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Study uncovers new genetic markers linked to testicular germ cell tumors

Testicular cancer is relatively rare with only 8,850 cases expected this year in the United States. A majority of testicular cancer, 95 percent of all cases, begins in testicular germ cells, which are the cells responsible for producing sperm.

13 Jun 2017

Genetic testing getting better at identifying testicular cancer risk

Testing for a new group of genes associated with testicular cancer has improved the ability to identify men at greatest risk of the disease, say researchers. Scientists at The Institute of Cancer Research, London, found that by testing for 19 new genetic factors in addition to the 25 risk genes already known, they could identify the 1% of men at highest risk.

13 Jun 2017

Dietary practices get reflected in the genes of Europeans, study reveals

A recently published Cornell University study describes how shifts in the diets of Europeans after the introduction of farming 10,000 years ago led to genetic adaptations that favored the dietary trends of the time.

13 Jun 2017

Low levels of vitamin A could be strong risk factor for TB

People with low levels of vitamin A living with individuals sick with tuberculosis may be 10 times more likely to develop the disease than people with high levels of the nutrient, according to research led by investigators at Harvard Medical School.

13 Jun 2017

Review suggests need for improved treatment outcome measures in clinical trials for FXS

A group of researchers from several institutions in the USA, including Johns Hopkins Medicine, reports that its review of 22 clinical trials of fragile X syndrome (FXS) suggests the need for a wider use of newer and improved treatment outcome measurement tools for this and other several neurodevelopmental disorders.

13 Jun 2017

Penn analysis finds genetic factors that could help identify men at increased risk for testicular cancer

An analysis of data from five major studies of testicular cancer has identified new genetic locations that could be susceptible to inherited testicular germ cell tumors.

12 Jun 2017

Exposure to carcinogenic compounds can come with inhalation of vaporized cannabis oil, study shows

New research shows that the agents commonly mixed with cannabis oil for vaping can also produce cancer-causing compounds when heated.

12 Jun 2017

Study reveals role of mast cells in severe forms of dengue infection

Why mosquito-borne dengue virus causes more severe disease in some individuals, including hemorrhagic fever with or without shock, remains controversial and researchers are focusing on the factors related to the interaction between the virus and the host immune system, including the role of mast cells.

12 Jun 2017

UC scientists use artificial intelligence to accurately predict treatment outcomes for bipolar disorder

The artificial intelligence that can blow human pilots out of the sky in air-to-air combat accurately predicted treatment outcomes for bipolar disorder, according to a new medical study by the University of Cincinnati.

12 Jun 2017

Researchers uncover seven risk genes for insomnia

An international team of researchers has found, for the first time, seven risk genes for insomnia. With this finding the researchers have taken an important step towards the unraveling of the biological mechanisms that cause insomnia.

12 Jun 2017

Decades-old drug used to treat malaria reduces toxic protein linked to ALS

A new study finds that a decades-old drug used to treat malaria lowers levels of a biomarker linked to the inherited form of amyotrophic lateral sclerosis, also known as ALS and Lou Gehrig's Disease.

12 Jun 2017

Emerging blood test could offer effective alternative to detect cancer

Research into a blood test that may spot cancers sooner and allow more targeted treatment is to be presented by a University of Leicester researcher.

12 Jun 2017

Anorexia nervosa linked to genetic anomalies on chromosome 12

A large-scale, international whole-genome analysis has now revealed for the first time that anorexia nervosa is associated with genetic anomalies on chromosome 12.

12 Jun 2017

KAUST-led researchers reveal epigenetic mechanism for gene regulation

An epigenetic mechanism regulating gene activity has been revealed by a KAUST-led international team of researchers investigating interactions between the human genome and its environment in adult tissues.

12 Jun 2017

'Mismatch repair' genetic defects drive cancer patient's response to immunotherapy drugs

In an expanded, three-year clinical trial of 86 patients with colorectal and 11 other kinds of cancer that have so-called 'mismatch repair' genetic defects, scientists at Johns Hopkins Medicine and its Bloomberg~Kimmel Institute for Cancer Immunotherapy have found that half of the patients respond to an immunotherapy drug called pembrolizumab.

9 Jun 2017

Joslin Diabetes Center researchers establish CCTD to develop and translate cell-based interventions

Researchers and clinicians at Joslin Diabetes Center have established a Center for Cell-Based Therapy for Diabetes, the goal of which is to lead the development and translation of cell-based interventions to treat and cure diabetes and its complications.

9 Jun 2017