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Study: Fenofibrate not a useful strategy for decreasing COVID-19 severity

After showing promise in early laboratory research, the cholesterol-lowering drug fenofibrate had no significant effect on COVID-19 outcomes in a multicenter international randomized clinical trial led by Penn Medicine scientists.

8 Nov 2022

Restoring blood flow to the legs reduces pain, improves quality of life for people with peripheral artery disease

Restoring blood flow to the legs, whether through bypass surgery or a less invasive artery-opening procedure with a stent, reduced pain and improved quality of life for people with peripheral artery disease (PAD), according to preliminary, late-breaking research presented today at the American Heart Association's Scientific Sessions 2022.

7 Nov 2022

Long-term administration of IV iron benefits adults with heart failure and iron deficiency

Long-term treatment with iron administered intravenously improved symptoms and reduced recurrent hospitalizations among people with heart failure and iron deficiency, according to late-breaking research presented today at the American Heart Association's Scientific Sessions 2022.

7 Nov 2022

Mindfulness may offer a novel way to improve blood pressure control

A customized mindfulness program that taught participants to apply those skills to have healthy relationships with their diet, physical activity, alcohol use, medication adherence and stress, led to notably lower systolic (top number) blood pressure measures six months after participating in the mindfulness program, according to late-breaking science presented today at the American Heart Association's Scientific Sessions 2022.

7 Nov 2022

Administering steroids during heart surgery does not improve post-operative outcomes in infants

The largest clinical trial ever conducted in infants younger than age 1 undergoing heart surgery with cardiopulmonary bypass found that administering steroids during surgery did not improve post-operative outcomes compared to placebo, according to preliminary late-breaking research to be presented at the American Heart Association's Scientific Sessions 2022.

7 Nov 2022

Bypass surgery linked to fewer amputations in people with severe peripheral artery disease

People with severe peripheral artery disease, or PAD, who received bypass surgery to improve blood flow to their legs and feet had 65 percent fewer repeat procedures and 27% fewer amputations than those who had minimally invasive procedures such as angioplasty and stenting, according to preliminary late-breaking research presented today at the American Heart Association's Scientific Sessions 2022.

7 Nov 2022

Early use of ECMO devices to support adults with cardiogenic shock did not improve clinical outcomes

The immediate use of veno-arterial mechanical circulatory extracorporeal membrane oxygenation (ECMO) devices to support adults with rapidly deteriorating or severe cardiogenic shock was feasible but did not improve clinical outcomes compared to people who received early conservative therapy, according to late-breaking clinical trial results presented today at the American Heart Association's Scientific Sessions 2022.

7 Nov 2022

SGLT-2 inhibitors reduce cardiovascular risk among patients with chronic kidney disease

SGLT-2 inhibitors, a type of diabetes medicine, decreased cardiovascular risk among adults with chronic kidney disease, according to late-breaking research presented today at the American Heart Association's Scientific Sessions 2022.

7 Nov 2022

Dietary supplements taken for 'heart health' unlikely to offer meaningful impact on cholesterol levels

Six widely used dietary supplements promoted for improving heart health did not effectively lower LDL or "bad" cholesterol in comparison to a common low-dose statin medication or placebo, according to late breaking science results presented today at the American Heart Association's Scientific Sessions 2022.

7 Nov 2022

Novel gene editing therapy reduces circulating TTR protein levels in patients with ATTR amyloid cardiomyopathy

A single IV infusion of NTLA-2001, a novel CRISPR/Cas9-based gene editing therapy, significantly reduced circulating transthyretin (TTR) protein levels in patients with ATTR amyloid cardiomyopathy, a progressive and fatal cause of heart failure, according to late-breaking research presented today at the American Heart Association’s Scientific Sessions 2022.

7 Nov 2022

New medication lowers triglyceride levels, yet does not decrease cardiovascular risk in people with Type 2 diabetes

A new medication, pemafibrate, lowered triglyceride levels among adults with Type 2 diabetes yet did not decrease their cardiovascular risk, according to late-breaking science research presented today at the American Heart Association's Scientific Sessions 2022.

7 Nov 2022

National study sheds light on how to more effectively treat atrial fibrillation

A national study led by UBC researchers at the Centre for Cardiovascular Innovation is shedding light on how to more effectively treat atrial fibrillation (AF) – a common heart rhythm problem associated with increased risk of stroke and heart failure.

7 Nov 2022

Personalized 'precision' testing approach leads to efficient chest pain evaluations for heart disease risk

For people with stable chest pain, a personalized "precision" testing approach led to more efficient evaluations for heart disease risk and improved diagnosis and treatment of coronary artery disease when compared to usual care, according to late-breaking science presented today at the American Heart Association's Scientific Sessions 2022.

7 Nov 2022

New ‘guard rails’ could significantly bolster high quality care using telehealth

Today's telemedicine providers are only scratching the surface of what's possible in providing high-quality healthcare to people who need it most - and especially to older adults who benefit greatly from its accessibility, according to researchers and clinical experts from West Health.

7 Nov 2022

LSU Health New Orleans to receive patent for a noninvasive test to diagnose fatal condition in preemies

US Patent 11,493,515 will be issued to LSU Health New Orleans on November 8, 2022, for a noninvasive test that more accurately diagnoses a potentially fatal condition in premature infants.

7 Nov 2022

High-intensity treatment strategy for heart failure reduces the risk of death or hospital readmission

Ramping up medication doses quickly after being hospitalized for acute heart failure resulted in a lower risk of dying or being readmitted for heart failure within the first six months after discharge, compared to usual care, according to a featured science research presentation today at the American Heart Association's Scientific Sessions 2022.

7 Nov 2022

Medicine News and Research

Study: Fenofibrate not a useful strategy for decreasing COVID-19 severity

Restoring blood flow to the legs reduces pain, improves quality of life for people with peripheral artery disease

Long-term administration of IV iron benefits adults with heart failure and iron deficiency

Mindfulness may offer a novel way to improve blood pressure control

Administering steroids during heart surgery does not improve post-operative outcomes in infants

Bypass surgery linked to fewer amputations in people with severe peripheral artery disease

Early use of ECMO devices to support adults with cardiogenic shock did not improve clinical outcomes

SGLT-2 inhibitors reduce cardiovascular risk among patients with chronic kidney disease

Dietary supplements taken for 'heart health' unlikely to offer meaningful impact on cholesterol levels

Novel gene editing therapy reduces circulating TTR protein levels in patients with ATTR amyloid cardiomyopathy

New medication lowers triglyceride levels, yet does not decrease cardiovascular risk in people with Type 2 diabetes

National study sheds light on how to more effectively treat atrial fibrillation

Personalized 'precision' testing approach leads to efficient chest pain evaluations for heart disease risk

New ‘guard rails’ could significantly bolster high quality care using telehealth

LSU Health New Orleans to receive patent for a noninvasive test to diagnose fatal condition in preemies

High-intensity treatment strategy for heart failure reduces the risk of death or hospital readmission

Combining chemotherapy with an inflammation inhibitor can prevent breast cancer metastasis

ACR releases new guideline that offers recommendations for integrative approach to RA treatment

Study reveals the extent of aggression towards caregivers in Parkinson's disease

UC San Diego Health earns The Joint Commission’s Gold Seal of Approval for Advanced Certification in Spine Surgery

Everything there is to know about biosimilars eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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