High Throughput News and Research

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PBI announces receipt of first purchase order for new Barozyme HT48 High-throughput System

Pressure BioSciences, Inc., a leader in the development and sale of broadly enabling sample preparation solutions using pressure cycling technology ("PCT")-based instruments and consumables to the worldwide life sciences industry, today announced the receipt of the first purchase order for its new Barozyme HT48 High-throughput System.

10 Feb 2015

Study describes novel screening system that has potential to uncover effective ovarian cancer drugs

University of Chicago Medicine researchers have built a model system that uses multiple cell types from patients to rapidly test compounds that could block the early steps in ovarian cancer metastasis. Their three-dimensional cell-culture system, adapted for high-throughput screening, has enabled them to identify small molecules that can inhibit adhesion and invasion, preventing ovarian cancers from spreading to nearby tissues.

10 Feb 2015

Researchers develop quality assurance tool for genome editing

A research team at Boston Children's Hospital's Program in Cellular and Molecular Medicine has developed a quality assurance tool for scientists using genome-editing technologies like the increasingly popular CRISPR. The assay, called high throughput genome translocation sequencing (HTGTS), rapidly gauges—for any given gene—these technologies' accuracy and their risk for causing potentially dangerous genomic collateral damage.

9 Feb 2015

Gramicidin-Based Fluorescence Assay can help predict drug toxicity

Sometimes, toxic side effects aren't discovered until fairly late in the drug development process, when substantial amounts of time and money have already been invested in clinical trials.

9 Feb 2015

New RT-DC technology enables faster and continuous mechanical screening of cells

Cells, like any other material, have mechanical properties that can serve for their characterization. For example, cancer cells are characteristically more deformable than healthy cells.

9 Feb 2015

Genomics of papillary thyroid carcinoma (PTC): an interview with Professor Thomas J. Giordano

There are two types of thyroid cells and therefore there are two broad types of thyroid cancer. Medullary carcinoma is derived from parafollicular or C cells, whereas follicular cells give rise to several types of thyroid cancers.

4 Feb 2015

OGT study explores successful adoption of CytoSure ISCA array at Sheffield Children's NHS Foundation Trust

Oxford Gene Technology, The Molecular Genetics Company, explores how Sheffield Children's NHS Foundation Trust has seamlessly transferred to its CytoSure ISCA 8x60k platform, in a new case study entitled Evaluating and switching to CytoSure microarrays. As the result of a highly stringent National Health Service tender for the supply of oligo-based cytogenetics research arrays, CytoSure was selected based on the quality of data and analysis software.

From Oxford Gene Technology 4 Feb 2015

Productive Pipetting - Are Robots the Solution?

An interview with Juerg Bass from Integra Biosciences, discussing the advantages and disadvantages of laboratory robots.

From INTEGRA Biosciences 3 Feb 2015

TAU researchers identify novel proteins capable of stymieing growth in antibiotic-resistant bacteria

Antibiotic-resistant infections are on the rise, foiling efforts to reduce death rates in developing countries where uncontrolled use of antibiotics and poor sanitation run amok. The epidemic of "superbugs," bacteria resistant to antibiotics, knows no borders -- presenting a clear and present danger around the globe.

31 Jan 2015

Georgia Tech researchers unveil new version of genome annotation system

Georgia Tech researchers, working with colleagues in the National Center for Biotechnology Information, have released a new version of a genome annotation system capable of analyzing more than 2,000 prokaryotic genomes per day, helping researchers accelerate prokaryotic genomics-based studies worldwide.

27 Jan 2015

Biolin Scientific acquires the key patent protecting multi-hole, high-throughput ion channel screening

Biolin Scientific today announces the acquisition of a key patent related to performing multi-hole, high-throughput ion channel screening.

27 Jan 2015

Removing volatile organic solvents from your 96-well microplates in minutes

The MiniVap™ blowdown evaporator from Porvair Sciences takes just minutes to remove volatile organic solvents from your 96-well microplates. The MiniVap™ is the perfect tool for labs where smaller numbers of individual plates need drying.

From Chromatrap® - Porvair Sciences Ltd 26 Jan 2015

Penn researchers make breakthrough on novel anesthetics

Penn Medicine researchers, in a continuation of their groundbreaking work to better understand how anesthesia works in the body, have found the first new class of novel anesthetics since the 1970s. Their findings, published in February issue of Anesthesiology, detail the processes through which the group uncovered these compounds.

21 Jan 2015

Research opens door to potential new cancer biomarkers

A new analysis opens the door to discovery of thousands of potential new cancer biomarkers.

20 Jan 2015

Fast HPLC screening methods used to detect steroids

As the importance of steroids in the regulation of bioprocesses has increased so has the demand for fast screening methods for their detection. HPLC is a highly regarded analytical technique for pharmaceutical applications due to its unrivalled analytical validation characteristics; including accuracy, precision, limit of detection, specificity, linearity and range, and ruggedness.

16 Jan 2015

BellBrook Labs announces launch of new Transcreener UDP TR-FRET Assay

BellBrook Labs, a leader in high throughput screening assays for drug discovery, announced the launch of a TR-FRET (time resolved Forster resonance energy transfer) version of the company's Transcreener UDP Assay, a high throughput screening assay for glycosyltransferases and other UDP-producing enzymes.

15 Jan 2015

Beckman Coulter Life Sciences expands range of Avanti High Performance centrifuges

Beckman Coulter Life Sciences continues to expand its range of Avanti High Performance centrifuges with the launch of the Avanti JXN-30.

From Beckman Coulter Life Sciences - Centrifugation 13 Jan 2015

Porvair Sciences releases 2015 catalogue of tissue culture plastics and epigenetic consumables

Porvair Sciences has released a new 2015 catalogue that describes its popular range of high quality tissue culture treated plastics and consumable products for Epigenetics.

From Chromatrap® - Porvair Sciences Ltd 22 Dec 2014

UCLA researchers develop lens-free microscope that can detect cancer, other cell-level abnormalities

UCLA researchers have developed a lens-free microscope that can be used to detect the presence of cancer or other cell-level abnormalities with the same accuracy as larger and more expensive optical microscopes.

17 Dec 2014

Scientists suspect role of mini-chromosomes in cancers, diseases caused by gene mutations

Cancers are due to genetic aberrations in certain cells that gain the ability to divide indefinitely. This proliferation of sick cells generates tumors, which gradually invade healthy tissue. Therefore, current therapies essentially seek to destroy cancer cells to stop their proliferation. Through high-throughput genetic sequencing of glioblastoma cells, one of the most deadly brain tumors, a team of geneticists from the University of Geneva's (UNIGE) Faculty of Medicine discovered that some of these mutations are caused by supplemental extrachromosomal DNA fragments, called double minutes, which enable cancer cells to better adapt to their environment and therefore better resist to treatments meant to destroy them.

6 Dec 2014

High Throughput News and Research

PBI announces receipt of first purchase order for new Barozyme HT48 High-throughput System

Study describes novel screening system that has potential to uncover effective ovarian cancer drugs

Researchers develop quality assurance tool for genome editing

Gramicidin-Based Fluorescence Assay can help predict drug toxicity

New RT-DC technology enables faster and continuous mechanical screening of cells

Genomics of papillary thyroid carcinoma (PTC): an interview with Professor Thomas J. Giordano

OGT study explores successful adoption of CytoSure ISCA array at Sheffield Children's NHS Foundation Trust

Productive Pipetting - Are Robots the Solution?

TAU researchers identify novel proteins capable of stymieing growth in antibiotic-resistant bacteria

Georgia Tech researchers unveil new version of genome annotation system

Biolin Scientific acquires the key patent protecting multi-hole, high-throughput ion channel screening

Removing volatile organic solvents from your 96-well microplates in minutes

Penn researchers make breakthrough on novel anesthetics

Research opens door to potential new cancer biomarkers

Fast HPLC screening methods used to detect steroids

BellBrook Labs announces launch of new Transcreener UDP TR-FRET Assay

Beckman Coulter Life Sciences expands range of Avanti High Performance centrifuges

Porvair Sciences releases 2015 catalogue of tissue culture plastics and epigenetic consumables

UCLA researchers develop lens-free microscope that can detect cancer, other cell-level abnormalities

Scientists suspect role of mini-chromosomes in cancers, diseases caused by gene mutations

Industry Focus eBook - Life Science Microscopy (2nd Edition) eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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