in vitro News and Research

RSS

World's first-in-human research using organoid transplantation yields good results

Tokyo Medical and Dental University (TMDU) research team announced on July 7 that it has succeeded in the world's first clinical transplantation of a "mini organ (also called Organoid)" into a patient with "Ulcerative Colitis (UC)".

22 Aug 2022

Researchers discover how patients with mutations in a DNA sequence develop pancreatic malformations

Researchers at the Centre for Genomic Regulation have identified a DNA sequence that is crucial for pancreatic differentiation and function – and for the first time – describe how it works.

22 Aug 2022

The effectiveness of three repurposed drugs in preventing serious SARS-CoV-2 infection in non-hospitalized adults

Researchers conducted a phase III clinical trial to test the effectiveness of three repurposed drugs - metformin, ivermectin, and fluvoxamine, in preventing progression to severe COVID-19.

22 Aug 2022

Celebrating 10 Years of Global Research with Breast Cancer Now Tissue Bank

Breast Cancer Now Tissue Bank have just celebrated 10 years of groundbreaking breast cancer research. We spoke to Professor Louise Jones to find out more about this achievement!

22 Aug 2022

Re-defining the limits of single batch assay stabilisation

In response to increasing demand for stabilised molecular diagnostic assays, we have significantly increased our single batch lyophilised reagent bead manufacturing throughput to 300,000 reactions per freeze drying run and are now progressing towards a capacity of 100 million tests per annum.

From Biofortuna Limited 22 Aug 2022

Single dose of aged mouse blood in young mice causes senescence

Scientists performed heterochronic blood exchange in male mice and observe that aged mouse blood triggered cell and tissue senescence in younger mice.

18 Aug 2022

CD98 identified as a key mediator of pro-fibrotic and acute inflammatory responses in the lung

Researchers investigated the role of the CD98 glycoprotein in inducing an inflammatory response to SARS-CoV-2 in patients of progressive fibrosis interstitial lung diseases, including the archetypal PFILD, idiopathic pulmonary fibrosis.

18 Aug 2022

Novel same-day test developed to identify extra or missing fetal chromosomes

Scientists funded by the National Institutes of Health have developed a same-day test to identify abnormal fetal chromosomes.

17 Aug 2022

Inventia Life Science partners with Xylyx Bio to develop tissue-specific, digitally-printed bioinks for drug discovery

Inventia Life Science and Xylyx Bio today announced their strategic partnership following promising results developing more realistic, scalable, and reproducible 3D cell cultures for drug discovery and biomedical research.

From Inventia Life Science 16 Aug 2022

Inventia Life Science and BioLamina partner to advance cell matrices for complex 3D cell models

As a result of this partnership, Inventia Life Science will now offer BioLamina’s extensive range of Biolaminin® products incorporated into the pre-validated library of RASTRUM™ Matrices, recapitulating the key motifs found in the native tissue of various cell types.

From Inventia Life Science 16 Aug 2022

Mechanism of vaccinia virus assembly in infected-cells

In a new study, researchers explored the driving factors of the vaccinia virus assembly across infected cells.

16 Aug 2022

What is the potential role of sphingosine kinase inhibitors as antiviral agents?

In a new study, researchers explored sphingosine kinases inhibitors and characterized the role of SKs in Ebola virus (EBOV) entry.

16 Aug 2022

Study offers more quantitative insights into long-term health risks of thirdhand smoke exposure

Some smells seem to seep into everything they touch. Tobacco smoke is one of the worst offenders.

15 Aug 2022

Study shows astrocytes as breeding grounds of SARS-CoV-2 during brain infection

Researchers evidenced the presence of SARS-CoV-2 in the human brain, infecting astrocytes and impairing neuronal function and viability.

15 Aug 2022

Study identifies multiple pathways adopted by SARS-CoV-2 to develop resistance to nirmatrelvir

Researchers demonstrated multiple routes SARS-CoV-2 might take to develop high-level resistance to nirmatrelvir, an oral antiviral targeting the 3C-like protease (3CLpro) of SARS-CoV-2.

11 Aug 2022

SARS-CoV-2 receptor-binding domain-based protein subunit vaccine shows promise against multiple SARS-CoV-2 variants

Researchers described a novel protein subunit vaccine comprising the receptor-binding domain (RBD) of ancestral SARS-CoV-2 spike (S) protein, dimerized with an immunoglobulin (Ig)G1-fraction, crystallizable (Fc) domain.

11 Aug 2022

New computation-guided approach to identify small molecule corrector drugs for p53 hotspot mutations

A new study, led by researchers from the University of California, Irvine and the University of California, San Diego, reveals a new computation-guided approach to identify small molecules that can restore aspects of wild-type p53 tumor suppression function to mutated p53, which play an important role in many human cancers.

11 Aug 2022

in vitro News and Research

World's first-in-human research using organoid transplantation yields good results

Researchers discover how patients with mutations in a DNA sequence develop pancreatic malformations

The effectiveness of three repurposed drugs in preventing serious SARS-CoV-2 infection in non-hospitalized adults

Celebrating 10 Years of Global Research with Breast Cancer Now Tissue Bank

Re-defining the limits of single batch assay stabilisation

Single dose of aged mouse blood in young mice causes senescence

CD98 identified as a key mediator of pro-fibrotic and acute inflammatory responses in the lung

Novel same-day test developed to identify extra or missing fetal chromosomes

Inventia Life Science partners with Xylyx Bio to develop tissue-specific, digitally-printed bioinks for drug discovery

Inventia Life Science and BioLamina partner to advance cell matrices for complex 3D cell models

Mechanism of vaccinia virus assembly in infected-cells

What is the potential role of sphingosine kinase inhibitors as antiviral agents?

Study offers more quantitative insights into long-term health risks of thirdhand smoke exposure

Study shows astrocytes as breeding grounds of SARS-CoV-2 during brain infection

Study identifies multiple pathways adopted by SARS-CoV-2 to develop resistance to nirmatrelvir

SARS-CoV-2 receptor-binding domain-based protein subunit vaccine shows promise against multiple SARS-CoV-2 variants

New computation-guided approach to identify small molecule corrector drugs for p53 hotspot mutations

Review of natural products with promising anti-SARS-CoV-2 potential

The features of the newly emerging SARS-CoV-2 Omicron BA.2.75 subvariant

A direct lineage-typing RT-PCR assay reveals insights into the transition from Omicron BA.1 to BA.2 dominance in Sweden

eBook: Using iPSCs models for human disease research and drug discovery eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Latest News