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FDA seeks order of permanent injunction to stop two stem cell clinics from marketing stem cell products

The U.S. Food and Drug Administration, in two complaints filed today in federal court, is seeking permanent injunctions to stop two stem cell clinics from marketing stem cell products without FDA approval and for significant deviations from current good manufacturing practice requirements.

10 May 2018

Penn engineers develop faster way to make drug microparticles

Pharmaceuticals owe their effects mostly to their chemical composition, but the packaging of these drugs into specific physical formulations also need to be done to exact specifications.

9 May 2018

Johns Hopkins researchers identify protein clumps in diseased hearts

Similar to how protein clumps build up in the brain in people with some neurodegenerative diseases such as Alzheimer's and Parkinson's diseases, protein clumps appear to accumulate in the diseased hearts of mice and people with heart failure, according to a team led by Johns Hopkins University researchers.

9 May 2018

Giving identical subsidies can get gold-standard medications into the hands of consumers

Equal subsidies "surprisingly powerful," in promoting use of gold-standard medications, new study shows.

9 May 2018

Newly developed technique allows researchers to study liver stage malaria

A newly developed technique allows researchers to more easily study malaria outside the human body during the earliest point of infection, the liver.

9 May 2018

STEM workshop highlights the need to impart advanced training and education on clean, sustainable pharmaceutical manufacturing

DSM Sinochem Pharmaceuticals, global leader in sustainable antibiotics, in collaboration with the Indian Institute of Technology, New Delhi organized a workshop today on 'Sustainability through Excellence in Manufacturing (STEM)' to impart advanced training and education to industry stakeholders on high quality, clean and sustainable pharmaceutical manufacturing.

9 May 2018

Research findings could lead to new therapies to curb ovarian cancer metastasis

In order to spread their destruction, ovarian cancer cells must break free from their tumor home, travel through the fluid in the peritoneal cavity and attach to the outside of the abdominal organs--surfaces that are, by necessity, not sticky.

9 May 2018

Scientists develop computer algorithm that reveals gene networks activated in cancer cell

Recent headlines have cast suspicion on social network analysis, which can mine data from the internet to target advertisements or potentially influence elections.

9 May 2018

Flushing the bladder with common chemotherapy drug after surgery can reduce bladder cancer recurrence

Flushing the bladder with a common chemotherapy drug immediately after surgery significantly reduces the chances of bladder cancer returning, according to a major study by SWOG, an international clinical trials network funded by the National Cancer Institute.

9 May 2018

Researchers uncover the cause of scarring in idiopathic pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is one of the most challenging and frustrating diseases that pulmonologists face.

9 May 2018

New findings point to potential therapeutic avenues for leukemia

Scientists have known for decades that the Hox family of transcription factors are key regulators in the formation of blood cells and the development of leukemia.

9 May 2018

Baldness treatment using a medication for osteoporosis

According to researchers, a drug used to treat patients with osteoporosis may soon be helpful in treating baldness. The study was published in the latest issue of the journal PLOS Biology this week.

9 May 2018

Invasive surgery should be done for select patients with acid reflux, says study

As the number of Americans with acid reflux grows, a study by researchers at the University of Colorado Anschutz Medical Campus says invasive procedures to treat those who don't respond to medication should be done for select patients.

8 May 2018

Scientists discover how potential new drug targets spinal muscular atrophy

Spinal muscular atrophy (SMA) is a genetic disease that can leave infants with weak muscles and trouble breathing. Many with the disease die before age two. To help these patients, doctors need therapies that target the genetic mutation and stop its progression.

8 May 2018

Neon Therapeutics evaluates safety, efficacy of NEO-PV-01 in combination with KEYTRUDA and chemotherapy

Neon Therapeutics, a clinical-stage immuno-oncology company developing neoantigen-based therapeutics, today announced that it has treated the first patient in a clinical trial evaluating its proprietary personal neoantigen vaccine, NEO-PV-01, in combination with Merck's anti-PD-1 therapy, KEYTRUDA®, along with chemotherapy.

8 May 2018

How the farm bill could erode part of the ACA

Some Republican lawmakers continue to try to work around the federal health law's requirements. That strategy can crop up in surprising places. Like the farm bill.

8 May 2018

PFKFB3 enzyme appears to play a key role in pulmonary hypertension

A new and early target for treating pulmonary hypertension appears to be an enzyme that's normally key to energy production but destructive in the face of this high blood pressure inside your lungs.

8 May 2018

Use of psychiatric drugs soars in California jails

The number of jail inmates in California taking psychotropic drugs has jumped about 25 percent in five years, and they now account for about a fifth of the county jail population across the state, according to a new analysis of state data.

8 May 2018

Medicare beneficiaries feel the pinch when they can’t use drug coupons

This week, I answered a grab bag of questions about drug copay coupons and primary care coverage on the health insurance marketplace.

8 May 2018

FDA grants approval for two drugs administered together to treat aggressive form of thyroid cancer

The U.S. Food and Drug Administration approved Tafinlar (dabrafenib) and Mekinist (trametinib), administered together, for the treatment of anaplastic thyroid cancer (ATC) that cannot be removed by surgery or has spread to other parts of the body (metastatic), and has a type of abnormal gene, BRAF V600E (BRAF V600E mutation-positive).

8 May 2018

Drugs News and Research

FDA seeks order of permanent injunction to stop two stem cell clinics from marketing stem cell products

Penn engineers develop faster way to make drug microparticles

Johns Hopkins researchers identify protein clumps in diseased hearts

Giving identical subsidies can get gold-standard medications into the hands of consumers

Newly developed technique allows researchers to study liver stage malaria

STEM workshop highlights the need to impart advanced training and education on clean, sustainable pharmaceutical manufacturing

Research findings could lead to new therapies to curb ovarian cancer metastasis

Scientists develop computer algorithm that reveals gene networks activated in cancer cell

Flushing the bladder with common chemotherapy drug after surgery can reduce bladder cancer recurrence

Researchers uncover the cause of scarring in idiopathic pulmonary fibrosis

New findings point to potential therapeutic avenues for leukemia

Baldness treatment using a medication for osteoporosis

Invasive surgery should be done for select patients with acid reflux, says study

Scientists discover how potential new drug targets spinal muscular atrophy

Neon Therapeutics evaluates safety, efficacy of NEO-PV-01 in combination with KEYTRUDA and chemotherapy

How the farm bill could erode part of the ACA

PFKFB3 enzyme appears to play a key role in pulmonary hypertension

Use of psychiatric drugs soars in California jails

Medicare beneficiaries feel the pinch when they can’t use drug coupons

FDA grants approval for two drugs administered together to treat aggressive form of thyroid cancer

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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