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Researchers caution use of chloroquine therapy for patients at higher risk of heart rhythm abnormalities

A patient who met many of the published safety guidelines for chloroquine therapy against COVID-19 was observed to have a very abnormal ECG pattern after treatment began, leading to multiple episodes of torsade de pointes (TdP), a life-threatening arrhythmia in which the lower chambers of the heart beat out of sync with the upper chambers.

18 Jun 2020

Not having surgery lowers risk of stroke, death in patients with brain AVMs

For patients with brain arteriovenous malformations, not having surgery or getting radiation therapy can result in an almost 70-per-cent lower risk of having a stroke or dying, researchers find.

18 Jun 2020

Study reveals how COVID-19 pandemic has impacted cancer patients' quality of life

Patients with cancer face a serious dilemma during the COVID-19 pandemic, as staying at home could increase their risk of cancer progression, while visiting the hospital for treatment could increase their risk of becoming infected with the virus that causes COVID-19.

18 Jun 2020

Neighborhood socioeconomic status and household crowding associated with COVID-19

A study of nearly 400 pregnant women in New York City is among the first to show that lower neighborhood socioeconomic status and greater household crowding increase the risk of becoming infected with SARS-CoV-2, the virus that causes COVID-19.

18 Jun 2020

Novel SARS-CoV-2 antibody cocktail impeccably mimics human antibody response

By using both humanized mice and convalescent patients, the researchers from the US and Singapore successfully generated non-competing and highly potent monoclonal antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein that could potentially be combined to form antibody cocktails. Their groundbreaking paper is published in the leading research journal Science.

18 Jun 2020

Discovery of key steps in kidney formation could have implications for treating renal diseases

The discovery of how certain key structures in the kidneys are formed could have important implications for treating renal fibrosis (or scarring), a feature of chronic kidney disease (CKD), according to a new study by a researcher at Massachusetts General Hospital.

18 Jun 2020

COVID-19 collaborative program reduces mortality in long-term care facilities

A collaborative program developed at UVA Health to work with local long-term care facilities control COVID-19 is saving lives and offers a model for communities across the country, a new scientific paper reports.

18 Jun 2020

DFG establishes interdisciplinary commission to strengthen pandemic research

Against the background of the current coronavirus pandemic, the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) is to establish an interdisciplinary commission for pandemic research.

18 Jun 2020

Certain patients who receive hospital care for COVID-19 exhibit clear signs of brain injury

Certain patients who receive hospital care for coronavirus infection (COVID-19) exhibit clinical and neurochemical signs of brain injury, a University of Gothenburg study shows. In even moderate COVID-19 cases, finding and measuring a blood-based biomarker for brain damage proved to be possible.

18 Jun 2020

Research uncovers some of the secrets to longevity

University of Otago researchers have discovered some of the secrets to longevity with new research revealing not smoking and being social engaged throughout older age are common traits of New Zealand centenarians.

18 Jun 2020

Study reports ominous resurgence of silicosis

A new study appearing in the journal CHEST®, published by Elsevier, documents an increased incidence of silicosis, which progressed rapidly to massive pulmonary fibrosis in a significant proportion of patients who had previously worked artificial stone (AS), also called artificial quartz agglomerate or conglomerate, a popular new countertop material, despite the cessation of exposure after diagnosis.

18 Jun 2020

Study identifies a previously unknown mechanism that contributes to intestinal cancer

A MedUni Vienna study group has identified a previously unknown mechanism involved in the development of intestinal cancer: The bacterial microbiome activates the so-called immune checkpoint Ido1 in Paneth cells, a special cell that is only found in the gastrointestinal tract, thereby preventing local intestinal inflammation.

18 Jun 2020

Novel biomarkers required to triage and monitor severely ill COVID-19 patients

Diagnostics company SphingoTec GmbH ("sphingotec") announced today the results of a working group meeting of clinical experts that discussed the utility of sphingotec's diagnostic solutions for acute and critical care in supporting the triage, diagnosis, and management of severely ill COVID-19 patients.

18 Jun 2020

Managing pain after sports medicine procedures without opioids

A Henry Ford Hospital study published in the Journal of Arthroscopic and Related Surgery, has found that patients who underwent knee surgery and other types of sports medicine procedures could manage their pain without opioids or a minimal dosage.

18 Jun 2020

Diabetic ketoacidosis is a fatal complication in hospitalized COVID-19 patients

Diabetic ketoacidosis is a common and potentially fatal complication in hospitalized patients with COVID-19, according to a new clinical perspective published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

18 Jun 2020

Professor Louise Kenny appointed to NHSA board of directors

A PROMINENT North Professor will play a pivotal role in driving forward the vision of the Northern Health Science Alliance as she joins the leading life science cluster’s board.

18 Jun 2020

COVID-19 and blood group in aortic valve replacement

The COVID-19 pandemic has been found to cause disproportionate harm in patients with cardiovascular disease, especially among the elderly population, among other risk factors. However, a new study published on the preprint server medRxiv* in June 2020 is the first to report its clinical features in patients with aortic stenosis who have had a transcatheter aortic valve replacement (TAVR).

18 Jun 2020

Study in 'split brain' patients sheds new light on sleep slow waves

The particular kind of waves that the brain produces during sleep, which repeatedly sweep the surface of the cerebral cortex, travel through the anatomical "highways" that connect distant areas of the cortical mantle, a new study in The Journal of Neuroscience shows.

17 Jun 2020

C-Path's Transplant Therapeutics Consortium receives positive FDA response for its Letter of Intent

Critical Path Institute announced today that its Transplant Therapeutics Consortium has received a positive response to its Letter of Intent from the U.S. Food and Drug Administration detailing the decision to accept the Composite Biomarker Panel (iBox Scoring System) into the Center for Drug Evaluation and Research (CDER) Biomarker Qualification Program.

17 Jun 2020

Interventional treatment for brain AVMs could be more dangerous than the disease itself

For people with a brain arteriovenous malformation, a congenital vascular system defect, fate has a name: stroke.

17 Jun 2020

Hospital News and Research

Researchers caution use of chloroquine therapy for patients at higher risk of heart rhythm abnormalities

Not having surgery lowers risk of stroke, death in patients with brain AVMs

Study reveals how COVID-19 pandemic has impacted cancer patients' quality of life

Neighborhood socioeconomic status and household crowding associated with COVID-19

Novel SARS-CoV-2 antibody cocktail impeccably mimics human antibody response

Discovery of key steps in kidney formation could have implications for treating renal diseases

COVID-19 collaborative program reduces mortality in long-term care facilities

DFG establishes interdisciplinary commission to strengthen pandemic research

Certain patients who receive hospital care for COVID-19 exhibit clear signs of brain injury

Research uncovers some of the secrets to longevity

Study reports ominous resurgence of silicosis

Study identifies a previously unknown mechanism that contributes to intestinal cancer

Novel biomarkers required to triage and monitor severely ill COVID-19 patients

Managing pain after sports medicine procedures without opioids

Diabetic ketoacidosis is a fatal complication in hospitalized COVID-19 patients

Professor Louise Kenny appointed to NHSA board of directors

COVID-19 and blood group in aortic valve replacement

Study in 'split brain' patients sheds new light on sleep slow waves

C-Path's Transplant Therapeutics Consortium receives positive FDA response for its Letter of Intent

Interventional treatment for brain AVMs could be more dangerous than the disease itself

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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