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NHCS researchers discover potential cure for long QT syndrome 2

The National Heart Centre Singapore research team has successfully and completely reversed the effects of the hERG (human ether-a-go-go-related gene) mutation in long QT syndrome 2 in patient-specific heart cells, scoring a world's first.

18 Sep 2013

Improve Your Lifestyle, Lengthen Your Telomeres

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17 Sep 2013

Findings underscore importance of communicating risks and benefits of CPM to women

Young women with breast cancer often overestimate the odds that cancer will occur in their other, healthy breast, and decide to have the healthy breast surgically removed, a survey conducted by Dana-Farber Cancer Institute investigators indicates.

17 Sep 2013

Flecainide, encainide drugs increase risk of sudden cardiac death

Scientists have discovered that a drug which increases the risk of sudden cardiac death interacts with mistranslated protein-coding genes present in heart muscle.

17 Sep 2013

Understanding essential role of gut microbes in immune system

A new understanding of the essential role of gut microbes in the immune system may hold the key to dealing with some of the more significant health problems facing people in the world today, Oregon State University researchers say in a new analysis.

17 Sep 2013

High exposure to swine manure in crop fields linked with increased risk of MRSA, soft-tissue infection

High exposure to swine manure spread in crop fields and proximity to high-density swine livestock operations appear to be associated with increased risk of methicillin-resistant Staphylococcus aureus (MRSA) and skin and soft-tissue infection in humans, according to a study published by JAMA Internal Medicine, a JAMA Network publication.

17 Sep 2013

Study shows that changes in diet, lifestyle choices may result in longer telomeres

A small pilot study shows for the first time that changes in diet, exercise, stress management and social support may result in longer telomeres, the parts of chromosomes that affect aging.

17 Sep 2013

Gentris expands genomic biomarker offering with launch of Affymetrix GeneChip HTA services

Gentris Corporation, a global leader in pharmacogenomics and biorepository solutions, announced today that it is expanding its genomic biomarker offering with the launch of Affymetrix GeneChip Human Transcriptome Array services.

17 Sep 2013

Researchers develop computational model to accurately simulate complex twists of RNA

A computational model developed by researchers at Rensselaer Polytechnic Institute is the first to accurately simulate the complex twists of a short sequence of RNA as it folds into a critical hairpin structure known as a "tetraloop."

17 Sep 2013

Researchers identify gene mutation linked to age-related macular degeneration

An international team of researchers, led by scientists at The Genome Institute at Washington University School of Medicine in St. Louis and the University of Michigan School of Public Health in Ann Arbor, has identified a gene mutation linked to age-related macular degeneration (AMD), the leading cause of blindness in Americans over age 50.

17 Sep 2013

Oxytocin shows evidence of therapeutic value for autism, schizophrenia

The hormone oxytocin could play a role in treating psychiatric disorders such as autism and schizophrenia, according to a review article in the September Harvard Review of Psychiatry. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

17 Sep 2013

Research: Immature sugar molecules aid growth properties of cancer cells

In co-operation with a research group from Singapore, scientists at University of Copenhagen have shown that immature sugar molecules in the form of truncated O-glycans aid growth properties of cancer cells.

17 Sep 2013

Researchers find that people affected by cold sores have mutation in gene

Why some people are troubled by cold sores while others are not has finally been explained by scientists. Cold sores affect around one in five people but, until now, no one has been sure why some are more prone to the virus that causes them.

17 Sep 2013

Gene panel predicts low-risk prostate cancer fate

Researchers from the USA have identified a three-gene signature that can predict prostate cancer progression in low Gleason score tumors.

16 Sep 2013

Gene variations predict breast cancer sleep disturbance

Researchers have identified cytokine gene variations in women with breast cancer that may help to identify those at increased risk for sleep disturbance following surgery.

16 Sep 2013

Studying Tumor Mutations Via A Network Approach

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16 Sep 2013

New approach subtypes cancers by shared genetic effects; a step toward personalized medicine

Cancer tumors almost never share the exact same genetic mutations, a fact that has confounded scientific efforts to better categorize cancer types and develop more targeted, effective treatments.

16 Sep 2013

Domestic animals less likely to be major source of antibiotic resistant Salmonella in humans

A new study has shown that, contrary to popular belief, local domestic animals are unlikely to be the major source of antibiotic resistant Salmonella in humans. The result comes from a detailed study of DNA from more than 370 Salmonella samples collected over a 22-year period.

13 Sep 2013

Scientists discover promising potential drug target for cystic fibrosis

Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg and Regensburg University, both in Germany, and the University of Lisboa, in Portugal, have discovered a promising potential drug target for cystic fibrosis.

13 Sep 2013

Researchers show network of genes which enforce cooperative state within cells

We often think of human cells as tiny computers that perform assigned tasks, where disease is a result of a malfunction. But in the current issue of Science, researchers at The Mount Sinai Medical Center offer a radical view of health — seeing it more as a cooperative state among cells, while they see disease as result of cells at war that fight with each other for domination.

13 Sep 2013