Protein C News and Research

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Researchers synthesize artificial cells to detect histamine

Baking a cake from scratch is a task deemed difficult for many. Constructing an artificial cell-like system from scratch, well that's another story.

3 Jul 2019

New resistance mechanism that prevent formation of blood vessels

Researchers at IDIBELL-ICO describe a new resistance mechanism to therapies that prevent the formation of blood vessels

3 Jul 2019

Using popular anticonvulsant drug to thwart inflammation

Serious conditions, including sepsis, stem from inflammation in the body, and there is a lack of effective medication for sepsis.

2 Jul 2019

Copper compound with potential as therapy for ALS shows further promise

A compound with potential as a treatment for ALS has gained further promise in a new study that showed it improved the condition of mice whose motor neurons had been damaged by an environmental toxin known to cause features of ALS.

2 Jul 2019

Gene mutations may not always predict cardiomyopathy

More than 750,000 people in the United States have dilated cardiomyopathy, a potentially life-threatening condition in which the heart's main pumping chamber, the left ventricle, enlarges and grows increasingly weak.

2 Jul 2019

'Scissors' component of CRISPR/Cas9 sometimes gets stuck

In biotech these days, CRISPR/Cas9 is a hot topic, because of its utility as a precise gene editing tool. Before humans repurposed it, CRISPR/Cas9 was a sort of internal immune system bacteria use to defend themselves against phages, or viruses that infect bacteria, by slicing up the phages' DNA.

2 Jul 2019

Georgia State researcher wins $3.26 million federal grant to develop universal flu vaccine

Influenza remains a major public health risk, and Dr. Baozhong Wang, associate professor in Georgia State University's Institute for Biomedical Sciences, has received a five-year, $3.26 million federal grant to combat this threat by developing a universal vaccine that offers more protection against influenza than seasonal vaccines.

2 Jul 2019

Novel imaging molecule reveals brain changes linked to progressive MS

Secondary progressive multiple sclerosis is a relentless disease. Over time, patients experience worsening physical, mental and mood-related symptoms.

2 Jul 2019

Discovery by NETRF-funded researchers may help predict recurrence of pNETs

ARX and PDX1 levels can be measured using immunohistochemistry, a test that stains tumor tissue and is routine in clinical laboratories.

2 Jul 2019

Scientists identify new genetic mutation behind serious skull disorder

A collaboration led by scientists at Oregon State University, the University of Oxford in the United Kingdom and Erasmus University in The Netherlands has identified a new genetic mutation behind the premature fusing of the bony plates that make up the skull.

2 Jul 2019

Gene mutation discovery leads to novel treatment for patient with severe lymphatic condition

Faced with a preteen boy in pain and struggling to breathe from a severe, deteriorating rare condition, researchers at Children's Hospital of Philadelphia identified the responsible gene mutation and harnessed that knowledge to develop a novel treatment that dramatically improved the problem.

2 Jul 2019

Rutgers-led study sheds light on the origins of metabolism

A Rutgers-led study sheds light on one of the most enduring mysteries of science: How did metabolism – the process by which life powers itself, by converting energy from food into movement and growth – begin?

2 Jul 2019

Researchers determine atomic interactions that stabilize phase-changing proteins

Most of the well-studied proteins in our bodies are like metal; some can change shape easily, like aluminum foil, and others are rigid, like steel beams, but they typically have a solid, well-defined structure.

2 Jul 2019

Protein Clumps In ALS Neurons Provide Potential Target For New Therapies

Amyotrophic lateral sclerosis is a neurological condition that affects motor neurons -- the nerve cells that control breathing and muscles.

2 Jul 2019

Promising method delivers drug to cancer cells without affecting surrounding cells

RIKEN researchers have developed a promising method to deliver a drug to cancer cells without affecting surrounding tissues, involving a clever combination of an "artificial metalloenzyme" that protects a metal catalyst, and a sugar chain that guides the metalloenzyme to the desired cells.

2 Jul 2019

Scientists uncover new pathway to make cancers self-destruct

For years, researchers have been trying to target a gene called MYC that is known to drive tumor growth in multiple cancer types when it is mutated or over-expressed, but hitting that target successfully has proven difficult.

1 Jul 2019

$3.1 million NIH funding awarded to develop universal flu vaccine

In the race to create a universal flu vaccine not dependent on predicting strains of flu, the Virginia-Maryland College of Veterinary Medicine's Department of Veterinary Medicine at the University of Maryland College of Agriculture and Natural Resources has been awarded a $3.1 million grant.

1 Jul 2019

Digital campaign aims to raise awareness about potential severity of rare condition PKU

For the first time, patient groups, supported by funding from BioMarin, from six countries in Europe have come together with the shared goal of improving health services for people living with the rare condition PKU as part of the Live Unlimited PKU campaign.

1 Jul 2019

Research provides genomic warning flag just in time for beach season

An article published today in the Open Access journal GigaScience might make you squirm if you plan to hit the beach this summer. The article presents the draft genomes of three different jellyfish species.

30 Jun 2019

Scientists unravel how cells unfold proteins

A happy cell is a balanced cell, but for every stupendously twisted protein it creates, it must tear the old ones asunder. That means untangling a convoluted pretzel-like mass for recycling. Cdc48 plays a critical role in unraveling the spent proteins.

29 Jun 2019