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Latest research on diagnosis and treatment of allergic diseases

Researchers are presenting more than 450 abstracts on investigational findings in the diagnosis and treatment of allergic diseases at the ACAAI Annual Meeting in Seattle, Nov. 6-11. Following are highlights of some key studies on asthma.

11 Nov 2008

Protein called TIM-3 turns off HIV-fighting T cells

In HIV-infected patients the body's immune system is unable to fight off the virus.

11 Nov 2008

Newborn neurons in the adult brain can settle in the wrong neighborhood

In a study that could have significant consequences for neural tissue transplantation strategies, researchers at the Salk Institute for Biological Studies report that inactivating a specific gene in adult neural stem cells makes nerve cells emerging from those precursors form connections in the wrong part of the adult brain.

11 Nov 2008

Simple blood test for high-sensitivity C-reactive protein is a useful marker for cardiovascular disease

This year, about 450,000 Americans will die of coronary heart disease – the leading cause of death for both men and women.

11 Nov 2008

Ewing sarcoma treatment ineffective, despite promising laboratory data

Ewing sarcoma is the second most common type of primary bone cancer seen in children and young adults.

10 Nov 2008

Santaris Pharma releases positive data on LNA-based survivin inhibitor

Santaris Pharma announced today that SPC3042, a RNA-based antisense oligonucleotide developed using the company's proprietary Locked Nucleic Acid (LNA) technology, potently blocks survivin, a key survival protein in cancer cells, in both in vitro and in vivo models of prostate cancer. Importantly, SPC3042 works synergistically with the anticancer drug paclitaxel (Taxol) in both model systems.

10 Nov 2008

New risk factor for heart disease suggests more should be on statins

Canadian scientists have discovered a new risk factor for cardiovascular disease and the significance of their discovery was so conclusive that the clinical trial was stopped before its scheduled completion date.New risk factor for heart disease suggests more should be on statins

10 Nov 2008

VIA Pharmaceuticals announces results of phase 2 trials of VIA-2291 in cardiovascular disease

VIA Pharmaceuticals, Inc. has announced the results of two Phase 2 studies of its lead drug, VIA-2291.

10 Nov 2008

T-cell-based strategy for HIV-1 vaccines still viable option

The question of whether or not to continue to pursue the development of T-cell-based HIV-1 vaccines has been a source of controversy following last year's widely publicized failure of the field's most promising candidate, a vaccine developed by Merck known as V520.

10 Nov 2008

High levels of high-sensitivity C-reactive protein found to be new risk factor for cardiovascular disease

A team of international researchers - including scientists from the McGill University Health Centre (MUHC) and McGill University - have discovered that having high levels of particular protein puts patients at increased risk of developing cardiovascular disease.

10 Nov 2008

Five key proteins form new, early-warning blood test before heart attack strikes

A team of Johns Hopkins biochemists has identified a mixed bag of five key proteins out of thousands secreted into blood draining from the heart's blood vessels that may together or in certain quantities form the basis of a far more accurate early warning test than currently in use of impending heart attack in people with severely reduced blood flow, or ischemia.

10 Nov 2008

Crestor (rosuvastatin calcium) shown to significantly reduce major cardiovascular events

New data from the JUPITER study demonstrated that Crestor (rosuvastatin calcium) 20 mg significantly reduced major cardiovascular (CV) events (defined in this study as the combined risk of myocardial infarction, stroke, arterial revascularization, hospitalization for unstable angina, or death from CV causes) by a dramatic 44% compared to placebo (p<0.001) among men and women with elevated hsCRP but low to normal cholesterol levels.

10 Nov 2008

Further evidence that angiogenesis drugs can be much more effective when combined with chemotherapy

Scientists have thought that one way to foil a tumor from generating blood vessels to feed its growth - a process called angiogenesis - was by creating drugs aimed at stopping a key vessel growth-promoting protein.

10 Nov 2008

Advances in ophthalmology

The 2008 Joint Meeting of the American Academy of Ophthalmology (Academy) and European Society of Ophthalmology (SOE), the largest and most comprehensive ophthalmic educational meeting in the world, is in session November 8 to 11 at the Georgia World Congress Center, Atlanta.

10 Nov 2008

Sydney student solves piece of the diabetes puzzle

An important piece in the diabetes puzzle which has perplexed scientists for decades has been uncovered by a Sydney PhD student at Sydney's Garvan Institute of Medical Research.

9 Nov 2008

Overnight hemodialysis dramatically improves survival

For hemodialysis patients, undergoing dialysis for eight hours overnight, three times weekly, reduces the risk of death by nearly 80 percent, compared to conventional, four-hour dialysis, according to research being presented at the American Society of Nephrology's 41st Annual Meeting and Scientific Exposition in Philadelphia, Pennsylvania.

8 Nov 2008

G Protein News and Research

Latest research on diagnosis and treatment of allergic diseases

Protein called TIM-3 turns off HIV-fighting T cells

Newborn neurons in the adult brain can settle in the wrong neighborhood

Simple blood test for high-sensitivity C-reactive protein is a useful marker for cardiovascular disease

Ewing sarcoma treatment ineffective, despite promising laboratory data

Santaris Pharma releases positive data on LNA-based survivin inhibitor

New risk factor for heart disease suggests more should be on statins

VIA Pharmaceuticals announces results of phase 2 trials of VIA-2291 in cardiovascular disease

T-cell-based strategy for HIV-1 vaccines still viable option

High levels of high-sensitivity C-reactive protein found to be new risk factor for cardiovascular disease

Five key proteins form new, early-warning blood test before heart attack strikes

Crestor (rosuvastatin calcium) shown to significantly reduce major cardiovascular events

Further evidence that angiogenesis drugs can be much more effective when combined with chemotherapy

Advances in ophthalmology

Sydney student solves piece of the diabetes puzzle

Overnight hemodialysis dramatically improves survival

Variations of MYH9 gene help explain high rate of kidney disease in African Americans

Acologix demonstrates improved bone architecture in rat model of chronic kidney disease

Research sheds light on possible role of DNA packaging in cancer development

The interaction between genes and behavior

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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