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Hox genes control stem cells involved in forming and repairing bone

Genes long known to control the formation of bones before birth also control bone healing later in life, a new study found.

20 Mar 2023

Upgraded tumor model points the way toward more effective cancer therapies

Tumor cells won't show their true selves in a petri dish, isolated from other cells.

20 Mar 2023

Study finds higher levels of oral disease among patients with adverse mental health conditions

A study examining the mental health-oral health association cross-sectionally and longitudinally was presented at the 52nd Annual Meeting & Exhibition of the AADOCR, held in conjunction with the 47th Annual Meeting of the CADR.

20 Mar 2023

Scientists develop a marker for therapy response in acute myeloid leukemia

With the combination of the drugs Venetoclax and 5-Azacitidine, a new, effective and more tolerable alternative to chemotherapy for the treatment of AML has been available for several years. But for some patients, the drug combination does not work.

17 Mar 2023

Researchers fabricate first wearable sensor to detect and monitor muscle atrophy

Researchers at The Ohio State University have fabricated the first wearable sensor designed to detect and monitor muscle atrophy.

17 Mar 2023

How to assess clinical response in multiple myeloma

In this interview, Cerba Research explains how its teams were able to assess clinical response in multiple myeloma (MM) patients that were receiving monoclonal antibodies treatment,

From Cerba Research 16 Mar 2023

Scientists develop genetically defined mouse models for multiple myeloma subtypes

A team of scientists led by Martin Janz and Klaus Rajewsky at the Max Delbrück Center has successfully generated genetically defined mouse models for two subtypes of multiple myeloma.

16 Mar 2023

FDA looks into dental device after KHN-CBS news investigation of patient harm

In the wake of a joint investigation by KHN and CBS News into a dental appliance that multiple lawsuits allege caused grievous harm to patients, the FDA has begun looking into the product, the Anterior Growth Guidance Appliance, or AGGA, according to a former agency official.

15 Mar 2023

Hitchhiker plant's hooks inspire new suturing schemes for surgical reattachment of tendon to bone

For most people, getting burrs stuck to your clothes during a hike is nothing more than a nuisance, something to pick off and throw out when you get home.

14 Mar 2023

Bispecific antibody shows improved efficacy against SARS-CoV-2 variants

Researchers from The University of Texas MD Anderson Cancer Center have developed fully human bispecific antibodies, as revealed in a recent study. These antibodies can bind to two distinct epitopes of the receptor binding domain (RBD) of the SARS-CoV-2 spike protein and have demonstrated the ability to neutralize various strains of the virus, including the Omicron variant.

14 Mar 2023

UK HealthCare provides a symphony of support for doctoral student after rare stroke

On a Sunday afternoon in April, Adiel Nájera’s world turned upside down. The 25-year-old University of Kentucky doctoral student knew something was wrong. Earlier that week, he experienced exhaustion, chest pains and trouble driving.

10 Mar 2023

Scientists identify the cause of leukemia in people with trisomy 21

People with a third copy of chromosome 21, known as trisomy 21, are at high risk of developing Acute Myeloid Leukaemia (AML), an aggressive form of blood cancer.

10 Mar 2023

What is the effect of low Anti-Müllerian hormone on semen quality?

A recent BMC Medicine study investigated the relationship between Vitamin D and serum Anti-Müllerian hormone (AMH) in infertile men. This study was based on secondary analysis of a randomized clinical trial, which assessed the effect of high-dose Vitamin D plus calcium and placebo on semen quality in Vitamin D deficient infertile men.

10 Mar 2023

Study suggests a new approach for treating metastatic breast cancers

Metastatic breast cancer has no cure and has proven stubbornly resistant to one of the most innovative and promising new cancer treatments: immunotherapy.

8 Mar 2023

Detection and targeting of splicing deregulation reveal a potential strategy for pAML therapy

Pediatric acute myeloid leukemia or pAML is a childhood blood cancer, one that has proved confounding to clinicians and researchers, with a high relapse rate and relatively few identified genetic mutations (compared to the adult version) that might explain its cause.

8 Mar 2023

Novel culture system for effectively growing large numbers of blood stem cells in the lab

Hematopoietic stem cells (HSCs) are important immature blood cells in bone marrow that can be triggered to develop into any blood cell type.

8 Mar 2023

Breakthrough drug works against all the main types of primary bone cancer

Researchers at the University of East Anglia have developed a new drug that works against all of the main types of primary bone cancer.

8 Mar 2023

Newly identified bone matrix protein may help treat osteosarcoma

A study published in the Journal of Orthopaedic Research has identified a bone matrix protein called Secreted phosphoprotein 24 kD (Spp24) that may help to treat osteosarcoma, the most common type of bone cancer.

8 Mar 2023

Intermittent fasting's impact on bone health

Although several studies have indicated intermittent fasting (IF) promotes weight loss and improves metabolic health, its effect on bone health is unclear. Recently, scientists reviewed existing literature and summarized the effect of varied forms of IF, such as the 5:2 diet, alternate day fasting (ADF), and time-restricted eating/feeding (TRE/TRF), on bone health. This review is available in the British Journal of Nutrition.

7 Mar 2023

Research shows the benefits of screening AML patients in remission for residual disease before bone marrow transplant

Researchers at the National Institutes of Health show the benefits of screening adult patients in remission from acute myeloid leukemia (AML) for residual disease before receiving a bone marrow transplant.

7 Mar 2023

Bone News and Research

Hox genes control stem cells involved in forming and repairing bone

Upgraded tumor model points the way toward more effective cancer therapies

Study finds higher levels of oral disease among patients with adverse mental health conditions

Scientists develop a marker for therapy response in acute myeloid leukemia

Researchers fabricate first wearable sensor to detect and monitor muscle atrophy

How to assess clinical response in multiple myeloma

Scientists develop genetically defined mouse models for multiple myeloma subtypes

FDA looks into dental device after KHN-CBS news investigation of patient harm

Hitchhiker plant's hooks inspire new suturing schemes for surgical reattachment of tendon to bone

Bispecific antibody shows improved efficacy against SARS-CoV-2 variants

UK HealthCare provides a symphony of support for doctoral student after rare stroke

Scientists identify the cause of leukemia in people with trisomy 21

What is the effect of low Anti-Müllerian hormone on semen quality?

Study suggests a new approach for treating metastatic breast cancers

Detection and targeting of splicing deregulation reveal a potential strategy for pAML therapy

Novel culture system for effectively growing large numbers of blood stem cells in the lab

Breakthrough drug works against all the main types of primary bone cancer

Newly identified bone matrix protein may help treat osteosarcoma

Intermittent fasting's impact on bone health

Research shows the benefits of screening AML patients in remission for residual disease before bone marrow transplant

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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