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Former California state contractor sued over breach of HIV patient privacy

A security breach by a private company that contracted with California's public health department inadvertently allowed unauthorized access to the HIV status of 93 people, according to a lawsuit filed this week in San Francisco County Superior Court.

9 Apr 2018

ALS and frontotemporal dementia share genetic connections

Nearly half of all patients with amyotrophic lateral sclerosis (ALS), a fatal neuromuscular disorder, develop cognitive problems that affect memory and thinking.

9 Apr 2018

Study reveals how apoE4 gene confers risk for Alzheimer's disease in brain cells

Using human brain cells, scientists at the Gladstone Institutes discovered the cause of--and a potential solution for--the primary genetic risk factor for Alzheimer's disease, a gene called apoE4.

9 Apr 2018

Controlling blood pressure can prevent dementia in older African-Americans with hypertension

Controlling blood pressure with any of the commonly prescribed antihypertensive medications can prevent dementia in older African-Americans with hypertension according to a new study from Regenstrief Institute researchers.

9 Apr 2018

Using biomimicry for faster detection of disease outbreaks

Our immune systems are made up of billions of white blood cells searching for signs of infections and foreign invaders, ready to raise the alarm.

9 Apr 2018

Antiepileptic drug use linked to increased risk of Alzheimer's and dementia

The use of antiepileptic drugs is associated with an increased risk of Alzheimer's disease and dementia, according to a new study from the University of Eastern Finland and the German Center for Neurodegenerative Diseases, DZNE.

9 Apr 2018

Oxidative stress due to lack of tumor suppressor gene promotes cancer progression, study shows

Researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore have identified that RUNX3, a tumour suppressor gene absent in many cancer types, acts as a barrier against oxidative stress in cancer cells.

9 Apr 2018

Vascular stabilization biomarker helps optimize timing of anticancer therapies

Angiogenesis, the formation of new blood vessels, is essential for tumor growth. A new study reported in The American Journal of Pathology describes a vascular stabilization biomarker that can visualize blood vessel activity, thus optimizing the timing of anticancer therapies including anti-angiogenics.

9 Apr 2018

Nosopharm and UIC reveal pharmacology of new class of antibiotics to combat drug resistance

Nosopharm, a company dedicated to the research and development of new anti-infective drugs, and the University of Illinois at Chicago today announce the publication of a study in Molecular Cell on the mechanism of action of odilorhabdins, a new class of antibiotics to combat antibiotic resistance.

9 Apr 2018

U.S. population largely unaware of cancer drug shortages, study finds

The U.S. population is largely unaware that there are shortages in the availability of cancer drugs, according to a study published early online in CANCER, a peer-reviewed journal of the American Cancer Society.

9 Apr 2018

Scientists develop indices that provide information about prognosis of cancers

Researchers from the School of Medicine in Ribeirão Preto, at the University of São Paulo, in collaboration with international groups, have developed indices that provide information about the prognosis of cancers, aid in the choice of the most appropriate therapy to be used and identify potential targets for the development of new drugs.

6 Apr 2018

Johns Hopkins scientist calls for more integration of epigenetics and genetics research

In a review article published April 5 in the New England Journal of Medicine, scientist Andrew Feinberg, M.D., calls for more integration between two fields of DNA-based research: genetics and epigenetics.

6 Apr 2018

Scientists identify key genetic events responsible for initiating childhood leukemia

The key genetic events responsible for initiating the early stages of a type of childhood leukemia have been identified by scientists at The Institute of Cancer Research, London. Insights into the ‘founder’ genetic mutation for this type of leukemia, present in all the cancer cells, could be used in the development of new targeted drugs.

6 Apr 2018

Waking up “sleeping” stem cells in the brain could improve its ability to repair injury

Researchers have identified a new type of stem cell that could boost the brain’s ability to repair damage caused by brain injury or disease.

6 Apr 2018

Scientists create organoids that could help guide bladder cancer treatment

Researchers have created patient-specific bladder cancer organoids that imitate many of the features of real tumors and may therefore be used to study how cancer evolves.

6 Apr 2018

Novel technology gives rise to mouse pancreatic tumors that resemble human cancer

Novel technology developed at UT Health San Antonio gives rise to mouse pancreatic tumors that have the same traits as human pancreatic cancer. A U.S. patent is pending on the invention.

6 Apr 2018

Aging immune cells increase risk for macular degeneration

As people age, their immune systems age, too. And new research at Washington University School of Medicine in St. Louis suggests that aging immune cells increase the risk for age-related macular degeneration, a major cause of blindness in the United States.

5 Apr 2018

Researchers discover potential new therapeutic target for Ewing sarcoma

The sarcoma research group of the Bellvitge Biomedical Research Institute, led by Dr. Òscar Martínez-Tirado, has identified a potential new therapeutic target for Ewing sarcoma, the second most frequent bone cancer in children and adolescents, and a tumor known by its aggressiveness and tendency to metastasize.

5 Apr 2018

Researchers study how often healthcare providers prescribe anticholinergics for older adults

Anticholinergics are a class of medications that are often prescribed for allergies, lung disease, and urinary incontinence. They also often can increase health risks for older adults.

5 Apr 2018

Researchers create adult-like cardiac model by introducing early stimulation

Researchers are now able to use induced pluripotent stem cells to form a model of human adult-like cardiac muscle by introducing electric and mechanical stimulation at an early stage. Since this muscle is similar to the adult heart, it could serve as a better model for testing the effects of drugs and toxic substances than current tissue engineered heart models.

5 Apr 2018

Drugs News and Research

Former California state contractor sued over breach of HIV patient privacy

ALS and frontotemporal dementia share genetic connections

Study reveals how apoE4 gene confers risk for Alzheimer's disease in brain cells

Controlling blood pressure can prevent dementia in older African-Americans with hypertension

Using biomimicry for faster detection of disease outbreaks

Antiepileptic drug use linked to increased risk of Alzheimer's and dementia

Oxidative stress due to lack of tumor suppressor gene promotes cancer progression, study shows

Vascular stabilization biomarker helps optimize timing of anticancer therapies

Nosopharm and UIC reveal pharmacology of new class of antibiotics to combat drug resistance

U.S. population largely unaware of cancer drug shortages, study finds

Scientists develop indices that provide information about prognosis of cancers

Johns Hopkins scientist calls for more integration of epigenetics and genetics research

Scientists identify key genetic events responsible for initiating childhood leukemia

Waking up “sleeping” stem cells in the brain could improve its ability to repair injury

Scientists create organoids that could help guide bladder cancer treatment

Novel technology gives rise to mouse pancreatic tumors that resemble human cancer

Aging immune cells increase risk for macular degeneration

Researchers discover potential new therapeutic target for Ewing sarcoma

Researchers study how often healthcare providers prescribe anticholinergics for older adults

Researchers create adult-like cardiac model by introducing early stimulation

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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