Malignant News and Research

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Combination of high-intensity ultrasound and immunotherapy may be effective in treating cancer

In a new study published today in JCI Insight, UC Davis researchers have shown that combining high-intensity focused ultrasound with two immunotherapies (a PD-1 checkpoint inhibitor and TLR9 agonist) can produce excellent response rates in mouse models of epithelial cancer.

25 Mar 2017

Major grant funds research effort that seeks to understand complexity of invasive cancer

A $9.5 million, five-year grant from the National Cancer Institute (NCI) will fund an intensive multidisciplinary research effort that seeks to better understand how cancer cells reach an aggressive state and begin to damage surrounding tissue.

25 Mar 2017

New clinical approach offers hope for patients with aggressive brain cancer

Being diagnosed with a malignant brain tumor is devastating news for patients and their loved ones. Whereas some types of tumor respond well to treatment, others such as glioblastomas - the most common and aggressive brain tumors - are known to recur and progress within short times from the diagnosis.

23 Mar 2017

Many adults have poor knowledge about severity and prognosis of heart failure

In the largest German survey on heart failure to date, investigators found that the overall awareness of heart failure has not increased over the past decade and is not at a satisfactory level.

22 Mar 2017

Efficacy of innovative gene therapy can be tested quickly and cost-effectively using new cellular model

Using a new cellular model, innovative gene therapy approaches for the hereditary immunodeficiency Chronic Granulomatous Disease can be tested faster and cost-effectively in the lab for their efficacy.

21 Mar 2017

Study sheds light on cellular mechanisms that enable prostate cancer cells to form secondary tumours

New King's College London research sheds light on the cellular mechanisms which enable cancer cells to escape the prostate and spread to other parts of the body.

20 Mar 2017

Combination approach holds potential for treating lung cancer patients

An emerging approach for cancer treatment seeks to combine radiation therapy with immune checkpoint inhibitors to more effectively control tumors in the chest with an acceptable risk of severe treatment-related side effects.

17 Mar 2017

UT Southwestern researchers develop computer model to predict most deadly lung cancers

After evaluating more than 900 differences in the shape and structure of cancer cells, UT Southwestern Medical Center researchers developed a computer model able to predict the most deadly lung cancers based on a fraction of those features.

16 Mar 2017

Dietary anti-cancer compound from broccoli may work by influence on long non-coding RNAs

Researchers have discovered one of the reasons why broccoli may be good for your health.

16 Mar 2017

Study reveals mechanisms behind increased risk of thrombosis in patients with malignant brain tumours

Patients with malignant brain tumours have an increased risk of thrombosis. Up until now we did not understand the mechanisms behind this.

16 Mar 2017

Combined therapy extends survival of older patients with glioblastoma, clinical study shows

Treating older patients who have malignant brain cancer with the chemotherapy drug temozolomide plus a short course of radiation therapy extends survival by two months compared to treating with radiation alone, show clinical trial results published today in the New England Journal of Medicine.

15 Mar 2017

Antibody treats pediatric brain tumors safely and effectively in mice

Five types of pediatric brain cancer were safely and effectively treated in mice by an antibody that causes immune cells to engulf and eat tumors without hurting healthy brain cells, according to a new study by researchers at the Stanford University School of Medicine.

15 Mar 2017

New light-scattering tool helps doctors to accurately identify malignant pancreatic cysts

Pancreatic cancer has the lowest survival rate among all major cancers, largely because physicians lack diagnostic tools to detect the disease in its early, treatable stages.

13 Mar 2017

Seven facts about malignant hyperthermia that can help avoid dangerous consequences during surgery

When general anesthesia is required for surgery or another procedure, a patient's care team must be ready for anything—especially the rare, life-threatening syndrome known as malignant hyperthermia.

13 Mar 2017

Researchers identify new gene that can lead to sudden death among young people

Researchers from Canada, South Africa and Italy have identified a new gene that can lead to sudden death among young people and athletes.

10 Mar 2017

Researchers reveal potential health risks of deep space travel

Sending a manned mission to Mars requires more than a powerful launch rocket. Prep work also includes learning how a three-year space flight could affect the human body.

8 Mar 2017

Study reveals promising new strategy to attack deadly pediatric brain tumor

Researchers from Northwestern Medicine and Ann & Robert H. Lurie Children's Hospital of Chicago have revealed new insight into how the most deadly pediatric brain tumor, diffuse intrinsic pontine glioma (DIPG), may develop.

7 Mar 2017

Research findings could guide development of potent combination therapies for leukemia

New findings from Rockefeller University researchers could guide the development of potent combination therapies that deliver more effective and durable treatment of leukemia.

7 Mar 2017

Two migration proteins increase predictive ability of biomarker for pancreatic cancer

Adding two blood-borne proteins associated with cancer cell migration increases the predictive ability of the current biomarker for pancreatic cancer to detect early stage disease, a research team from The University of Texas MD Anderson Cancer Center reports in the Journal of the National Cancer Institute.

1 Mar 2017

Danish researchers get closer to finding treatment for malignant cerebral tumour in children

DIPG (Diffuse Intrinsic Pontine Glioma) is a rare malignant cerebral tumour in children. It has only a 1% 5-year survival rate, amongst other things because it is not possible to operate because the tumour is located in the brain stem.

28 Feb 2017

Malignant News and Research

Combination of high-intensity ultrasound and immunotherapy may be effective in treating cancer

Major grant funds research effort that seeks to understand complexity of invasive cancer

New clinical approach offers hope for patients with aggressive brain cancer

Many adults have poor knowledge about severity and prognosis of heart failure

Efficacy of innovative gene therapy can be tested quickly and cost-effectively using new cellular model

Study sheds light on cellular mechanisms that enable prostate cancer cells to form secondary tumours

Combination approach holds potential for treating lung cancer patients

UT Southwestern researchers develop computer model to predict most deadly lung cancers

Dietary anti-cancer compound from broccoli may work by influence on long non-coding RNAs

Study reveals mechanisms behind increased risk of thrombosis in patients with malignant brain tumours

Combined therapy extends survival of older patients with glioblastoma, clinical study shows

Antibody treats pediatric brain tumors safely and effectively in mice

New light-scattering tool helps doctors to accurately identify malignant pancreatic cysts

Seven facts about malignant hyperthermia that can help avoid dangerous consequences during surgery

Researchers identify new gene that can lead to sudden death among young people

Researchers reveal potential health risks of deep space travel

Study reveals promising new strategy to attack deadly pediatric brain tumor

Research findings could guide development of potent combination therapies for leukemia

Two migration proteins increase predictive ability of biomarker for pancreatic cancer

Danish researchers get closer to finding treatment for malignant cerebral tumour in children

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