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Dopamine therapy improves cognitive function in patients with mild-to-moderate Alzheimer's

A study supported by the Alzheimer's Drug Discovery Foundation and published today in JAMA Network Open provides the first evidence that rotigotine, a drug that acts on dopamine transmission in the brain, improves cognitive function in patients with mild-to-moderate Alzheimer's disease.

15 Jul 2020

COVID-19 rates among health care workers drop at Mass General Brigham after universal masking

In March of 2020, Mass General Brigham implemented a new policy: everyone working at the hospitals would be required to wear a surgical mask.

15 Jul 2020

States slow to implement social distancing measures saw higher COVID-19 mortality

As the COVID-19 pandemic spread across the United States, governments at the state and local levels issued emergency declarations and shut down schools.

15 Jul 2020

New test uses a single drop of blood to rapidly detect radiation sickness

A new proof-of-concept study reports evidence that a new testing method has the potential to rapidly identify radiation sickness based on biomarkers measured through a single drop of blood.

15 Jul 2020

New immune profiles could help predict disease trajectory in severe COVID-19 patients

Researchers from the Penn Institute of Immunology discovered three distinct immune responses to the SARS-CoV2 infection that could help predict the trajectory of disease in severe COVID-19 patients and may ultimately inform how to best treat them.

15 Jul 2020

Study explains why fetuses and newborns are mostly spared by COVID-19

Amid the coronavirus pandemic, it has been previously suggested that the most vulnerable individuals to developing severe coronavirus disease (COVID-19) include the elderly, those with underlying health conditions, and those who have weakened immune systems.

15 Jul 2020

Buck researchers investigate ketone bodies as possible therapeutic against COVID-19

Given the disproportionate impact that COVID-19 has on older adults in terms of death and lasting disability, and the impact of common aging-related comorbidities like diabetes and cardiovascular disease, Buck Institute professor and practicing geriatrician John Newman, MD, PhD, can make a compelling argument that those infected with the SARS-CoV2 virus are suffering from an aging-related disease, no matter how old they are when they get infected.

15 Jul 2020

Promising new CAR T cell therapy results in exceptional patient recovery

In a clinical trial evaluating a novel immunotherapy option for cancer treatment, a child with rhabdomyosarcoma, a form of muscle cancer, that had spread to the bone marrow, showed no detectable cancer following treatment with chimeric antigen receptor (CAR) T cells that were engineered to target the HER2 protein on the surface of the cancer cells.

15 Jul 2020

Study identifies possible factors to predict severe toxicities in CAR T patients

Chimeric antigen receptor T-cell therapy (CAR T) has proved to be a valuable treatment option for patients with lymphoma who have failed other therapies. In clinical trials, the cellular immunotherapy was shown to provide durable remissions for nearly 40% of large B cell lymphoma patients.

15 Jul 2020

UC study tests efficacy of immune regulating drug in treating patients with COVID-19 pneumonia

Researchers at the University of Cincinnati are testing a commonly used drug, called sirolimus, to determine its safety and efficacy in treating hospitalized patients with COVID-19 pneumonia in the trial.

15 Jul 2020

Anaplastic large cell lymphoma: Defense mechanism against certain drugs promotes cancer growth

A general problem encountered in cancer therapy is that many patients develop resistance to a drug over the course of treatment.

15 Jul 2020

New trial investigates if prostate cancer drug can be used to treat COVID-19

In a new trial, Swedish researchers will investigate if a medicine normally used to treat prostate cancer can also be used to treat COVID-19 in patients.

15 Jul 2020

Quest Diagnostics Health Trends study: HPV screening less likely to detect cervical cancer than cotesting

A Health Trends study from researchers at Quest Diagnostics and the University of Pittsburgh Medical Center provides new evidence that the HPV screening test is significantly less likely to detect cervical cancer and precancer than cotesting, a method which combines HPV and Pap testing using the same specimen.

15 Jul 2020

10x Genomics launches Chromium Single Cell Immune Profiling v2 product to fight COVID-19

10x Genomics strengthened the research toolkit of scientists around the globe today with the launch of its Chromium Single Cell Immune Profiling v2 product.

15 Jul 2020

World's first technology aims to help diagnose, treat and manage people with cystic fibrosis

World-first research led by Monash University could hold the key to better monitoring and treatment of lung disease associated with cystic fibrosis (CF) – a condition thousands of people are diagnosed with each year.

15 Jul 2020

Proportion of healthcare-associated infections is higher than believed

One in four inpatients with influenza in a given season showed signs of having become infected during care. This is clear from a University of Gothenburg thesis about the spread of influenza in hospitals and how this problem can be remedied.

15 Jul 2020

Viral load peaks in early stages of COVID-19 disease, shows study

In a retrospective study, investigators from New York University Langone Health found that the quantity of SARS-CoV-2 (viral load) collected from patients in the emergency department is significantly higher in patients with fewer or milder symptoms who did not require hospitalization--the opposite of what might be expected.

15 Jul 2020

"Winter is coming," warn UK COVID-19 experts

The famous line from "Game of Thrones" about approaching dangers this winter may prove to be accurate, say, scientists in a new report. The researchers state that a second wave of infection could hit the United Kingdom this winter, and this would be worse than the first wave taking as many as 120,000 lives.

14 Jul 2020

Analysis of maternal deaths in Mozambique reveals major diagnostic error in most cases

An analysis of a series of maternal deaths in Maputo's central hospital, in Mozambique, reveals a major diagnostic error in almost 40% of the deaths.

14 Jul 2020

One in three young adults at a higher risk of severe COVID-19 due to smoking, vaping

Now, a new study shows that about one in three young adults may be at risk of severe COVID-19 due to smoking and vaping habits.

14 Jul 2020

Hospital News and Research

Dopamine therapy improves cognitive function in patients with mild-to-moderate Alzheimer's

COVID-19 rates among health care workers drop at Mass General Brigham after universal masking

States slow to implement social distancing measures saw higher COVID-19 mortality

New test uses a single drop of blood to rapidly detect radiation sickness

New immune profiles could help predict disease trajectory in severe COVID-19 patients

Study explains why fetuses and newborns are mostly spared by COVID-19

Buck researchers investigate ketone bodies as possible therapeutic against COVID-19

Promising new CAR T cell therapy results in exceptional patient recovery

Study identifies possible factors to predict severe toxicities in CAR T patients

UC study tests efficacy of immune regulating drug in treating patients with COVID-19 pneumonia

Anaplastic large cell lymphoma: Defense mechanism against certain drugs promotes cancer growth

New trial investigates if prostate cancer drug can be used to treat COVID-19

Quest Diagnostics Health Trends study: HPV screening less likely to detect cervical cancer than cotesting

10x Genomics launches Chromium Single Cell Immune Profiling v2 product to fight COVID-19

World's first technology aims to help diagnose, treat and manage people with cystic fibrosis

Proportion of healthcare-associated infections is higher than believed

Viral load peaks in early stages of COVID-19 disease, shows study

"Winter is coming," warn UK COVID-19 experts

Analysis of maternal deaths in Mozambique reveals major diagnostic error in most cases

One in three young adults at a higher risk of severe COVID-19 due to smoking, vaping

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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