Protein C News and Research

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Researchers provide insight into unintended consequence of immune checkpoint inhibitors

Immune checkpoint inhibitors are an emerging type of cancer immunotherapy that uses the immune system to attack cancer cells.

12 Jun 2019

New therapeutic approach utilizes endogenous processes to enhance cardiac repair

Myocardial infarction results in the localized death of the muscle cells that are essential for the heart's pumping function.

12 Jun 2019

UIC researchers describe role of unique pressure-sensing protein in lung edema

Researchers at the University of Illinois at Chicago describe for the first time the role of a unique, pressure-sensing protein in the development of lung edema -- a condition in which chronic high vascular pressure in the lungs causes fluid from the bloodstream to enter the air spaces of the lungs.

11 Jun 2019

Early life adversity and high levels of FKBP5 protein amplify anxiety-like behavior

Researchers continue to dig for molecular clues to better understand how gene-environment interactions influence neuropsychiatric disease risk and resilience.

11 Jun 2019

Smarter, more educated people get a cognitive 'head start', but aren't protected from Alzheimer's

In a search for clues to what may delay or prevent Alzheimer's disease, Johns Hopkins Medicine scientists report that smarter, more educated people aren't protected from the disease, but do get a cognitive "head start" that may keep their minds functioning better temporarily.

From Johns Hopkins Medicine 11 Jun 2019

Smart phone plus nanoscale porous silicon equals simple home medical tests

The simplest home medical tests might look like a deck of various silicon chips coated in special film, one that could detect drugs in the blood, another for proteins in the urine indicating infection, another for bacteria in water and the like

11 Jun 2019

Novel agent shown to have dual mechanism of action to eliminate cancer

Results from a study spearhead by researchers at the Vall d´Hebron Institute of Oncology (VHIO), show that the blockade of the multi-functional cytokine LIF induces tumor-infiltrating T Cells to hone in on and eliminate cancer.

11 Jun 2019

Complex molecular conversation is key to the establishment of 'hot tumor'

A Ludwig Cancer Research study has deciphered a complex molecular conversation between cancer and immune cells that is key to orchestrating the successful invasion of tumors by T cells that kill cancer cells.

11 Jun 2019

Doctors urge hospitals to reconsider the type of fluids used to treat children with sepsis

Doctors have urged hospitals around the world to reconsider the type of fluids used to treat children gravely ill with sepsis.

11 Jun 2019

Study shows how SIRT1 plays key role in maintaining the regenerative potential of leukemic stem cells

Patients with chronic myeloid leukemia can be treated with tyrosine kinase inhibitors. While these effective drugs lead to deep remission and prolonged survival, primitive leukemia stem cells resist elimination during the remission and persist as a major barrier to cure.

11 Jun 2019

Study suggests therapeutic solutions for pantothenate kinase-associated neurodegeneration

The scientific research team from the Universidad Pablo de Olavide led by doctor José Antonio Sánchez Alcázar has published a new study in the international magazines Molecular Neorubiology and Neural Regeneration Research.

11 Jun 2019

Unhealthy gut microbiome may make breast cancers more aggressive finds study

A new study from the researchers at the University of Virginia Cancer Center connects an unhealthy gut microbiome with breast cancer that can become invasive and spread to other organs faster. The results of the study were published in the latest issue of the journal Cancer Research.

10 Jun 2019

First chemoimmunotherapy regimen approved by FDA for patients with diffuse large B-cell lymphoma

Today, the U.S. Food and Drug Administration granted accelerated approval to Polivy (polatuzumab vedotin-piiq), in combination with the chemotherapy bendamustine and a rituximab product (a combination known as "BR"), to treat adult patients with diffuse large B-cell lymphoma (DLBCL) that has progressed or returned after at least two prior therapies.

10 Jun 2019

Our tears may one day be used to detect glaucoma

Contrary to what many of us think, high pressure inside the eye does not define glaucoma and investigators want to know if the proteins circulating in the fluid of our eyes might.

10 Jun 2019

Proteasome inhibitors show potential for combating multidrug-resistant malaria

Proteasome inhibitors have significant promise as components of novel combination therapies to treat multidrug-resistant malaria, according to a study published June 6 in the open-access journal PLOS Pathogens by David Fidock, Caroline Ng, and Barbara Stokes of Columbia University Irving Medical Center, Matthew Bogyo of Stanford University School of Medicine, and colleagues.

From PLOS ONE 10 Jun 2019

Roche Diagnostics launches first in vitro diagnostic ROS1 immunohistochemistry assay

Roche Diagnostics today announced the launch of the VENTANA ROS1 Antibody, the first and only in vitro diagnostic ROS1 immunohistochemistry assay. The test detects the presence of ROS1 protein in tissue, and may be useful in identifying ROS1-positive lung cancer cases.

From Roche Sequencing and Life Science 10 Jun 2019

New web-based Advanced QC Peer Group program allows labs to compare data

Advanced Instruments, LLC announces the launch of their new web-based Advanced QC Peer Group program that allows laboratories to compare their osmometer serum and urine QC to their peers’ data on a real-time and monthly basis.

From Advanced Instruments 10 Jun 2019

EAF2000 advances complex charged molecule studies

Postnova Analytics reports on growing use of its pioneering EAF2000 system to separate and characterize complex proteins, antibodies and viruses as well as charged nanoparticles, colloids and polymers.

From Postnova Analytics 10 Jun 2019

Scientists discover the change in activity of neutrophils during cancer development

International group of scientists in the joint study of the laboratory of the Wistar Institute, University of Pittsburgh and I.M. Sechenov First Moscow State Medical University discovered the change in activity of one of the immune cells types called neutrophils during the cancer development: they begin to prevent other immune cells from fighting tumor and thus decelerate treatment.

10 Jun 2019

Bruker launches timsTOF fleX with ESI/MALDI capability for SpatialOMx at ASMS 2019

Bruker Daltonics has launched a novel timsTOF fleX mass spectrometer which combines ESI/MALDI capability for SpatialOMx on a single instrument.

From Bruker Daltonics 10 Jun 2019

Protein C News and Research

Researchers provide insight into unintended consequence of immune checkpoint inhibitors

New therapeutic approach utilizes endogenous processes to enhance cardiac repair

UIC researchers describe role of unique pressure-sensing protein in lung edema

Early life adversity and high levels of FKBP5 protein amplify anxiety-like behavior

Smarter, more educated people get a cognitive 'head start', but aren't protected from Alzheimer's

Smart phone plus nanoscale porous silicon equals simple home medical tests

Novel agent shown to have dual mechanism of action to eliminate cancer

Complex molecular conversation is key to the establishment of 'hot tumor'

Doctors urge hospitals to reconsider the type of fluids used to treat children with sepsis

Study shows how SIRT1 plays key role in maintaining the regenerative potential of leukemic stem cells

Study suggests therapeutic solutions for pantothenate kinase-associated neurodegeneration

Unhealthy gut microbiome may make breast cancers more aggressive finds study

First chemoimmunotherapy regimen approved by FDA for patients with diffuse large B-cell lymphoma

Our tears may one day be used to detect glaucoma

Proteasome inhibitors show potential for combating multidrug-resistant malaria

Roche Diagnostics launches first in vitro diagnostic ROS1 immunohistochemistry assay

New web-based Advanced QC Peer Group program allows labs to compare data

EAF2000 advances complex charged molecule studies

Scientists discover the change in activity of neutrophils during cancer development

Bruker launches timsTOF fleX with ESI/MALDI capability for SpatialOMx at ASMS 2019

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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