Nicotine News and Research

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Nicotine is an alkaloid found in the nightshade family of plants (''Solanaceae'') which constitutes approximately 0.6–3.0% of dry weight of tobacco, with biosynthesis taking place in the roots, and accumulating in the leaves.

UC San Diego researchers receive grant to study pharmacogenomics for bipolar disorder

An international team, led by University of California, San Diego School of Medicine researchers, has been awarded a $6.5 million grant from the National Institutes of Health (NIH) to study the pharmacogenomics of a key mood-stabilizing drug used to treat bipolar disorder.

8 Sep 2010

NIH awards St. Jude $8.6M to focus on anticancer agent research in children

With its new expansion of the Pharmacogenomics Research Network (PGRN), the National Institutes of Health (NIH) awarded St. Jude Children's Research Hospital a prestigious grant to focus on anticancer agent research in children.

8 Sep 2010

Penn receives $12M NIH grant to study pharmacogenetics of nicotine addiction treatment

A variety of smoking cessation treatments are currently available for the more than 18 million adult Americans try to quit smoking each year, but success rates vary widely. Despite the importance of quitting smoking, more personalized approaches to smoking cessation treatment are needed to help smokers pick the right method that will work best for them. A major new personalized medicine clinical trial, led by addiction researchers at the University of Pennsylvania, will study how a smokers' genetic make-up influences their quitting success.

8 Sep 2010

UCSF scientists to receive two grants for personalized medicine research

UCSF scientists will receive two grants totaling $15.1 million over the next five years to expand their research into how genes affect an individual's response to medication and to strengthen a global network of researchers involved in these efforts.

7 Sep 2010

American Cancer Society attacks electronic cigarettes while number of users increase

The American Cancer Society continues to attack electronic cigarettes and falsely label them as dangerous and ineffective, while the number of people using the products is increasing by 20,000 to 30,000 a week. Despite the ACS's claims, e cigarette reviews by consumers are still flooding in all over the Internet that smokers who are switching to e cigarettes and e liquid are breathing, tasting, and sleeping better than they ever did while smoking traditional cigarettes.

3 Sep 2010

Diabetes drug metformin exhibits potential against tobacco-induced lung tumors

Metformin, a drug commonly used to treat type 2 diabetes, shows potential in the prevention of tobacco-induced lung tumors, according to early research conducted at the National Cancer Institute (NCI).

3 Sep 2010

Purdue University researchers develop new type of pump for drug-delivery patches

Purdue University researchers have developed a new type of pump for drug-delivery patches that might use arrays of "microneedles" to deliver a wider range of medications than now possible with conventional patches.

2 Sep 2010

Nabi Biopharmaceuticals, Diosynth sign long-term commercial manufacturing agreement

Nabi Biopharmaceuticals announced today that it has entered into a long-term commercial manufacturing agreement with Diosynth RTP, Inc. for the manufacture of Drug Substance integral to the production of NicVAX, Nabi's innovative and proprietary investigational vaccine for the treatment of nicotine addiction and prevention of smoking relapse.

2 Sep 2010

Consuming variety of fruits, vegetables may decrease squamous cell lung cancer risk: Study

Adding a variety of vegetables to one's diet may help decrease the chance of getting lung cancer, and adding a variety of fruits and vegetables may decrease the risk of squamous cell lung cancer, especially among smokers.

2 Sep 2010

Anti-smoking measures beefed up

Tasmanians are looking at one of the tightest tobacco control measures ever adopted. The Tasmanian Government is proposing a no-smoking zone at almost all public places including shopping malls and sporting venues and introducing smoke-free buffer zone around children's playgrounds.

31 Aug 2010

Canada should publicly fund smoking cessation pharmacotherapies: CMAJ

Canada should follow the lead of Quebec, Australia and the United Kingdom by publicly funding smoking cessation pharmacotherapies, states an editorial in CMAJ http://www.cmaj.ca/embargo/cmaj101140.pdf.

30 Aug 2010

Study finds common risk factors linked with painkiller addiction

A new Geisinger study begins to unlock the puzzle of painkiller (opioid) addiction - why some people are more likely to become addicted than others. Geisinger investigators have found that patients with four common risk factors have a significantly higher risk of addiction. In addition, a history of severe drug dependence and drug abuse compounds the risk.

30 Aug 2010

Cigarettes as mood enhancers increase risk of depression

While some teenagers may puff on cigarettes to 'self-medicate' against the blues, scientists at the University of Toronto and the University of Montreal have found that smoking may actually increase depressive symptoms in some adolescents. Published in the journal Addictive Behaviors, the findings are part of the long-term Nicotine Dependence in Teens (NDIT) study based at the University of Montreal Hospital Research Centre.

27 Aug 2010

Alexza Pharmaceuticals licenses Staccato nicotine technology to Cypress Bioscience

Alexza Pharmaceuticals, Inc. announced today that it has licensed its Staccato nicotine technology to Cypress Bioscience, Inc. The Staccato nicotine technology is a novel electronic multidose delivery system designed to help people stop smoking. The Staccato nicotine technology is intended to improve on a well-validated smoking cessation approach by delivering nicotine via inhalation, mimicking the nicotine effects of smoking without the harmful side effects associated with cigarettes.

26 Aug 2010

New test helps to measure smoker's mainstream smoke deliveries of select chemicals per cigarette

A test for one of the thousands of chemicals in cigarette smoke has the potential for more accurately estimating smokers' mouth level exposure and may have applications for developing custom-tailored quitting approaches for the more than 43 million people in the United States who still smoke, and hundreds of millions elsewhere, scientists said here today.

26 Aug 2010

Nabi receives US patent for treatment and prevention of nicotine addiction with NicVAX conjugate vaccines

Nabi Biopharmaceuticals announced the receipt of a patent for treating and preventing nicotine addiction with NicVAX® and related nicotine conjugate vaccines. The United States Patent and Trademark office issued U.S. Patent No. 7,776,620 entitled "Hapten-carrier conjugates for treating and preventing nicotine addiction" for the exclusive use of methods for treating and preventing nicotine addiction with NicVAX and related nicotine vaccines. This patent runs through December 2018.

26 Aug 2010

Researchers find medication for diabetes, smoking cessation

The script for two research teams inducted today into the American Chemical Society (ACS) scientific "hall of fame" the ACS Heroes of Chemistry is a tale of two pills. One team invented a medication that helps people with diabetes control their blood sugar levels. The second team invented a medicine that helps people stop smoking, an addiction that experts regard as today's single greatest preventable cause of death worldwide.

23 Aug 2010

NHS Stop Smoking Services helps 373,954 people to quit smoking during 2009-10

NHS Stop Smoking Services helped 373,954 people to quit smoking during 2009-10 - a higher number than ever before.

21 Aug 2010

Even low-level exposure to cigarette smoke affects gene function in lungs

Casual smokers may think that smoking a few cigarettes a week is "no big deal." But according to new research from physician-scientists at NewYork-Presbyterian Hospital/Weill Cornell Medical Center, having an infrequent smoke, or being exposed to secondhand smoke, may be doing more harm than people may think. The findings may further support public smoking bans, say the authors.

20 Aug 2010

E Cigarettes National announces improved atomizer design

E Cigarettes National has an e cigarette, also referred to as smokeless cigarettes, that has a different design on their atomizers that has pushed their electronic cigarette starter kit to the top of the chain in the rapidly growing e cigarette market.

19 Aug 2010

Nicotine News and Research

Further Reading

UC San Diego researchers receive grant to study pharmacogenomics for bipolar disorder

NIH awards St. Jude $8.6M to focus on anticancer agent research in children

Penn receives $12M NIH grant to study pharmacogenetics of nicotine addiction treatment

UCSF scientists to receive two grants for personalized medicine research

American Cancer Society attacks electronic cigarettes while number of users increase

Diabetes drug metformin exhibits potential against tobacco-induced lung tumors

Purdue University researchers develop new type of pump for drug-delivery patches

Nabi Biopharmaceuticals, Diosynth sign long-term commercial manufacturing agreement

Consuming variety of fruits, vegetables may decrease squamous cell lung cancer risk: Study

Anti-smoking measures beefed up

Canada should publicly fund smoking cessation pharmacotherapies: CMAJ

Study finds common risk factors linked with painkiller addiction

Cigarettes as mood enhancers increase risk of depression

Alexza Pharmaceuticals licenses Staccato nicotine technology to Cypress Bioscience

New test helps to measure smoker's mainstream smoke deliveries of select chemicals per cigarette

Nabi receives US patent for treatment and prevention of nicotine addiction with NicVAX conjugate vaccines

Researchers find medication for diabetes, smoking cessation

NHS Stop Smoking Services helps 373,954 people to quit smoking during 2009-10

Even low-level exposure to cigarette smoke affects gene function in lungs

E Cigarettes National announces improved atomizer design

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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