Therapy News and Research

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Antimicrobial peptides are promising alternative for combatting antimicrobial resistance

Overuse of antibiotics has led to the spread of multi-resistant bacteria that do not respond to conventional treatments.

29 May 2018

Researchers identify novel target for bladder cancer

Researchers have identified an olfactory receptor in the human bladder that could prove useful in the diagnosis and treatment of bladder cancer.

29 May 2018

Genome dark matter provides clues to fighting prostate cancer

Through studying the dark matter of the human genome, a team from the University of Michigan has shed light on how the hormone androgen drives prostate cancer and suggested a potential target for future therapy.

28 May 2018

NIH summit presents recommendations to accelerate treatment development for Alzheimer's disease

Experts from government, academia, industry, non-profit organizations put forward recommendations that provide a roadmap for an integrated, multidisciplinary research agenda necessary to inform priorities for Alzheimer's disease and related dementias.

26 May 2018

Causes and treatment of acute heart failure vary by region, registry shows

Triggers of acute heart failure vary globally, according to late breaking results from the REPORT-HF registry presented today at Heart Failure 2018 and the World Congress on Acute Heart Failure, a European Society of Cardiology Congress.

26 May 2018

Researchers reveal potent new mechanism of action for treatment of IBD

Professor Akiyoshi Fukamizu's research group of Life Science Center for Survival Dynamics, University of Tsukuba, Eisai Co., Ltd. and its gastrointestinal business subsidiary EA Pharma Co., Ltd. have revealed a mechanism in which an analogue (ER-464195-01) of Eisai's in-house discovered E6007 inhibits integrin activation by dissociating interaction between calreticulin (CRT) and integrin α 4 (ITGA4), suppressing adhesion and infiltration of leukocytes overall.

25 May 2018

New findings could help fine-tune treatment for cancer patients

Cancer therapies that cut off blood supply to a tumor could be more effective in combination with existing chemotherapeutic drugs - according to new research from the University of East Anglia.

25 May 2018

Study finds early antibiotic initiation for majority of premature infants

Most premature infants, who are at risk for sepsis but who may not have a culture confirmation of infection, continue to receive early antibiotics in the first few days of life, a finding that suggests neonatal antibiotic stewardship efforts are needed to help clinicians identify infants at lowest risk for infection to avoid unnecessary antibiotic exposure.

25 May 2018

Cancer cells co-opt pain-sensing 'neural channel' to increase tolerance against oxidative stress

Anyone who's taken a bite of a sandwich with too much spicy mustard or a piece of sushi with too much wasabi can attest to the tear-inducing sensation these condiments can cause. These loud warnings to the nervous system of exposure to potentially harmful chemicals are triggered by TRPA1, a calcium channel protein sometimes referred to as the "wasabi receptor."

25 May 2018

Delayed lactate measurements in sepsis patients increase risk of in-hospital death

The rising incidence of sepsis, a leading cause of in-hospital death, has prompted the Centers for Medicare and Medicaid Services to issue protocols known as care bundles to standardize and improve sepsis care.

25 May 2018

Study reveals new protective mechanism for tumor cells in breast cancer

Greater knowledge of the mechanisms that contribute to the survival of tumor cells is key to vanquishing them.

25 May 2018

BMC receives $13.5 million award to test methods for delivering childhood anxiety treatment

Boston Medical Center has been approved for a $13.5 million award by the Patient-Centered Outcomes Research Institute to test the efficacy of two different methods of delivering cognitive behavioral therapy - face to face or online - to children with anxiety.

25 May 2018

FDA approves novel enzyme therapy for adults with rare and serious genetic disease

The U.S. Food and Drug Administration today approved Palynziq (pegvaliase-pqpz) for adults with a rare and serious genetic disease known as phenylketonuria (PKU).

25 May 2018

Research examines link between lower-fat diet and breast cancer overall survival

Women diagnosed with breast cancer during the Women's Health Initiative Dietary Modification trial who were following a lower-fat diet had increased breast cancer overall survival, although the increase was likely partly due to better survival from several causes of death.

24 May 2018

Home-based telehealth therapy program effective for stroke rehabilitation, shows study

In-home rehabilitation, using a telehealth system and supervised by licensed occupational/physical therapists, is an effective means of improving arm motor status in stroke survivors, according to findings presented by University of California, Irvine neurologist Steven C. Cramer, MD, at the recent 2018 European Stroke Organisation Conference in Gothenburg, Sweden.

24 May 2018

International researchers succeed in stopping growth of mesothelioma in model animals

An international team led by researchers from the Technion-Israel Institute of Technology and NYU Langone Health have succeeded in stopping the growth of mesothelioma in model animals by inhibiting the heparanase enzyme.

24 May 2018

CU research sheds light on liver disease caused by intravenous nutrition

Research by physician-scientists at the University of Colorado Anschutz Medical Campus offers hope for improved quality of life for people who rely on intravenous nutrition due to intestinal damage.

24 May 2018

Skin cream containing rapamycin reduces TSC-related facial tumors

Addressing a critical issue for people with a genetic disorder called tuberous sclerosis complex, doctors at The University of Texas Health Science Center at Houston reported that a skin cream containing rapamycin significantly reduced the disfiguring facial tumors affecting more than 90 percent of people with the condition.

23 May 2018

Scientists create small, self-contained spaces inside mammalian cells

How to install new capabilities in cells without interfering with their metabolic processes? A team from the Technical University of Munich and the Helmholtz Zentrum München have altered mammalian cells in such a way that they formed artificial compartments in which sequestered reactions could take place, allowing the detection of cells deep in the tissue and also their manipulation with magnetic fields.

23 May 2018

Mapping the Genes Responsible for Pluripotency

Dr. Atilgan Yilmaz and his team have developed a method by which they can produce haploid human embryonic stem cells from oocytes. They combined this technique with CRISPR-Cas9 to generate an atlas of the genome, containing the functions of over 18,000 genes.

23 May 2018

Therapy News and Research

Antimicrobial peptides are promising alternative for combatting antimicrobial resistance

Researchers identify novel target for bladder cancer

Genome dark matter provides clues to fighting prostate cancer

NIH summit presents recommendations to accelerate treatment development for Alzheimer's disease

Causes and treatment of acute heart failure vary by region, registry shows

Researchers reveal potent new mechanism of action for treatment of IBD

New findings could help fine-tune treatment for cancer patients

Study finds early antibiotic initiation for majority of premature infants

Cancer cells co-opt pain-sensing 'neural channel' to increase tolerance against oxidative stress

Delayed lactate measurements in sepsis patients increase risk of in-hospital death

Study reveals new protective mechanism for tumor cells in breast cancer

BMC receives $13.5 million award to test methods for delivering childhood anxiety treatment

FDA approves novel enzyme therapy for adults with rare and serious genetic disease

Research examines link between lower-fat diet and breast cancer overall survival

Home-based telehealth therapy program effective for stroke rehabilitation, shows study

International researchers succeed in stopping growth of mesothelioma in model animals

CU research sheds light on liver disease caused by intravenous nutrition

Skin cream containing rapamycin reduces TSC-related facial tumors

Scientists create small, self-contained spaces inside mammalian cells

Mapping the Genes Responsible for Pluripotency

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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