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New study reveals 'clutch' proteins responsible for putting T cell activation 'into gear'

In collaborative research, scientists from three continents were able to discover a crucial bit of information about how T cells move proteins inside them to drive the immune response. This could help evolve specific new treatments centered on T cell selectivity.

12 Jul 2019

Scripps CHAVD wins $129 million NIH grant to advance new HIV vaccine approach

The Scripps Consortium for HIV/AIDS Vaccine Development, an international collaboration led by Scripps Research, has received a $129 million grant from the National Institutes of Health to advance next-generation vaccines designed to coax the immune system into producing antibodies capable of disarming numerous strains of HIV.

11 Jul 2019

Finger-prick blood test could help prevent unnecessary antibiotic prescribing for patients with COPD

A simple finger-prick blood test could help prevent unnecessary prescribing of antibiotics for people with the lung condition chronic obstructive pulmonary disease, according to a new study by researchers from Cardiff University, University of Oxford and King's College London.

11 Jul 2019

Ancient epigenetic change deactivates some genes linked to cancer

An epigenetic change, a form of DNA control, that deactivates some genes linked to cancer late in human development has been conserved for more than 400 million years, new research led by the Garvan Institute of Medical Research suggests.

11 Jul 2019

Diet and physical exercise do not reduce risk of gestational diabetes

The assumption that minimizing weight gain in obese pregnant women is advantageous for avoiding gestational diabetes has not been borne out.

11 Jul 2019

New drug for acute migraine shows promising results in a large-scale trial

A drug belonging to a new generation of acute migraine headache treatments was found to eliminate pain and reduce bothersome symptoms for people with migraine in a large-scale trial reported in the July 11 issue of The New England Journal of Medicine.

11 Jul 2019

Comprehensive cell atlas of the human liver

The liver is one of the largest and most versatile organs of the human body. It turns sugars, proteins, and fats from our food into substances useful for the body and releases them to the cells.

11 Jul 2019

Researchers explain how 'viral' agents of neurological diseases ended up in our DNA

What if the missing ‘environmental’ factor in some of our deadliest neurological diseases were really written in our genome?

11 Jul 2019

Research reveals genetic cause of deadly digestive disease in children

Nearly 10 years ago, a group of Israeli clinical researchers emailed Lawrence Berkeley National Laboratory (Berkeley Lab) geneticist Len Pennacchio to ask for his team's help in solving the mystery of a rare inherited disease that caused extreme, and sometimes fatal, chronic diarrhea in children.

11 Jul 2019

Study highlights the need for larger Alzheimer's drug trials that intervene much earlier

There are currently no drugs that stop or inhibit Alzheimer's disease. Despite drug trials showing plaque reduction in the brain, the patients' cognitive function did not improve.

11 Jul 2019

Structure of bacteria responsible for traveler's diarrhea deciphered

For the first time researchers have deciphered the near-atomic structure of filaments, called 'pili', that extend from the surface of bacteria that cause traveler's diarrhea.

10 Jul 2019

Researchers report how a popular antidepressant drug could rewire the brain

Prozac, the trade name for the drug fluoxetine, was introduced to the U.S. market for the treatment of depression in 1988.

10 Jul 2019

Study could lead to new strategies for slowing the growth of glioblastoma

Researchers are hopeful that new strategies could emerge for slowing the growth and recurrence of the most common primary brain cancer in adults, glioblastoma, based on the results of a study published today in Cancer Research.

10 Jul 2019

New drug provides hope for patients with Duchenne muscular dystrophy

The results from three clinical trials have shown that a new drug can successfully delay the progression of Duchenne muscular dystrophy.

10 Jul 2019

UMD researchers connect a protein to antibody immunity for the first time

Human cytomegalovirus may not be a household name as far as viruses go, but according to Xiaoping Zhu, professor and chair in Veterinary Medicine at UMD, half of the population walking around campus is likely to be a carrier.

10 Jul 2019

UCR scientists decode genome of black-eyed peas

UC Riverside scientists have decoded the genome of black-eyed peas, offering hope for feeding Earth's expanding population, especially as the climate changes.

10 Jul 2019

Healthy high-fiber diet could reduce preeclampsia risk

A healthy diet rich in fiber is generally recommended, but new research shows it could be even more important during pregnancy to promote the wellbeing of the mother and child.

10 Jul 2019

Sorting protein in neurons protects against neurodegenerative disorders

Like a sorting machine in an assembly line, a molecule known as VPS35 detects and removes defective proteins from neurons.

10 Jul 2019

Hinge-like protein may unlock new pathways for cystic fibrosis treatment

In recent decades, treatment options for people with cystic fibrosis have improved dramatically. The newest drugs, known as potentiators, target a protein called cystic fibrosis transmembrane conductance regulator, which is mutated in people with the disease.

10 Jul 2019

UM scientists receive $3.3 million NIH contract to develop opioid addiction vaccine

The University of Montana has received a $3.3 million contract from the National Institutes of Health to develop an innovative vaccine targeting opioid addiction.

10 Jul 2019