Immune Response News and Research

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Novel RNA sense-and-respond circuit harnesses the force of enzymes to develop better drugs

More than twelve billion doses of mRNA vaccines have been administered globally since the start of the COVID pandemic, saving millions of lives. But RNA-based therapies for other diseases have so far proven more challenging to develop.

20 Mar 2023

SARS-CoV-2 infection damages the CD8+ T cell response to vaccination

The magnitude and quality of a key immune cell's response to vaccination with two doses of the Pfizer-BioNTech COVID-19 vaccine were considerably lower in people with prior SARS-CoV-2 infection compared to people without prior infection, a study has found.

20 Mar 2023

Upgraded tumor model points the way toward more effective cancer therapies

Tumor cells won't show their true selves in a petri dish, isolated from other cells.

20 Mar 2023

Poor inflammatory immune response in obese patients increases susceptibility to severe COVID-19

Individuals who are obese may be more susceptible to severe COVID-19 because of a poorer inflammatory immune response, say Cambridge scientists.

20 Mar 2023

New SARS-CoV-2 Omicron XBB.1.5 variant has high transmissibility and infectivity, study finds

COVID-19 has caused significant global panic after its rapid emergence more than 3 years ago. Although we now have highly effective vaccines against the SARS-CoV-2 virus, which causes COVID-19, scientists continue to study emerging SARS-CoV-2 variants in order to safeguard public health and devise global preventive strategies against emerging variants.

20 Mar 2023

What role does dysbiosis play in Parkinson's disease?

The current study, published in the journal Revue Neurologique, is based on the hypothesis that dysbiosis, or unhealthy variations in the gut and oral microbiota, is a key component of PD pathogenesis.

19 Mar 2023

Inadequate sleep associated with lower vaccine-induced humoral immunity

Researchers assess the association between the duration of sleep and humoral responses to vaccination.

19 Mar 2023

Study implicates gut microbiome and immune response in hospital-acquired infections

In a recent study published in the journal Nature Medicine, researchers at the University of Calgary analyzed the dynamics of fecal microbiota and conducted single-cell profiling of inflammatory responses and systemic immunity to determine associations between gut microbiome dysbiosis and an increased risk of nosocomial infections.

16 Mar 2023

Scientists develop genetically defined mouse models for multiple myeloma subtypes

A team of scientists led by Martin Janz and Klaus Rajewsky at the Max Delbrück Center has successfully generated genetically defined mouse models for two subtypes of multiple myeloma.

16 Mar 2023

Bat stem cells reveal how bats survive in a virus-filled environment

A recent Cell journal study tested the hypothesis that bats genetically induce the virus for immune evasion and provide fertile ground for replication.

15 Mar 2023

High consumption of common artificial sweetener lowers activation of T-cells in mice

Scientists at the Francis Crick Institute have found that high consumption of a common artificial sweetener, sucralose, lowers activation of T-cells, an important component of the immune system, in mice.

15 Mar 2023

Research uncovers a possible explanation for sex differences in pancreatic cancer

Immunotherapy is an effective form of therapy for different types of cancer. However, for pancreatic cancer, its effect is limited and differs between men and women.

15 Mar 2023

Children's immunity to COVID-19 provided by common colds

During the pandemic, it became clear that children who contracted COVID-19 became less ill than adults.

15 Mar 2023

Lassa virus vaccine induces rapid protection in an animal model

Scientists have developed a novel Lassa vaccine using a recombinant measles virus and tested its protective efficacy against Lassa fever. A single vaccine dose has been found to induce a rapid and robust immune response in monkeys with pre-existing immunity against the measles virus.

14 Mar 2023

Host immune system forms small lesions in the intestines in response to bacterial infection

Yersinia bacteria cause a variety of human and animal diseases, the most notorious being the plague, caused by Yersinia pestis.

14 Mar 2023

Study suggests mRNA vaccines decouple SARS-CoV-2 immunity from autoantibody responses observed during acute COVID-19

Researchers investigated whether mRNA technology-based COVID-19 vaccines promote the development of autoantibodies.

14 Mar 2023

Study suggests a new way to develop intra-tumor immunotherapies to fight head and neck cancer

Researchers at University of California San Diego School of Medicine and Moores Cancer Center at UC San Diego Health have identified a strong association between the product of a gene expressed in most cancers, including the most common type of head and neck cancer, and elevated levels of white blood cells that produce antibodies within tumors.

13 Mar 2023

Immune Response News and Research

Novel RNA sense-and-respond circuit harnesses the force of enzymes to develop better drugs

SARS-CoV-2 infection damages the CD8+ T cell response to vaccination

Upgraded tumor model points the way toward more effective cancer therapies

Poor inflammatory immune response in obese patients increases susceptibility to severe COVID-19

New SARS-CoV-2 Omicron XBB.1.5 variant has high transmissibility and infectivity, study finds

What role does dysbiosis play in Parkinson's disease?

Inadequate sleep associated with lower vaccine-induced humoral immunity

Study implicates gut microbiome and immune response in hospital-acquired infections

Scientists develop genetically defined mouse models for multiple myeloma subtypes

Bat stem cells reveal how bats survive in a virus-filled environment

High consumption of common artificial sweetener lowers activation of T-cells in mice

Research uncovers a possible explanation for sex differences in pancreatic cancer

Children's immunity to COVID-19 provided by common colds

Lassa virus vaccine induces rapid protection in an animal model

Host immune system forms small lesions in the intestines in response to bacterial infection

Study suggests mRNA vaccines decouple SARS-CoV-2 immunity from autoantibody responses observed during acute COVID-19

Study suggests a new way to develop intra-tumor immunotherapies to fight head and neck cancer

How does temperature affect host responses to SARS-CoV-2 and IAV infection in human nasal epithelial cells?

Innate immune molecule could be at the root of ALS

Simple blood test could easily pinpoint epileptic seizures

Understanding the DNA Damage Response in Innate Immunity eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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