Biochemistry News and Research

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Researchers find direct link between MCL1 protein and cell-cycle checkpoint protein

Human cells respond to stresses like DNA damage, metabolic imbalance and starvation by first trying to repair the problem.

5 Apr 2020

Investigating Human Disease with Mass Spectrometry-based Proteomics

Dr. Andrew Webb describes how his lab uses mass spectrometry-based techniques to understand the role of post-translational modifications in human disease.

From Bruker Daltonics 3 Apr 2020

New study overturns ‘snapshot’ model of cell cycle accepted since 1974

Cells have a big decision: Should they replicate or sleep? Healthy cells can go either way. Cancer cells' replication switches are stuck in the 'on' position.

2 Apr 2020

New study offers clues to why autism is more common in boys than in girls

A new study in Neuron offers clues to why autism spectrum disorder is more common in boys than in girls. National Institutes of Health scientists found that a single amino acid change in the NLGN4 gene, which has been linked to autism symptoms, may drive this difference in some cases.

2 Apr 2020

Web portal provides information on how to decontaminate used N95 masks

As health workers and first responders in the United States try to stem a pandemic without adequate protective gear, health officials are forced to consider a stopgap - decontaminating and reusing N95 masks to shield those whose jobs expose them to the virus that causes COVID-19.

2 Apr 2020

Inhibiting the iron transport could halt tuberculosis

The bacteria that cause tuberculosis need iron to survive. Researchers at the University of Zurich have now solved the first detailed structure of the transport protein responsible for the iron supply.

1 Apr 2020

UVA researchers find way to enhance cancer outcomes by examining patients' genetic data

By mining a vast trove of genetic data, researchers at the University of Virginia School of Medicine are enhancing doctors’ ability to treat cancer, predict patient outcomes and determine which treatments will work best for individual patients.

30 Mar 2020

Gene that could affect the progress of ALS discovered

Researchers from the Zuckerman Institute at Columbia University have successfully found a gene that could work towards accelerating the progression of ALS or amyotrophic lateral sclerosis. The study titled, "The loss of TBK1 kinase activity in motor neurons or in all cell types differentially impacts ALS disease progression in SOD1 mice," was published in the latest issue of the journal Neuron.

29 Mar 2020

Research characterizes iPS87 cell line as cancer-inducing, stem cell-like cell line

Oncotarget Volume 11, Issue 12 reported outside its natural niche, the cultured prostate cancer stem cells lost their tumor-inducing capability and stem cell marker expression after approximately 8 transfers at a 1:3 split ratio.

27 Mar 2020

Advancing CAR T-cell therapy for treatment of solid tumors

The full title of the research is "The study of the mechanisms of effectiveness of T-cells CAR-T towards solid tumors"; it was supported by nonprofit RakFond (Cancer Fund) and CyStoreLab (a resident of Skolkovo).

25 Mar 2020

A genetic toolkit to produce multifunctional magnetic nanoparticles

Magnetic bacteria might soon be used for the production of novel biomaterials. A team of microbiologists at the University of Bayreuth led by Prof. Dr. Dirk Schüler developed a modular system for the genetic reprogramming of bacteria, thereby turning the organisms into cell factories for multifunctional magnetic nanoparticles that combine various useful functions and properties.

25 Mar 2020

Cancer could potentially be treated with new immunotherapy approach, say researchers

Researchers have made a discovery about EGR4 that could instigate a new immunotherapy approach to treating cancer.

25 Mar 2020

Study identifies brake on immune activity raising new possibilities for anticancer therapy

The immune system is like a carefully regulated machine, complete with its own built-in "brakes" that prevent it from overreacting and causing excess inflammation in otherwise healthy tissues.

25 Mar 2020

Cannabidiol helps fight antibiotic-resistant bacteria

Since the discovery of penicillin in 1928 by Sir Alexander Fleming, antibiotics have saved millions of lives from fatal infections world-wide. However, with time bacteria have developed mechanisms to escape the effects of antibiotics - they have become resistant.

24 Mar 2020

Research reveals important mechanism in the repair of DNA double-strand breaks

Scientists have revealed an important mechanism in the repair of DNA double-strand breaks, according to new research published today in eLife.

24 Mar 2020

OncoMX knowledgebase improves exploration of cancer biomarkers and related evidence

The OncoMX knowledgebase will improve the exploration and research of cancer biomarkers in the context of related evidence, according to a recent article from the George Washington University.

23 Mar 2020

Tel Aviv University joins volunteer initiative to improve detection of novel coronavirus in Israel

Israeli hospitals and universities, including Tel Aviv University, have joined forces to build an enormous student volunteer base to expand and improve the detection of people infected with novel coronavirus all over Israel.

22 Mar 2020

A review of the literature on acute promyelocytic leukemia

Oncotarget Volume 11, Issue 11 reported that relapsed APL, particularly in the high-risk subset of patients, remains an important clinical problem.

22 Mar 2020

Lance Liotta receives $72,000 for collaborative project

Lance Liotta, Co-Director, Applied Proteomics and Molecular Medicine, received $72,000 from Queensland University of Technology for the project: "The Systems Biochemistry of Adaptation in Cellular Protein Networks." Australian Research Council Future Fellowship (total $784,680).

22 Mar 2020

CARB-X awards $2.86M to develop novel oral antibiotic to treat drug-resistant gonorrhea

Up to $2.86M has been awarded to a research team including Penn State scientists to develop a new oral antibiotic to treat multidrug-resistant gonorrhea, a sexually transmitted disease caused by bacteria that have developed resistance to all but one existing antibiotic.

20 Mar 2020

Biochemistry News and Research

Researchers find direct link between MCL1 protein and cell-cycle checkpoint protein

Investigating Human Disease with Mass Spectrometry-based Proteomics

New study overturns ‘snapshot’ model of cell cycle accepted since 1974

New study offers clues to why autism is more common in boys than in girls

Web portal provides information on how to decontaminate used N95 masks

Inhibiting the iron transport could halt tuberculosis

UVA researchers find way to enhance cancer outcomes by examining patients' genetic data

Gene that could affect the progress of ALS discovered

Research characterizes iPS87 cell line as cancer-inducing, stem cell-like cell line

Advancing CAR T-cell therapy for treatment of solid tumors

A genetic toolkit to produce multifunctional magnetic nanoparticles

Cancer could potentially be treated with new immunotherapy approach, say researchers

Study identifies brake on immune activity raising new possibilities for anticancer therapy

Cannabidiol helps fight antibiotic-resistant bacteria

Research reveals important mechanism in the repair of DNA double-strand breaks

OncoMX knowledgebase improves exploration of cancer biomarkers and related evidence

Tel Aviv University joins volunteer initiative to improve detection of novel coronavirus in Israel

A review of the literature on acute promyelocytic leukemia

Lance Liotta receives $72,000 for collaborative project

CARB-X awards $2.86M to develop novel oral antibiotic to treat drug-resistant gonorrhea

Understanding the DNA Damage Response in Innate Immunity eBook

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