Genetic News and Research

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Study identifies potent molecular mechanism for insecticide resistance in sandfly species

A study led by LSTM identifies a potent molecular mechanism for insecticide resistance in the world's most medically-important sandfly species and develops DNA-diagnostics for monitoring future impact on visceral leishmaniasis control and elimination programs.

5 May 2017

Aroma researcher highlights stimulating power of smell in humans

We might be forgiven for thinking that a dog's sense of smell is more sensitive than our own. After all, our other senses seem to dominate daily life.

5 May 2017

New conference aims to improve understanding of how advances in genomics influence society

From prenatal genetic screening to the genetic testing of women with family histories of breast cancer, genomics is rapidly becoming a fixture in our lives.

5 May 2017

Study sheds light on neural mechanisms of Fragile X syndrome

A collaboration between scientists in Belgium, the United States, Norway, France and the UK has resulted in a study that sheds light on the neural mechanisms of Fragile X syndrome.

5 May 2017

Easing cellular traffic jams in Huntington’s disease may save brain cells

Working with mouse, fly and human cells and tissue, Johns Hopkins researchers report new evidence that disruptions in the movement of cellular materials in and out of a cell's control center - the nucleus- appear to be a direct cause of brain cell death in Huntington's disease, an inherited adult neurodegenerative disorder.

5 May 2017

Genetic study outlines path to personalize breast cancer risk assessment and treatment

Although the odds of developing breast cancer are nearly identical for black and white women, black women are 42 percent more likely to die from the disease. This mortality gap – driven by social and environmental, as well as biological factors – continues to persist.

4 May 2017

Molecular mechanism reprograms tumor cells to drive treatment resistance in advanced prostate cancer

Columbia University Medical Center researchers have discovered a molecular mechanism that reprograms tumor cells in patients with advanced prostate cancer, reducing their response to anti-androgen therapy.

4 May 2017

Genetic findings may offer clues to accurate diagnosis and treatment of type 1.5 diabetes

Researchers investigating a form of adult-onset diabetes that shares features with the two better-known types of diabetes have discovered genetic influences that may offer clues to more accurate diagnosis and treatment.

4 May 2017

International consensus addresses research bottlenecks to diagnose rare genetic diseases

A worldwide consensus co-authored by more than 40 scientists sets out ways to address research bottlenecks as the international community strives to diagnose most rare genetic diseases by 2020.

4 May 2017

Study finds higher rates of suicidal thoughts and attempts among transgender adults

Suicidal thoughts and attempts by adult transgender individuals were 14 and 22 times higher, respectively, than rates for the general public, according to a new study published in Transgender Health, a peer-reviewed open access journal from Mary Ann Liebert, Inc., publishers. The article is available open access on the Transgender Health website.

4 May 2017

American Cancer Society awards new $792,000 grant to Yale researcher

The American Cancer Society, the largest non-government, not-for-profit funding source of cancer research in the United States, has approved funding of a new research grant totaling $792,000 to a researcher at Yale University.

4 May 2017

Scientists uncover thousands of human genes that are expressed differently in the two sexes

Men and women differ in obvious and less obvious ways -- for example, in the prevalence of certain diseases or reactions to drugs. How are these connected to one's sex? Weizmann Institute of Science researchers recently uncovered thousands of human genes that are expressed -- copied out to make proteins -- differently in the two sexes.

4 May 2017

$New mutation predisposes patients under osteoporosis treatment to atypical femur fractures, study finds$

New mutation predisposes patients under osteoporosis treatment to atypical femur fractures, study finds

A team of researchers of the University of Barcelona and the Hospital del Mar Medical Research Institute have discovered a new mutation that has an impact on the bone so that it is vulnerable to the bisphosphonate, a drug used to treat osteoporosis.

4 May 2017

New drug mimics health effects of exercise, say researchers

Scientists have managed to mimic the health effects of exercise in mice, simply by using a pill, according to a study published in Cell Metabolism. The drug activated a genetic pathway that is triggered by running, which led mice to burn off more fat and increase their stamina levels, despite them being sedentary.

4 May 2017

Synthetic biologists re-engineer yeast cells to manufacture antibiotic penicillin

The synthetic biologists from Imperial College London have re-engineered yeast cells to manufacture the nonribosomal peptide antibiotic penicillin. In laboratory experiments, they were able to demonstrate that this yeast had antibacterial properties against streptococcus bacteria.

4 May 2017

Researchers use mathematical modeling to find effective chemotherapy treatments for cancer patients

A team of Florida State University researchers is using mathematical modeling to find the best and most effective chemotherapy treatments for cancer patients.

4 May 2017

Lethal DNA re-replication may be used to attack cancer cells

DNA over-replication is a phenomenon that can have devastating consequences for proliferating cells. When parts of the genome are duplicated more than once, cells suffer from 'genomic instability' (alterations to the structure, composition and/or number of chromosomes), and this process gives rise to aberrant cells as those detected in many carcinomas.

4 May 2017

Lost function of genes impairs development of motor skills in maturing mice

Scientists report in Neuron the lost function of two genes prevents infant laboratory mice from developing motor skills as they mature into adults. Researchers also suggest in their study that people with certain motor development disabilities be tested to see if they have mutant forms of the same genes.

3 May 2017

Study reveals gluten diet is not connected with heart disease among non-celiac people

The study findings published online in the British Medical Journal today reveal that the intake of a long-term gluten diet is not connected with coronary heart disease among people without celiac disease.

3 May 2017

Researchers identify key player in initiation and progression of melanoma

Identification and functional validation of proteins involved in tumorigenesis are essential steps toward advancing cancer precision medicine. In The Journal of Clinical Investigation researchers from VIB, KU Leuven together with colleagues from INSERM now report the important role for FES in the initiation and progression of melanoma, a malignant type of skin cancer, that is notoriously quick to metastasize and that responds poorly to existing cancer treatments.

3 May 2017

Genetic News and Research

Study identifies potent molecular mechanism for insecticide resistance in sandfly species

Aroma researcher highlights stimulating power of smell in humans

New conference aims to improve understanding of how advances in genomics influence society

Study sheds light on neural mechanisms of Fragile X syndrome

Easing cellular traffic jams in Huntington’s disease may save brain cells

Genetic study outlines path to personalize breast cancer risk assessment and treatment

Molecular mechanism reprograms tumor cells to drive treatment resistance in advanced prostate cancer

Genetic findings may offer clues to accurate diagnosis and treatment of type 1.5 diabetes

International consensus addresses research bottlenecks to diagnose rare genetic diseases

Study finds higher rates of suicidal thoughts and attempts among transgender adults

American Cancer Society awards new $792,000 grant to Yale researcher

Scientists uncover thousands of human genes that are expressed differently in the two sexes

New mutation predisposes patients under osteoporosis treatment to atypical femur fractures, study finds

New drug mimics health effects of exercise, say researchers

Synthetic biologists re-engineer yeast cells to manufacture antibiotic penicillin

Researchers use mathematical modeling to find effective chemotherapy treatments for cancer patients

Lethal DNA re-replication may be used to attack cancer cells

Lost function of genes impairs development of motor skills in maturing mice

Study reveals gluten diet is not connected with heart disease among non-celiac people

Researchers identify key player in initiation and progression of melanoma

eBook: Using iPSCs models for human disease research and drug discovery eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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