy is not associated with a rise in estrogen levels among transgender men, according to a new study led by Boston Medical Center. In fact, the researchers observed an initial decline in estrogen levels, which later stabilized and remained within the normal range during the study's six-year period.

27 Mar 2018

Cell-penetrating 'nanodrills' could be new platform for intracellular drug delivery

Researchers at Oregon State University and Oregon Health & Science University have created new nanomaterials able to cross cell membranes, establishing a novel platform for the intracellular delivery of molecular drugs and other cargo.

27 Mar 2018

Johns Hopkins researchers make great strides in understanding biology behind pulmonary hypertension

Working with cells that line the innermost layer of the blood vessels, Johns Hopkins investigators say they have made a leap forward in understanding the underlying biology behind pulmonary hypertension, a dangerous type of high blood pressure in lungs that ultimately leads to right heart failure and death.

27 Mar 2018

Stigma associated with Alzheimer's may prevent people from getting early diagnosis, treatment

Stigma associated with Alzheimer's disease may be an obstacle for individuals to seek information about their risk of developing Alzheimer's disease and to participate in clinical studies that discover potential therapies.

27 Mar 2018

Combination therapy effectively induces tumor cell death and reduces spread of breast cancer

Each day, normal human cell tissues express a protein known as p53 that wages war against potential malignancies. However, between 30 and 40 percent of human breast cancers express a defective (mutant) form of p53 that helps cancer cells proliferate and grow.

27 Mar 2018

Study identifies genetic factors linked to severity of acute viral bronchiolitis

A scientific study conducted at the State University of Campinas (UNICAMP) in São Paulo State, Brazil, has identified genetic factors associated with the severity of acute viral bronchiolitis. The study was supported by the Sao Paulo Research Foundation - FAPESP. Its results were published in the journal Gene.

27 Mar 2018

Researchers aim to accurately identify aggressive oropharyngeal cancers

The Case Western Reserve-led research team will analyze computerized images of tissue samples for patterns which could become "biomarkers," or predictors, for determining relative risk for recurrence in one particularly common type of head and neck cancers.

27 Mar 2018

Changing schedules of targeted therapy for melanoma could improve outcomes

Skin melanoma, a particularly insidious cancer, accounts for the vast majority skin cancer deaths and is one of the most common cancers in people under 30.

26 Mar 2018

New device achieves 92% accuracy in detecting patients with severe stroke

A new device worn like a visor can detect emergent large-vessel occlusion in patients with suspected stroke with 92 percent accuracy, report clinical investigators at the Medical University of South Carolina, Mount Sinai, the University of Tennessee Health Sciences Center and elsewhere in an article published online on March 6, 2018, in the Journal of Neurointerventional Surgery.

26 Mar 2018

Adjuvant therapy may not improve survival for rare cancers

A recent study found that adjuvant therapy following surgical removal of a rare form of gastrointestinal tumor has no effect on survival rates for patients.

26 Mar 2018

Using VR to Go Back in Time for Those Living with Alzheimer's

Currently, there are an estimated 46 million people worldwide living with dementia. There is currently no cure, and no way to prevent the onset of dementia. The Wayback Project was created by a group of friends and former colleagues who wanted to create virtual reality films that allow patients to go 'back in time'.

26 Mar 2018

Study finds low treatment rates for people with elevated cholesterol levels

Less than 40 percent of people with severe elevations in cholesterol are being prescribed appropriate drug treatment, according to a nationally representative study reported in the American Heart Association's journal Circulation.

26 Mar 2018

Increasing prevalence of functional mitral regurgitation related to severity of heart failure

One potential therapeutic concept for treating heart failure besides guideline directed medical therapy, is to correct any concomitant severe mitral valve insufficiency (mitral regurgitation). Despite numerous treatment options being available, it is still not clear which patients will benefit most from such an intervention.

26 Mar 2018

Two immunotherapies used together for the first time to fight against solid tumors

Two immunotherapies - one that enables the T-cells a patient already has to better attack a tumor and another that can produce an independent and vigorous immune response - are being given together for the first time to help more patients wage a stronger war on a wide range of solid tumors, researchers say.

26 Mar 2018

Adjuvant therapy after surgical removal of rare tumors may not provide survival benefit

Results of an analysis from the University of Cincinnati College of Medicine show that additional therapy, or adjuvant therapy, delivered after surgical removal of a rare type of gastrointestinal tumor does not increase survival rates for patients.

26 Mar 2018

Therapy News and Research

New long-acting delivery system has potential to lessen side effects from NRTIs

New intervention aims to improve treatment adherence among teen kidney transplant recipients

Study uncovers genetic trigger that may help the brain to recover from stroke, other injuries

Menopausal hormone therapy reduces abdominal fat tissue in women

Researchers measure whether transcranial direct current stimulation generates EFs in deep brain areas

Testosterone therapy not linked to rise in estrogen levels among transgender men

Cell-penetrating 'nanodrills' could be new platform for intracellular drug delivery

Johns Hopkins researchers make great strides in understanding biology behind pulmonary hypertension

Stigma associated with Alzheimer's may prevent people from getting early diagnosis, treatment

Combination therapy effectively induces tumor cell death and reduces spread of breast cancer

Study identifies genetic factors linked to severity of acute viral bronchiolitis

Researchers aim to accurately identify aggressive oropharyngeal cancers

Changing schedules of targeted therapy for melanoma could improve outcomes

New device achieves 92% accuracy in detecting patients with severe stroke

Adjuvant therapy may not improve survival for rare cancers

Using VR to Go Back in Time for Those Living with Alzheimer's

Study finds low treatment rates for people with elevated cholesterol levels

Increasing prevalence of functional mitral regurgitation related to severity of heart failure

Two immunotherapies used together for the first time to fight against solid tumors

Adjuvant therapy after surgical removal of rare tumors may not provide survival benefit

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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